Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby +6 more
wiley +1 more source
Performance of artificial intelligence models for monitoring psychological stress using noncontact physiological signals: a systematic review and meta-analysis. [PDF]
Han X, Wang Q, Gao L, Cao H.
europepmc +1 more source
Objective The ALS Functional Rating Scale–Revised decline rate compresses trajectory shape into a single number, potentially missing distinct phenotypes. We tested whether shape identifies phenotypes that rate does not distinguish, and whether post‐hoc analysis recovers a hidden ultrarapid subgroup. Methods From the Piemonte and Valle d'Aosta register (
Andrea Calvo +20 more
wiley +1 more source
Enteric Methane Emission and Milk Component Profiles of Holstein and Jersey Cows: A Respiration Chamber Study. [PDF]
Park J +7 more
europepmc +1 more source
The Mind From Within: Visceral Roots of Human Cognition. [PDF]
Monti A, Aglioti SM.
europepmc +1 more source
Letter to the Editor: Artificial intelligence in nephrology point-of-care ultrasonography - opportunities, limitations, and future directions. [PDF]
Koratala A, Ferreira F, Diniz H.
europepmc +1 more source
CT-less attenuation correction in a patient with BMI of 77. [PDF]
Bartel T +5 more
europepmc +1 more source
Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source
Life Cells for future energy systems: adaptation, evolution and exploration. [PDF]
Lai J, Zhang F, Li L, Wu F, Chen R.
europepmc +1 more source
Cardio-respiratory deep learning model to predict hospital admission from emergency department electrocardiogram images and respiration videos: a prospective study. [PDF]
Chen GY +7 more
europepmc +1 more source

