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Classification of Artificial Tears

1998
Natural tears serve three main functions: they maintain the metabolism of the ocular surface tissues, afford a smooth surface that allows regular light refraction, and lubricate the ocular surface to facilitate blinking. They also have other functions, such as specific and non-specific antimicrobial and buffer effects, etc. Natural tears have a complex
J. Murube, A. Paterson, E. Murube
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Whatʼs Artificial in Artificial Tears?

Optometry and Vision Science, 1986
After reviewing tear film physiology, and tear film disorders, the author discusses the ingredients found in artificial tear solutions. Choosing the best artificial tear solution for each patient is often confusing because many solutions are available.
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Artificial Tear Issues

1994
The designing of artificial tear products has been undergoing constant reevaluation for many decades. Currently available artificial tear formulations differ remarkably with regard to their compositions. Today, significant controversies exist among pharmaceutical scientists in this field.
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Toxic preservatives in artificial tears

Ugeskrift for Læger
Dry eye disease (DED) is a common condition, especially among the elderly. Artificial tears are formulated to relieve the symptoms of DED. However, selecting the most suitable option can be challenging, as the products differ in various aspects, including eligibility for reimbursement, pricing, packaging formats, composition, and presence of ...
Christian Eggers Østergaard, Rasmussen   +6 more
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Effect of Artificial Tear Solutions and Saline on Tear Film Evaporation

Optometry and Vision Science, 1990
ABSTRACT The effect on tear evaporation of two artificial tear solutions is compared with that of an equal volume of saline instilled into the eye. Changes in tear evaporation rates (TER) were measured with a modified Servomed Evaporimeter in a cross‐over study of nine subjects.
G R, Trees, A, Tomlinson
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Effect of preservatives in artificial tear solutions on tear film evaporation *

Ophthalmic and Physiological Optics, 1991
It has been suggested that certain preservatives in artificial tears may affect the stability of the tear film lipid layer. In the present study, tear film evaporation rate (TER) was measured with a modified Servomed Evoporimeter to determine whether preservatives affected tear stability. Two solution combinations were compared in a cross‐over study of
A, Tomlinson, G R, Trees
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Stability of Cyclosporine 1% in Artificial Tears

Journal of Ocular Pharmacology and Therapeutics, 1996
We wished to determine the stability of frozen, refrigerated, and room temperature topical cyclosporine 1% in artificial tears (Tears Plus). Cyclosporine 1% eye drops were made in artificial tears prior to the manufacturers recommendations of using a lipid soluble vehicle, such as olive oil.
R G, Fiscella, H, Le, T T, Lam, S, Labib
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Effect of Artificial Tears on Visual Acuity

American Journal of Ophthalmology, 2005
To study the effect of commonly used preservative free artificial tear, carboxymethylcellulose (CMC) 0.5% (Refresh Plus, Allergan, Irvine, California) on visual acuity in symptomatic dry eye (SDE) and asymptomatic dry eye (ADE) patients.Nonrandomized prospective clinical trial.Prospective study involving 20 patients (40 eyes) with SDE and 20 patients ...
Mohammad-Reza, Nilforoushan   +2 more
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Colloid Osmotic Pressure of Artificial Tears

Journal of Ocular Pharmacology and Therapeutics, 1985
While the total osmolality of the aqueous tears and tear substitutes has received much attention in the past few years, the colloidal osmolality or the oncotic pressure (which includes the Donnan effect), has received practically no attention except for one single foreign publication.
F J, Holly, E D, Esquivel
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A Unique Therapeutic Artificial Tear Formulation

1994
The tear film has a unique electrolyte balance distinct from aqueous humor and serum.1. We postulated that this electrolyte balance was critical for the maintenance of ocular surface health.
J P, Gilbard, S R, Rossi
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