Results 191 to 200 of about 1,890,030 (376)

A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme

Advanced Science, EarlyView.
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun, Chao Dou, Weizhu Yan, Pengpeng Chen, Lu Zhang, Dan Zhou, Yanhui Zheng, Zhaolin Long, Shoujie Li, Xiaoqing Xu, Qiuxia Huang, Xiaofeng Zhu, Wei Cheng   +12 more
wiley   +1 more source

Palliative extubation in pediatrics: a scoping review. [PDF]

J Pediatr (Rio J)
Affonseca CA, de Carvalho LFA, Anchieta LM.   +2 more
europepmc   +1 more source

SIMPLE DEVICES FOR EFFECTIVE ARTIFICIAL RESPIRATION IN EMERGENCIES

, 1913
S. Meltzer
semanticscholar   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

An integrated framework for reducing construction carbon emissions using real-time monitoring and econometrics. [PDF]

Sci Rep
Bai F, Cai Q, Zheng X, Lei Z, Wang W, Liang J, Guo J, Qi J.   +7 more
europepmc   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Optimization of Chemical Defined Medium for <i>Lactobacillus brevis</i> Based on Artificial Intelligence. [PDF]

Eng Life Sci
Yu C, Yang X, Ren X, Xia J.
europepmc   +1 more source

Deadspace Requirement for Normal Alveolar Ventilation During Artificial Respiration in Man [PDF]

, 1967
Kunio Suwa, BENNIE GEFFIX, HENXIXC POXTOFFIDAX   +2 more
openalex   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Altered surface behaviour in earthworms (Lumbricus terrestris) under artificial light at night. [PDF]

Oecologia
Cai J, Bennie J, Gaston KJ.
europepmc   +1 more source