Results 51 to 60 of about 66,981 (213)

Multimodal Measurement and Stimulation System to Investigate the Effects of Noninvasive Electrical Stimulation of the Phrenic Nerve

Current Directions in Biomedical Engineering
Mechanical ventilation, as performed daily in intensive care units, can lead to ventilator-induced diaphragmatic dysfunction. A reduction in diaphragmatic force generation can occur within the first 24 h.
Kalla Tim, Wegert Laureen, Lange Irene, Haueisen Jens, Hunold Alexander   +4 more
doaj   +1 more source

Pneumonia associada à ventilação mecânica: análise de fatores epidemiológicos na confecção de estratégias de profilaxia e terapêutica Ventilator associated pneumonia: confection of a strategy of prophylaxis and management based on the analysis of epidemiology

Revista Brasileira de Terapia Intensiva, 2006
JUSTIFICATIVA E OBJETIVOS: Tem-se creditado à pneumonia associada à ventilação mecânica (PAVM) impacto variável, em termos de mortalidade, aumento da permanência hospitalar e tempo de ventilação mecânica. O objetivo deste estudo foi definir três aspectos:
Edgard do Carmo Neto, Paulo César de Souza, Frederico Azevedo, Marcelo Elisio Lugarinho   +3 more
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Ventilación no invasiva con presión positiva

Revista Cubana de Medicina, 2002
Se hizo una revisión bibliográfica sobre el uso actual de la ventilación no invasiva con presión positiva y se aludió al mejor confort y ventajas que ofrece con respecto a la invasiva convencional.
Alfredo Triolet Gálvez, María Isabel Bofill Oliva, Ana Rosa Estrada Alonso, Ana Amelia Pino Álvarez   +3 more
doaj  

Influence of neck tissue conductivities on the phrenic nerve activation threshold during non-invasive electrical stimulation

Current Directions in Biomedical Engineering
Phrenic nerve stimulation is used as an artificial ventilation method to reduce the adverse effects of mechanical ventilation, such as ventilator-induced diaphragmatic dysfunction. Detailed computational models and electromagnetic simulations are used to
Wegert Laureen, Di Rienzo Luca, Codecasa Lorenzo, Ziolkowski Marek, Hunold Alexander, Kalla Tim, Lange Irene, Haueisen Jens   +7 more
doaj   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Critical Care Management Following Lung Transplantation

Journal of Chest Surgery, 2022
Postoperative critical care management for lung transplant recipients in the intensive care unit (ICU) has expanded in recent years due to its complexity and impact on clinical outcomes. The practical aspects of post-transplant critical care management,
Kyeongman Jeon
doaj   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source