Results 61 to 70 of about 15,100 (228)

Psoriasis ostrácea con artritis psoriática tratada con infl iximab

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2019
La psoriasis es una enfermedad crónica de la piel, caracterizada por placas eritematodescamativas debidas a proliferación celular e inflamación. Una de las formas clínicas es la psoriasis ostrácea, formada por lesiones hiperqueratósicas de superficie ...
Christian Burbano, Adriana Motta, Mario Díaz, Mariam Rolón   +3 more
doaj  

Reachable Workspace as a Clinical Outcome for Upper Extremity Function: A Narrative Review

Muscle &Nerve, EarlyView.
ABSTRACT Motion sensing technology can be utilized to capture detailed upper extremity (UE) motion to reconstruct an individual's three‐dimensional (3D) reachable workspace (RWS). The RWS can be quantified as relative surface area (RSA), providing an innovative surrogate measure to assess UE mobility and function.
Jay J. Han, Lawrence J. Hayward, Christina Adams, Juan Perez‐Ibarra   +3 more
wiley   +1 more source

Skin Abnormalities at Checkpoint Inhibitor Therapy Initiation Are Associated With Skin Rash Development in Oncology Patients

Allergy, EarlyView.
Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.
Taras Lyubchenko, Evgeny Berdyshev, Ryan M. Weight, Olivia Xiao, Neil J. Shah, Alina Markova, Mario E. Lacouture, Jeffrey A. Kern, Elena Goleva, Donald Y. M. Leung   +9 more
wiley   +1 more source

Estudio comparativo de la calidad de vida de los pacientes con artritis reumatoide usuarios de metotrexato vs usuarios de fármacos anti - tnf más metrotrexato en el servicio de reumatología del Hospital de Especialidades Eugenio Espejo en el periodo julio – agosto del 2017

, 2017
La artritis reumatoide es una enfermedad crónica, sistémica y discapacitante que produce daño articular irreversible, alterando la calidad de vida de quienes la padecen. Objetivo.
García Cadena, María Ángela
core   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Caracterización de pacientes con diagnóstico de Artritis Reumatoidea tratados con agentes biológicos y sus principales eventos adversos en el Servicio de Reumatología del Hospital Carlos Andrade Marín durante el periodo 2012 – 2018

, 2019
La artritis reumatoide (AR) es una enfermedad sistémica autoinmune, caracterizada por producir inflamación crónica articular, el objetivo de este estudio es conocer el perfil epidemiológico y características clínicas del paciente con artritis ...
Villalba Saltos, Betzy Helena
core   +1 more source

Mitochondrial permeability transition in skeletal muscle phenocopies muscle alterations seen in cancer cachexia and other wasting conditions

The Journal of Physiology, EarlyView.
Abstract figure legend Skeletal muscle wasting conditions are characterized by muscle fibre atrophy, mitochondrial respiratory dysfunction, mitochondrial depletion and fragmentation of acetylcholine receptor (AChR) cluster at the neuromuscular junction.
Maya Semel, Cole Lukasiewicz, Sarah Skinner, Mark R. Viggars, Sung Gi Noh, Martin Picard, Abbey‐Gale Mannings, Michael S. Cohen, Dennis W. Wolan, Terence E. Ryan, Russell T. Hepple   +10 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, Volume 78, Issue 10, Page 1424-1437, October 2026.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Agentes Biológicos en el tratamiento de la Artritis Reumatoide

Acta Médica Costarricense, 2011
El mayor conocimiento inmuno-patológico de la artritis reumatoide permitió mediante una sofisticada tecnología molecular elaborar antagonistas contra blancos específicos en diversos pasos de la inmuno patogenia de la enfermedad.
José Francisco Díaz-Coto, Pablo Monge-Zeledón, Francisco Brenes-Silesky, Christian Arias-Howlett   +3 more
doaj  

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

Arthritis Care &Research, Volume 78, Issue 10, Page 1544-1551, October 2026.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R. Rasooly, Pamela F. Weiss   +5 more
wiley   +1 more source