Results 41 to 50 of about 2,032,630 (292)
New statistical high power test, obtained by differentiating random data of a small sample
Известия высших учебных заведений. Поволжский регион:Технические науки, 2021 Background. The research considers the problem of statistical analysis of small samples by synthesizing new statistical criteria. Materials and methods.
A.I. Ivanov +2 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Artificial Immune Systems: A Novel Approach to Pattern Recognition [PDF]
, 2002 This chapter introduces a new computational intelligence paradigm to perform pattern recognition, named Artificial Immune Systems (AIS). AIS take inspiration from the immune system in order to build novel computational tools to solve problems in a vast ...
Timmis, Jon, de Castro, Leandro N.
core
Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]
, 2012 A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Vivien Szabo +24 more
core +2 more sources
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
National Security Commission on Artificial Intelligence: Interim Report, November 2019 [PDF]
, 2019 Report presenting the National Security Commission on Artificial Intelligence's initial (NSCAI)'s preliminary assessment of artificial intelligence (AI).
National Security Commission on Artificial Intelligence (U.S.)
core
Continual Learning with Deep Artificial Neurons
CoRR, 2020 Neurons in real brains are enormously complex computational units. Among other things, they're responsible for transforming inbound electro-chemical vectors into outbound action potentials, updating the strengths of intermediate synapses, regulating their own internal states, and modulating the behavior of other nearby neurons.
Blake Camp +2 more
openaire +2 more sources
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
National Security Commission on Artificial Intelligence: Initial Report [PDF]
, 2019 A brief report summarizing the National Security Commission on Artificial Intelligence's activities, meetings, relationships with the U.S.
National Security Commission on Artificial Intelligence (U.S.)
core