Results 41 to 50 of about 141,099 (208)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Comments on "'Lake Woebegone,' Twenty Years Later"
Nonpartisan Education Review, 2006 J. J. Cannell’s article on the so-called “Lake Woebegone” effect for K-12 educational testing systems is mostly an historical account of technical issues and policy considerations that led in part to development of new types of test instruments for K-12 ...
D. J. McRae, Ph.D.
doaj
Insights into ImagingObjective Radiologists often face challenges in differentiating benign from malignant sacral bone lesions due to their similar imaging characteristics. This study aimed to develop an ensemble deep learning (DL) model that can preoperatively distinguish ...
Ping Yin +8 more
doaj +1 more source
Mapping Mutual Fund Investor Characteristics and Modeling Switching Behavior [PDF]
, 2003 Securing a mutual fund that meets investment goals is an important reason why some investors exclusively stay with a particular mutual fund and others switch funds within their fund family.
Akhter, Syed H. +2 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Reinforcement Learning for Bandit Neural Machine Translation with Simulated Human Feedback
, 2017 Machine translation is a natural candidate problem for reinforcement learning from human feedback: users provide quick, dirty ratings on candidate translations to guide a system to improve.
Boyd-Graber, Jordan +2 more
core +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source
A Generalized Method for Integrating Rule-based Knowledge into Inductive Methods Through Virtual Sample Creation [PDF]
, 2011 Hybrid learning methods use theoretical knowledge of a domain and a set of classified examples to develop a method for classification. Methods that use domain knowledge have been shown to perform better than inductive learners.
Iqbal, Ridwan Al
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source