Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission? [PDF]
Microorganisms, 2021 In 2020, a global pandemic was declared following the spread of SARS-CoV-2, the pathogen responsible for COVID-19. The risk of infection is high due to the ease of transmission, which can occur orally, through droplets, or via contact with contaminated ...
Francesco Petrillo +10 more
doaj +5 more sources
Broad-Spectrum Antimicrobial Activity of Oftasecur and Visuprime Ophthalmic Solutions [PDF]
Microorganisms, 2023 Due to the wide etiology of conjunctivitis, the expensive and time-consuming diagnosis requires new therapeutic strategies with broad-spectrum antimicrobial activity and nonselective mechanisms of action.
Federica Dell’Annunziata +8 more
doaj +4 more sources
Ophthalmic Solutions with a Broad Antiviral Action: Evaluation of Their Potential against Ocular Herpetic Infections [PDF]
Microorganisms, 2022 HSV-1 can be associated with severe and recurrent eye infections characterized by a strong inflammatory response that leads to blepharoconjunctivitis, epithelial and stromal keratitis, and retinal necrosis. The incidence of HSV-1 keratitis is 1.5 million
Carla Zannella +9 more
doaj +6 more sources
Changes of tear film lipid layer thickness by 3% diquafosol ophthalmic solutions in patients with dry eye syndrome [PDF]
International Journal of Ophthalmology, 2019 AIM: To evaluate the quantitatively changes in lipid layer thickness (LLT) when 3% diquafosol eye drop is used for dry eye patients using the tear film interferometer.
Dong-Hyun Kang +7 more
doaj +3 more sources
BMC Ophthalmology, 2009 Background Benzalkonium chloride (BAC) is a common preservative used in ophthalmic solutions. The aim of this study was to compare the cytotoxic effects of BAC-containing ophthalmic solutions with a BAC-free ophthalmic solution using an organotypic 3 ...
Jessen Bart A, Khoh-Reiter Su
doaj +3 more sources
Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation. [PDF]
Pharm Res, 2023 Background The development of generic ophthalmic drug products is challenging due to the complexity of the ocular system, and a lack of sensitive testing to evaluate the interplay of physiology with ophthalmic formulations.
Le Merdy M +6 more
europepmc +2 more sources
Allergic Conjunctivitis Management: Update on Ophthalmic Solutions. [PDF]
Curr Allergy Asthma RepThe aim of this review, is to present an updated revision of topical management of SAC and PAC, based on the available scientific evidence and focused on the impact of ophthalmic solution formulations on eye surface.
Leonardi A +10 more
europepmc +2 more sources
Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease. [PDF]
Clin Ophthalmol, 2019 Dry eye disease (DED) is a multifactorial disease of ocular surface and tear film, and is a common disorder treated by eye care providers. It is well established that ocular surface inflammation has an important role in the pathophysiology of DED and ...
de Oliveira RC, Wilson SE.
europepmc +2 more sources
Microbial Contamination and Antimicrobial Resistance in Use of Ophthalmic Solutions at the Department of Ophthalmology, Jimma University Specialized Hospital, Southwest Ethiopia. [PDF]
Can J Infect Dis Med Microbiol, 2019 Background Eye drops are most frequently used medications in ophthalmology. The carriage of pathogenic organisms to eyes through the agency of eye drops has presented a serious problem for several decades. The objective of this study was to determine the
Tamrat L, Gelaw Y, Beyene G, Gize A.
europepmc +2 more sources
Stability of Ophthalmic Atropine Solutions for Child Myopia Control
Pharmaceutics, 2020 Myopia is an ophthalmic condition affecting more than 1/5th of the world population, especially children. Low-dose atropine eyedrops have been shown to limit myopia evolution during treatment.
Baptiste Berton +6 more
doaj +2 more sources