Results 11 to 20 of about 22,237 (159)

ANÁLISE IN SILICO EM AQUAPORINA-1 PLAQUETÁRIA MUTANTE E REPERCUSSÕES TROMBOGÊNICAS

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introdução/Objetivos: A aquaporina-1 (AQP1) é um canal regulador osmótico. Faz-se presente em diversas células, como hemácias e plaquetas. Nestas, aprimora a hemostasia intensificando o processo de baloneamento e o estímulo à microvesiculação e ao ...
ARV Prudêncio, W Baleotti-Júnior
doaj   +1 more source

The Characteristics of Opportunistic Infections Among AIDS Patiaents in BRSU Tabanan in 2019

open access: yesWMJ (Warmadewa Medical Journal), 2019
According to WHO and UNAIDS report, there has been dramatic increase of HIV/AIDS cases in Indonesia. The objective of the study was to determine the distribution of opportunistic infections in people with HIV / AIDS and the use of antiretroviral drugs in
Putu Prayoga Ratha   +1 more
doaj   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

open access: yesAngewandte Chemie, EarlyView.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang   +7 more
wiley   +2 more sources

Genetic characterization of a novel pheasant-origin orthoreovirus using Next-Generation Sequencing

open access: yesPLoS ONE, 2022
A field isolate (Reo/SDWF /Pheasant/17608/20) of avian orthoreovirus (ARV), isolated from a flock of game-pheasants in Weifang, Shandong Province, was genetically characterized being a field variant or novel strain in our recent research studies in ...
Yi Tang   +5 more
doaj   +2 more sources

Perception of People Living With HIV/AIDS Affecting Lost to Follow-Up of ARV Therapy

open access: yesCritical Medical and Surgical Nursing Journal, 2019
Introduction: HIV/AIDS sufferers must consume antiretrovirals every day and control routinely each month to take ARVs in the hospital. The condition make patients having a risk of lost to follow up attitude. The purpose of this study was to determine the
Lilik Manowati   +2 more
doaj   +1 more source

Relationship Between Multimorbidity, Nutritional Status and Duration of ARV Treatment to Major Signs of HIV at RSUD Dr. Soetomo Surabaya

open access: yesAgriHealth
People living with HIV/AIDS (PLWHA) can have better health outcomes with early identification of the AIDS phase. In the first three years, PLWHA may progress to the AIDS stage.
Kartika Alifia   +4 more
doaj   +1 more source

Synergistic pathogenicity of avian orthoreovirus and Staphylococcus aureus on SPF chickens

open access: yesPoultry Science, 2023
: Avian arthritis is a relatively common disease in the poultry industry, the cause of which is complex. Bacterial arthritis is often caused by infection of Staphylococcus aureus (S. aureus), whereas viral arthritis is caused by avian orthoreovirus (ARV).
Xiaoning Jiang   +8 more
doaj   +1 more source

A descriptive study on epidemiological profile of patients presenting with animal bites at a rural health facility in Uttarakhand, India

open access: yesJournal of Family Medicine and Primary Care
Background: Rabies is a viral disease caused by Lyssavirus type 1, primarily affecting warm-blooded animals, especially carnivores like dogs and cats.
Abhishek Sadasivan   +4 more
doaj   +1 more source

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

open access: yesAdvanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu   +8 more
wiley   +1 more source

A STUDY OF CORRELATION BETWEEN AGENT, HOST, ENVIRONMENT AND VACCINE FACTORS WITH PREVALENCE OF RABIES IN INDONESIA 2015

open access: yesIndonesian Journal of Tropical and Infectious Disease, 2018
A zoonotic disease has been global threat related to health and one of them is rabies. More than 150 countries around the world has infected by rabies disease problem and the case fatality rate (CFR) reaches 100%, which there are 55,000 people died every
Tyas Ika Budi Setyowati   +1 more
doaj   +1 more source

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