Results 61 to 70 of about 15,727 (226)

Psoriasis ostrácea con artritis psoriática tratada con infl iximab

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2019
La psoriasis es una enfermedad crónica de la piel, caracterizada por placas eritematodescamativas debidas a proliferación celular e inflamación. Una de las formas clínicas es la psoriasis ostrácea, formada por lesiones hiperqueratósicas de superficie ...
Christian Burbano, Adriana Motta, Mario Díaz, Mariam Rolón   +3 more
doaj  

Reachable Workspace as a Clinical Outcome for Upper Extremity Function: A Narrative Review

Muscle &Nerve, EarlyView.
ABSTRACT Motion sensing technology can be utilized to capture detailed upper extremity (UE) motion to reconstruct an individual's three‐dimensional (3D) reachable workspace (RWS). The RWS can be quantified as relative surface area (RSA), providing an innovative surrogate measure to assess UE mobility and function.
Jay J. Han, Lawrence J. Hayward, Christina Adams, Juan Perez‐Ibarra   +3 more
wiley   +1 more source

Skin Abnormalities at Checkpoint Inhibitor Therapy Initiation Are Associated With Skin Rash Development in Oncology Patients

Allergy, EarlyView.
Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.
Taras Lyubchenko, Evgeny Berdyshev, Ryan M. Weight, Olivia Xiao, Neil J. Shah, Alina Markova, Mario E. Lacouture, Jeffrey A. Kern, Elena Goleva, Donald Y. M. Leung   +9 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Mitochondrial permeability transition in skeletal muscle phenocopies muscle alterations seen in cancer cachexia and other wasting conditions

The Journal of Physiology, EarlyView.
Abstract figure legend Skeletal muscle wasting conditions are characterized by muscle fibre atrophy, mitochondrial respiratory dysfunction, mitochondrial depletion and fragmentation of acetylcholine receptor (AChR) cluster at the neuromuscular junction.
Maya Semel, Cole Lukasiewicz, Sarah Skinner, Mark R. Viggars, Sung Gi Noh, Martin Picard, Abbey‐Gale Mannings, Michael S. Cohen, Dennis W. Wolan, Terence E. Ryan, Russell T. Hepple   +10 more
wiley   +1 more source

Changes in Midrange and End Range Adjacent Segment Motion 3 Years After One‐ Or Two‐Level Cervical Arthrodesis

JOR SPINE, Volume 9, Issue 4, December 2026.
ABSTRACT Background Biomechanical cadaver studies consistently find that cervical arthrodesis leads to increased motion adjacent to the arthrodesis. However, in vivo evidence indicates adjacent segment end range motion does not reliably increase at 1 year after one‐level or two‐level cervical arthrodesis.
Clarissa M. LeVasseur, Samuel W. Pitcairn, Xinyi Dan, Yan Ma, David O. Okonkwo, Jeremy D. Shaw, William F. Donaldson, Joon Y. Lee, William J. Anderst   +8 more
wiley   +1 more source

Artritis Idiopática Juvenil

, 2009
La Artritis Idiopática Juvenil (AIJ), es un término que describe a un grupo heterogéneo de artritis inflamatoria crónica, que ocurre en personas menores de 16 años de edad, tiene una duración de 6 semanas o más, y donde otras patologías han sido ...
Morel Ayala, Zoilo
core  

Agentes Biológicos en el tratamiento de la Artritis Reumatoide

Acta Médica Costarricense, 2011
El mayor conocimiento inmuno-patológico de la artritis reumatoide permitió mediante una sofisticada tecnología molecular elaborar antagonistas contra blancos específicos en diversos pasos de la inmuno patogenia de la enfermedad.
José Francisco Díaz-Coto, Pablo Monge-Zeledón, Francisco Brenes-Silesky, Christian Arias-Howlett   +3 more
doaj  

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, Volume 78, Issue 11, Page 1618-1630, November 2026.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, Volume 78, Issue 11, Page 1781-1790, November 2026.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source