Results 131 to 140 of about 2,003,440 (290)

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

Transport mechanical ventilation for adults in the prehospital setting: a practical approach

Colombian Journal of Anesthesiology
Mechanical ventilation (MV) is a convenient therapeutic intervention modality in prehospital settings for managing urgent situations requiring ventilatory support due to respiratory failure, regardless of the etiology.
Jorge Iván Gil Mayorga, Valentina Carrillo Jojoa, Jorge Reinerio Escobar Morantes   +2 more
doaj   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

Advanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li   +7 more
wiley   +1 more source

Self-extubation in critically ill patients: new predictors identified in a multicenter retrospective study

Colombian Journal of Anesthesiology
Introduction: Although COVID-19 is now considered an endemic disease, understanding the factors associated with planned extubation and self-extubation in this population remains essential. Objective: To identify factors associated with self-extubation,
Carlos Eduardo Laverde-Sabogal, Carmelo José Espinosa-Almanza, Juan Pablo Álzate, Carlos Rosero, Margarita Arias, Julián Salazar Morales, Antonia Ramírez, Juan Camilo Aguado-Valderrama, Manuel E. Torres, Santiago Suárez Gómez, Daniela Patiño   +10 more
doaj   +1 more source

SCTR–Expressing Astrocyte–Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac–Foxc2 Epigenetic Axis in an AMPK‐Dependent Manner

Advanced Science, EarlyView.
Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng, Jing Liu, Juanjuan Dai, Min Wu, Wentao Wang, Mengdi Zhang, Shujun Jiang, Yifan Cao, Lihong Xu, Lin Du, Dan Wang, Di Zhao, Gaofeng Qin, Dong Wang, Wei Li, Chen Li   +15 more
wiley   +1 more source

The ratio of inspiration and expiration phases at the start of artificial ventilation of the lungs in newborns with hypoxemic respiratory failure

Сибирский научный медицинский журнал
The recommended inhalation time for artificially respirated newborns is 0,25 to 0,35 second. With a respiratory rate of 40-60 min-1, the inhalation to exhalation time (Ti:Te) ratio is average 1:3.
A. N. Shmakov, К. V. Budarova, V. N. Kokhno, N. L. Elizar’eva   +3 more
doaj   +1 more source

Thymectomy during Myasthenic Crisis under Artificial Respiration. [PDF]

Ann Thorac Cardiovasc Surg, 2019
Onuki T, Ueda S, Otsu S, Yanagihara T, Kawakami N, Yamaoka M, Inagaki M.   +6 more
europepmc   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

Wearable E‐Textiles for Cardiovascular Monitoring: Materials, Devices, and Integrated Systems

Advanced Science, EarlyView.
The graphical abstract highlights the role of conductive materials and textile fabrication techniques in enabling smart textiles for cardiovascular applications. It showcases textile‐based ECG monitoring, pulse sensing, hemodynamic monitoring, and cardiovascular tissue engineering, while emphasizing the challenges and design considerations that govern ...
Bangul Khan, Mahmoud Tavakoli, Norbert Radacsi, Bee Luan KHOO   +3 more
wiley   +1 more source

Modelling Characteristic of Respiration on Artificial Ripening System of Climacteric Fruit Based on Logistic Equation

, 2011
As perishable products, fruit have limited shelf life that could disturb the supply continuity on the market. A system consists of Cold storage and artificial ripening chamber could be a solution to this problem.
., Sutrisno, Vanani, Kem Trimaya
core   +1 more source