Results 41 to 50 of about 371,444 (300)

Regenerative and hepatospecific activity of total RNA from xenogenic bone marrow cells

Вестник трансплантологии и искусственных органов, 2021
Objective: to study the peculiarities of the induction effect of total RNA (tRNA) from xenogenic bone marrow cells (BMCs) on regeneration processes in the recipient's native liver with extensive liver resection using an adoptive transfer model. Materials
N. A. Onishchenko, A. O. Nikolskaya, Z. Z. Gonikova, L. A. Kirsanova, M. Yu. Shagidulin, V. I. Sevastianov   +5 more
doaj   +1 more source

Geometric bionics: Lotus effect helps polystyrene nanotube films get good blood compatibility [PDF]

, 2009
Various biomaterials have been widely used for manufacturing biomedical applications including artificial organs, medical devices and disposable clinical apparatus, such as vascular prostheses, blood pumps, artificial kidney, artificial hearts, dialyzers
Chun Mao, Cun-Xia Liang, Hong-Ke Liu, Jian Shen, Jian-Chun Bao, Wen-Bo Zhao, Wen-Ping Luo, Xiao-Hua Huang, Xiao-Mei Hou, Ying-Hong Xiao   +9 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Decellularization of donor pancreatic fragment to obtain a tissue-specific matrix scaffold

Вестник трансплантологии и искусственных органов, 2020
One of the pressing issues in tissue engineering is on how to obtain an artificial matrix that can simulate a biological microenvironment for cells.
A. S. Ponomareva, L. A. Kirsanova, N. V. Baranova, V. A. Surguchenko, G. N. Bubentsova, Yu. B. Basok, I. A. Miloserdov, V. I. Sevastianov   +7 more
doaj   +1 more source

The role of apoptotic bone marrow cells in activation of liver regeneration

Вестник трансплантологии и искусственных органов, 2022
Objective: using an adoptive transfer model to study the cellular mechanisms involved in the formation of the initial stage of liver regeneration during intraperitoneal injection of a healthy recipient with apoptotic bone marrowderived mononuclear cells (
N. A. Onishchenko, A. O. Nikolskaya, Z. Z. Gonikova, L. A. Kirsanova, M. Yu. Shagidulin, V. I. Sevastianov   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Strategy for prophylactic application of peripheral va-ecmo in transplantation involving expected extremely prolonged ischemia time

Вестник трансплантологии и искусственных органов
Heart transplantation (HT) with extremely prolonged (>6 hours) graft ischemia is associated with severe cardiac graft dysfunction. The high efficiency of prophylactic (preoperative initiation) veno-arterial extracorporeal membrane oxygenation (VA-ECMO)
V. N. Poptsov, V. M. Zakharevich, E. A. Spirina, A. I. Skokova, A. K. Solodovnikova, A. S. Ignatkina, A. A. Kuznetsova, G. B. Glinkin   +7 more
doaj   +1 more source

DISTURBANCE OF THE CARDIOMYOCYTE’S MACROMOLECULAR STRUCTURE IN HEART ALLOGRAFTS AS A SIGN OF CHRONIC REJECTION

Вестник трансплантологии и искусственных органов, 2012
Chronic rejection, especially cardiac allograft vasculopathy, is a major limiting factor for long-term transplant survival. This process affects not only the blood vessels, but also cardiomyocytes.
A. G. Kupriyanova, L. V. Beletskaya, I. M. Ilyinsky, V. A. Zaidenov, N. P. Mozeiko, R. S. Saitgareev, A. Y. Kormer, A. M. Golts, V. M. Zakharevich, S. V. Gautier   +9 more
doaj   +1 more source

MicroRNA expression levels in lung recipients: correlations with clinical and laboratory data

Вестник трансплантологии и искусственных органов, 2020
Objective: to evaluate the expression levels of miRNA (miR-27, miR-101, miR-142, miR-339 and miR-424) and its relationship with clinical and laboratory parameters in lung transplant recipients. Materials and methods. The study included 57 lung recipients
O. P. Shevchenko, S. O. Sharapchenko, O. M. Tsirulnikova, I. V. Pashkov, O. E. Gichkun, D. A. Velikiy, E. F. Shigaev, D. O. Oleshkevich, M. T. Bekov   +8 more
doaj   +1 more source

Heart transplant in a patient with persistent left superior vena cava

Вестник трансплантологии и искусственных органов, 2021
Objective: to present our own experience of heart transplantation in a patient with persistent left superior vena cava (PLSVC). A clinical case of successful orthotopic heart transplantation using the biatrial technique in a patient with PLSVC drainage ...
G. V. Aniskevich, G. A. Sadrieva, V. N. Poptsov, E. A. Spirina, V. I. Orlov, R. Sh. Saitgareev   +5 more
doaj   +1 more source