Results 31 to 40 of about 22,237 (159)

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Evaluation of valve function in antireflux biliary metal stents

BMC Gastroenterology, 2018
Background To overcome duodenobiliary reflux induced by biliary stents, antireflux valve (ARV) biliary stents have been developed and showed improvement in stent patency.
Chang-Il Kwon, Jong Pil Moon, Ho Yun, Seok Jeong, Dong Hee Koh, Woo Jung Lee, Kwang Hyun Ko, Dae Hwan Kang   +7 more
doaj   +1 more source

Potential contribution of biomass gasification‐based technology in energy transition: a technical review coupled with bibliometric studies

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biomass gasification technology has been extensively researched around the world; however, there is a need to evaluate the current research landscape and evolutionary direction of research in the broader context of energy transition. A systematic bibliometric analysis of the Web of Science database was performed for articles that fall within ...
Olasunkanmi Opeoluwa Adeoye, Electo Eduardo Silva Lora, Rubenildo Vieira Andrade, Leonardo Peña Pupo, René Lesme Jaén, Osvaldo José Venturini   +5 more
wiley   +1 more source

Effect of esomeprazole on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader, in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this study is to evaluate the effects of multiple doses of esomeprazole, a strong proton pump inhibitor and acid‐reducing agent, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader.
Lana Tran, Naihan Chen, Jennifer A. Winton, Kyle T. Matschke, Smita P. Goodman, Kimberly C. Lee, Yuanyuan Zhang, Weiwei Tan   +7 more
wiley   +1 more source

Mechanisms and Management of Acquired Aseptic Intracardiac Communications After Transcatheter Aortic Valve Implantation: Single‐Center Case Series Insights

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Acquired aseptic intracardiac communications (AICCs) are rare but clinically relevant structural complications following transcatheter aortic valve implantation (TAVI), typically resulting from mechanical injury to the aortic annulus, interventricular septum, or adjacent structures.
Geza Fontos, Abdelkrim Ahres, Marton Vertesaljai, Tunde Pinter, Zsolt Piroth, Matyas Pal, Peter Andreka   +6 more
wiley   +1 more source

Primary local wound management practices and initiation of post-exposure prophylaxis among animal bite victims in a teaching institution hospital of Central India

Journal of Family Medicine and Primary Care
Context: Rabies is associated with sociocultural practices and myths leading to ineffective management of wound due to animal bite among the victims making it prime importance in the field of primary health care.
Arindam Maiti, Arvind Sharma, Sunita Patel, Ashish Mishra   +3 more
doaj   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

2432

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: Effective HIV therapeutic options for persons with advanced HIV disease whose regimens have failed multiple times are limited. Current clinical practice utilizes regimens comprised of combinations of anti-retroviral (ARV) drugs.
Yuan Huang, Sheldon T. Brown, Shuangge Ma, Tassos Kyriakides   +3 more
doaj   +1 more source

Explore how immobilization strategies affected immunosensor performance by comparing four methods for antibody immobilization on electrode surfaces

Scientific Reports, 2022
Among the common methods used for antibody immobilization on electrode surfaces, which is the best available option for immunosensor fabrication? To answer this question, we first used graphene-chitosan-Au/Pt nanoparticle (G-Chi-Au/PtNP) nanocomposites ...
Jiaoling Huang, Zhixun Xie, Liji Xie, Sisi Luo, Tingting Zeng, Yanfang Zhang, Minxiu Zhang, Sheng Wang, Meng Li, You Wei, Qing Fan, Zhiqin Xie, Xianwen Deng, Dan Li   +13 more
doaj   +1 more source

An in vitro comparison of PDGF‐BB release from composite graft materials containing leukocyte‐rich platelet‐rich fibrin and platelet‐derived growth factor‐BB and β‐tricalcium phosphate

Journal of Periodontology, EarlyView.
Abstract Background The clinical efficacy of growth factors in regenerative procedures may depend on both dosage and sustained delivery during critical phases of healing. This study aimed to evaluate in vitro release kinetics of platelet‐derived growth factor‐BB (PDGF‐BB) from various graft materials, including recombinant human PDGF‐BB (rhPDGF‐BB ...
Farahnaz Fahimipour, Maggie A. Misch‐Haring, Ramzi V. Abou Arraj, Nicolaas C. Geurs, Maria L. Geisinger   +4 more
wiley   +1 more source