Results 151 to 160 of about 17,003 (187)
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Induction of aryl hydrocarbon hydroxylase activity and pulmonary carcinoma
International Journal of Cancer, 1979AbstractAryl hydrocarbon hydroxylase activity in lymphoblasts from normal Finnish adults and from patients with pulmonary carcinomas and other types of malignancy has been studied by a modification of previously used techniques. High absolute induced aryl hydrocarbon hydroxylase activity was found in 39% of patients with untreated lung cancer but only ...
Timo U. Kosunen+4 more
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, 1991
Relative aryl hydrocarbon hydroxylase (AHH) induction potencies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the two coplanar PCB congeners 3,3′,4,4′-tetrachlorobiphenyl (IUPAC congener 77) and 3,3′,4,4′,5-pentachlorobiphenyl (IUPAC congener 126 ...
D. Janz, C. Metcalfe
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Relative aryl hydrocarbon hydroxylase (AHH) induction potencies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the two coplanar PCB congeners 3,3′,4,4′-tetrachlorobiphenyl (IUPAC congener 77) and 3,3′,4,4′,5-pentachlorobiphenyl (IUPAC congener 126 ...
D. Janz, C. Metcalfe
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Aryl hydroxylase induction in the chick embryo by polycyclic hydrocarbons
Biochimica et Biophysica Acta (BBA) - General Subjects, 1973Abstract The ability of various polycyclic hydrocarbons to induce liver microsomal enzzmes which convert 7,12-[ 14 C ] dimethylbenz (a) anthracene to water-soluble products was compared in the chick embryo and the rat. A good correlation in response to the 18 hydrocarbons tested was obtained but the chick embryo was found to provide a
Gillian P. Smith, Peter H. Jellinck
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Flavone Modulators of Rat Hepatic Aryl Hydrocarbon Hydroxylase
Pharmacology, 1985The cytochrome P-450-dependent aryl hydrocarbon hydroxylase (AHH) metabolizes a wide variety of endogenous and exogenous compounds to nontoxic metabolites and/or toxic products. We have utilized a series of 18 flavone modulators of AHH to distinguish and probe for different cytochrome P-450 isozymes in liver microsomes from control and 3 ...
Fred K. Friedman+3 more
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Archives of Biochemistry and Biophysics, 1977
Aryl hydrocarbon hydroxylase (AHH) activity has been demonstrated in the nucleus by a specific histofluorescent technique. The nuclear AHH is present at 15–20% of the activity of the microsomal enzyme. The properties of the nuclear and microsomal AHH have been compared.
Jimmie B. Vaught+5 more
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Aryl hydrocarbon hydroxylase (AHH) activity has been demonstrated in the nucleus by a specific histofluorescent technique. The nuclear AHH is present at 15–20% of the activity of the microsomal enzyme. The properties of the nuclear and microsomal AHH have been compared.
Jimmie B. Vaught+5 more
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Aryl hydrocarbon hydroxylase and psoriasis [PDF]
Sam Shuster, Michael D Rawlins
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Aryl hydrocarbon hydroxylase in persons with lung or laryngeal cancer
International Journal of Cancer, 1978AbstractTo test whether the distribution of AHH inducibility is shifted toward the high end of the range in patients who had lung and laryngeal cancer, we measured this trait in 59 patients (32 lung and 27 laryngeal) who had resectable tumors and had been disease‐free for a period of time.
Ward, E+7 more
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Placental aryl hydrocarbon hydroxylase activity and placental calcifications
Toxicology, 1992Induction of aryl hydrocarbon hydroxylase (AHH) activity in the placenta as a result of maternal exposure to polycyclic aromatic hydrocarbons contained in cigarette smoke has been well documented. Furthermore, calcifications are more prevalent in the placentas of pregnant smokers than in those of non-smokers.
Jean Godin+6 more
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IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor
Nature Immunology, 2021Yuying Liu+26 more
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Beryllium Effects on Aryl Hydrocarbon Hydroxylase in Rat Lung
Archives of Environmental Health: An International Journal, 1973This study was undertaken to determine whether beryllium would interfere with pulmonary mixed function oxidases. Rats were injected intratracheally with 150 μmols/kg of a neutralized solution of beryllium sulfate (BeSO4). The activity of pulmonary aryl hydrocarbon hydroxylase (AHH) was measured one, two, and seven days, and two and four weeks after ...
André Jacques, Hanspeter R. Witschi
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