Results 51 to 60 of about 7,961,527 (324)

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

Advanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang, Ilya Pyatnitskiy, Yanshu Shi, Kai Wing Kevin Tang, Yi Xie, Sihan Yu, Thomas Wynn, Xiangping Liu, Ju‐Chun Hsieh, Jinmo Jeong, Weilong He, Brinkley Artman, Anakaren Romero Lozano, Xi Shi, Arjun Sangani, Lief E Fenno, Samantha Santacruz, Banglin Chen, Huiliang Wang   +18 more
wiley   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Age and Sex Variation in the Duration of Action and Corneal Touch Threshold (CTT) following Instillation of 0.5% Topical Ophthalmic Proparacaine and Tetracaine Hydrochlorides

Journal of Ophthalmology, 2021
Purpose. We investigated the effect of age and sex on corneal touch threshold (CTT) and duration of action following administration of 0.5% topical ophthalmic proparacaine and tetracaine hydrochlorides. Methods. A prospective, randomized, subject-masked,
Samuel Kyei, Nana Yaw Abaka Dadzie, Ebenezer Zaabaar, Kwasi Antwi Asamoah Dwomoh, Kofi Asiedu   +4 more
doaj   +1 more source

Comparative analysis of safety and efficacy of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2% and Bepotastine besilate 1.5% in allergic conjunctivitis

Indian Journal of Ophthalmology, 2021
Purpose: To compare the efficacy and safety of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2%, and Bepotastine besilate 1.5% ophthalmic solutions in the treatment of allergic conjunctivitis. Methods: This is a prospective, observer-masked, comparative
Shruti Ayyappanavar, Sriya Sridhar, Kiran Kumar, C R Jayanthi, Suresh Babu Gangasagara, B L Sujatha Rathod, B Preethi, Preeti Mittal   +7 more
doaj   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source

Effectiveness of autologous serum eye drops in the treatment of corneoconjunctival burns

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Background: ocular burns are a health problem since they have a relevant place in the ophthalmological practice.Objective: to assess the effectiveness of 50 % autologous serum eye drops combined with the conventional treatment of corneoconjunctival burns
Yanier Serrano-García, Alena de los Ángeles Vejerano-Duany, María Del Carmen González-Fernández, Leonor Gallardo-Roca, Taimi Miranda-Vergara   +4 more
doaj  

A Note on the Stability of Ophthalmic Solutions Containing Pilocarpine Hydrochloride Alone and with Eserine

, 1963
The stability of pilocarpine hydrochloride in ophthalmic solutions after heating and storage, and the influence of light and of two types of containers on stability, have been investigated. Pilocarpine was assayed by a modification of a published method.
Rune Fagerström
core   +1 more source

Nocturnal Intraocular Pressure Monitoring With a Soft Contact Lens Sensor for Glaucoma Management

Advanced Materials, EarlyView.
A soft contact lens sensor enables continuous, noninvasive monitoring of nocturnal intraocular pressure (IOP) under closed‐eye sleep conditions. By integrating a highly compliant inductive–capacitive circuit onto a commercial lens, the device achieves record sensitivity and stable performance.
Yumin Dai, Tristan Michael Long, Oluwabunmi T. Oladele, Youngoh Lee, Feiyang Li, Ziheng Wang, Yeonji Oh, Junsang Lee, Taewoong Park, Tianhao Yu, Seokkyoon Hong, Kyeonghee Lim, Jinheon Jeong, Dawn Meyer Schneider, Hyerim Ra, Bryan W. Boudouris, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Chi Hwan Lee   +19 more
wiley   +1 more source

Vision-Based Eye Image Classification for Ophthalmic Measurement Systems

Sensors, 2022
The accuracy and the overall performances of ophthalmic instrumentation, where specific analysis of eye images is involved, can be negatively influenced by invalid or incorrect frames acquired during everyday measurements of unaware or non-collaborative ...
Giovanni Gibertoni, Guido Borghi, Luigi Rovati   +2 more
doaj   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source