Results 11 to 20 of about 22,237 (159)
ANÁLISE IN SILICO EM AQUAPORINA-1 PLAQUETÁRIA MUTANTE E REPERCUSSÕES TROMBOGÊNICAS
Introdução/Objetivos: A aquaporina-1 (AQP1) é um canal regulador osmótico. Faz-se presente em diversas células, como hemácias e plaquetas. Nestas, aprimora a hemostasia intensificando o processo de baloneamento e o estímulo à microvesiculação e ao ...
ARV Prudêncio, W Baleotti-Júnior
doaj +1 more source
The Characteristics of Opportunistic Infections Among AIDS Patiaents in BRSU Tabanan in 2019
According to WHO and UNAIDS report, there has been dramatic increase of HIV/AIDS cases in Indonesia. The objective of the study was to determine the distribution of opportunistic infections in people with HIV / AIDS and the use of antiretroviral drugs in
Putu Prayoga Ratha +1 more
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Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang +7 more
wiley +2 more sources
Genetic characterization of a novel pheasant-origin orthoreovirus using Next-Generation Sequencing
A field isolate (Reo/SDWF /Pheasant/17608/20) of avian orthoreovirus (ARV), isolated from a flock of game-pheasants in Weifang, Shandong Province, was genetically characterized being a field variant or novel strain in our recent research studies in ...
Yi Tang +5 more
doaj +2 more sources
Perception of People Living With HIV/AIDS Affecting Lost to Follow-Up of ARV Therapy
Introduction: HIV/AIDS sufferers must consume antiretrovirals every day and control routinely each month to take ARVs in the hospital. The condition make patients having a risk of lost to follow up attitude. The purpose of this study was to determine the
Lilik Manowati +2 more
doaj +1 more source
People living with HIV/AIDS (PLWHA) can have better health outcomes with early identification of the AIDS phase. In the first three years, PLWHA may progress to the AIDS stage.
Kartika Alifia +4 more
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Synergistic pathogenicity of avian orthoreovirus and Staphylococcus aureus on SPF chickens
: Avian arthritis is a relatively common disease in the poultry industry, the cause of which is complex. Bacterial arthritis is often caused by infection of Staphylococcus aureus (S. aureus), whereas viral arthritis is caused by avian orthoreovirus (ARV).
Xiaoning Jiang +8 more
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Background: Rabies is a viral disease caused by Lyssavirus type 1, primarily affecting warm-blooded animals, especially carnivores like dogs and cats.
Abhishek Sadasivan +4 more
doaj +1 more source
Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
A zoonotic disease has been global threat related to health and one of them is rabies. More than 150 countries around the world has infected by rabies disease problem and the case fatality rate (CFR) reaches 100%, which there are 55,000 people died every
Tyas Ika Budi Setyowati +1 more
doaj +1 more source

