Results 71 to 80 of about 17,633 (227)

The effect of cult-active medium on pregnancy outcomes after intracytoplasmic sperm injection in azoospermic men: A case-control study

International Journal of Reproductive BioMedicine, 2021
Background: Failed oocyte activation following intracytoplasmic sperm injection (ICSI) as a result of calcium deficiency is a major challenge. Objective: We compared the effect of cult-active medium (CAM) on ICSI outcomes in obstructive azoospermia cases.
Elham Asa, Rahil Janatifar, Seyedeh Saeideh Sahraei, Atefeh Verdi, Naser Kalhor   +4 more
doaj   +1 more source

Cell cycle regulation of a Xenopus Wee1-like kinase [PDF]

, 1995
Using a polymerase chain reaction-based strategy, we have isolated a gene encoding a Wee1-like kinase from Xenopus eggs. The recombinant Xenopus Wee1 protein efficiently phosphorylates Cdc2 exclusively on Tyr- 15 in a cyclin-dependent manner.
Coleman, Thomas R., Dunphy, William G., Mueller, Paul R.   +2 more
core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Effects of the conditioned medium of mesenchymal stem cells on mouse oocyte activation and development

Brazilian Journal of Medical and Biological Research, 2009
Mesenchymal stem cells (MSCs) have been reported to secrete a variety of cytokines and growth factors acting as trophic suppliers, but little is known regarding the effects of conditioned medium (CM) of MSCs isolated from femurs and tibias of mouse on ...
D.Q. Feng, Y. Zhou, B. Ling, T. Gao, Y.Y. Shi, H.M. Wei, Z.G. Tian   +6 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Ultrastructural and morphometric characterization of buffalo (Bubalus bubalis) ovarian preantral follicles [PDF]

, 2007
The main objective of the present study was to characterize buffalo preantral ovarian follicles. Parts of ovarian cortex, collected from postpubertal buffalo females that were having estrous cycles at regular intervals, were selected under ...
Báo, Sônia Nair, Luque, Maria Carolina Aquino, Mondadori, Rafael Gianella, Santin, Tiago Rollemberg   +3 more
core   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Epigenetic reprogramming during the maternal‐to‐zygotic transition

MedComm, 2023
After fertilization, sperm and oocyte fused and gave rise to a zygote which is the beginning of a new life. Then the embryonic development is monitored and regulated precisely from the transition of oocyte to the embryo at the early stage of ...
Yurong Chen, Luyao Wang, Fucheng Guo, Xiangpeng Dai, Xiaoling Zhang   +4 more
doaj   +1 more source

A Comparison of chromatin structure and PLCζ in sperms of subfertile oligoasthenoteratozoospermic and fertile men [PDF]

, 2016
زمینه و هدف: مهم ترین علل عدم فعال شدن تخمک پس از تکنیک های کمک باروری، عدم رهایش فاکتورهای اسپرمی فعال کننده تخمک و آسیب به DNA اسپرم است. PLCζ یکی از فاکتورهای اسپرمی است که در فعال شدن تخمک نقش دارد.
Ghaedi, Kamran., Nasr-Esfahani, Mohammad Hossein., Parivar, Kazem., Shahverdi, Abdolhossein., Tavalaee, Marzieh.   +4 more
core  

Swimming suppresses hepatic vitellogenesis in European female silver eels as shown by expression of the estrogen receptor 1, vitellogenin1 and vitellogenin2 in the liver [PDF]

, 2010
Background When European silver eels (Anguilla anguilla) venture into the Atlantic Ocean for their 6,000 km semelparous spawning run to the Sargasso Sea, they are still in a prepubertal stage.
Arjan P Palstra, Denhi Schnabel, Maaike C Nieveen, Herman P Spaink, Guido van den Thillart, S Dufour, B Vidal, BH Pedersen, BH Pedersen, AP Palstra, S Adachi, AP Palstra, V van Ginneken, A Palstra, PM Lokman, T Endo, M Olivereau, Y Nagahama, PJ Babin, T Todo, MC Lucas, G van den Thillart, NW Pankhurst, CMF Durif, NW Pankhurst, C Durif, T Verslycke, BJ Versonnen, A Palstra, H Kagawa, H Svedäng, AP Palstra, M Montero, C Teitsma, C Lethimonier, I Petersen, P Peyon, PM Lokman, HC Kwon, P Peyon, H Kamei, H Kamei, L Pérez, M Sbaihi, M Salem, M Salem, FW Tesch, DJ Jellyman, K Tsukamoto, K Aarestrup, M-E Sébert, M-E Sébert   +51 more
core   +3 more sources