Results 41 to 50 of about 7,961,527 (324)

Rapid Campimetry in glaucoma – correspondence with standard perimetry and OCT

Scientific Reports
The Rapid Campimetry (RC), a kinetic visual field test proved to reliably detect visual field defects within the central 10° degrees, the most crucial part for visual acuity and quality of life, affected even at very early stages of glaucoma, within a ...
Nidele Djouoma, Fabian Müller, Francie H. Stolle, Friedrich Hoffmann, Hagen Thieme, Michael B. Hoffmann, Khaldoon O. Al-Nosairy   +6 more
doaj   +1 more source

Safety and efficacy of MIM-D3 ophthalmic solutions in a randomized, placebo-controlled Phase 2 clinical trial in patients with dry eye

Clinical Ophthalmology, 2013
Purpose To evaluate the safety and efficacy of ophthalmic MIM-D3, a tyrosine kinase TrkA receptor agonist, in patients with dry eye. Design A prospective, two-center, randomized, double-masked, placebo-controlled Phase 2 study. Methods A total of 150 dry
K. Meerovitch, G. Torkildsen, John D Lonsdale, Heidi Goldfarb, T. Lama, G. Cumberlidge, G. Ousler   +6 more
semanticscholar   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

THE STERILISATION OF SOLUTIONS FOR OPHTHALMIC USE [PDF]

The Lancet, 1893
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openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Evaluation of induced and spontaneous contamination of ocular medications after first opening

Microbiologia Medica, 2008
In order to evaluate whether ophthalmic preparations can be safely used within 12 hours after first opening, four different sterile ocular medications,were opened and tested for spontaneous bacterial contamination after exposure to air.
Anna Marchese, Simone Cagnacci, Eugenio A. Debbia   +2 more
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

The Antibacterial Effect of a Preservative-free Multi-dose Eye Dropper Using Air Pressure Differentials

Korean Journal of Clinical Laboratory Science
This study aimed to evaluate the antibacterial effects of a newly designed preservative-free multi-dose eye dropper that addresses various shortcomings found in conventional models.
Da-Been LEE, Seung-Lim YOO, Minchul SONG, Mihee NA, Dae-Wui YOON   +4 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

A randomised, double-masked comparison study of diquafosol versus sodium hyaluronate ophthalmic solutions in dry eye patients

British Journal of Ophthalmology, 2012
Aims To compare the efficacy and safety of 3% diquafosol ophthalmic solution with those of 0.1% sodium hyaluronate ophthalmic solution in dry eye patients, using mean changes in fluorescein and rose bengal staining scores as endpoints.
E. Takamura, K. Tsubota, Hitoshi Watanabe, Y. Ohashi   +3 more
semanticscholar   +1 more source