Results 21 to 30 of about 263,945 (178)

Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation [PDF]

, 2019
Summary: B cell lymphoma-6 (BCL6) is highly expressed in germinal center B cells, but how its expression is maintained is still not completely clear. Aryl hydrocarbon receptor interacting protein (AIP) is a co-chaperone of heat shock protein 90. Deletion
Buckley, Christopher, Aksoy, E., Anna Vossenkämper, Capasso, Melanie, Stopka-Farooqui, U., Urszula Stopka-Farooqui, John Gribben, Stopka-Farooqui, Urszula, Parsonage, Gregory, Parsonage, G., Oliver Haworth, Norris, S., Korbonits, Marta, Haworth, O, Haworth, O., Marshall, Jennifer; id_orcid, Gribben, J, Vossenkämper, A., Aksoy, E, Haworth, Oliver, Stopka-Farooqui, U, Parsonage, G, Buckley, CD, Vossenkamper, A, Gregory Parsonage, Clear, A., Capasso, M, Norris, S, Christopher D. Buckley, Xinyu Wan, Buckley, C., Andrew Clear, Gribben, J., Korbonits, M., Clear, Andrew, Gribben, John, Sherine Norris, Barry, Sayka, MacDonald, TT, Norris, Sherine, Jennifer L. Marshall, Thomas T. MacDonald, Marshall, J., Márta Korbonits, Wan, X, Sun, D, Sun, Dijue, Dijue Sun, Sun, D., MacDonald, T., Wan, X., Barry, S., Sayka Barry, Askoy, Ezra, MacDonald, Thomas T., Melania Capasso, Clear, A, Korbonits, M, Barry, S, Marshall, JL, Wan, Xinyu, Ezra Aksoy, Vossenkamper, Anna, Capasso, M.   +63 more
core   +1 more source

Oxygenaging: A Physiological Framework for Geroscience

Aging Cell, Volume 25, Issue 9, September 2026.
Mechanisms of aging disrupt oxygen homeostasis through three converging processes: oxygen‐cascade impairment, microvascular dysfunction, and molecular maladaptation. “Oxygenaging” integrates these domains to explain how declining oxygen delivery and utilization drive mitochondrial instability and amplify the effect of the hallmarks of aging.
Stefano Donega, Kenneth W. Fishbein, Paolo Dominelli, Allison B. Herman, Rafael de Cabo, Myriam Gorospe, Luigi Ferrucci   +6 more
wiley   +1 more source

Aryl sulfonamides induce degradation of aryl hydrocarbon receptor nuclear translocator through crl4dcaf15 e3 ligase

, 2020
Aryl hydrocarbon receptor nuclear translocator (ARNT) plays an essential role in maintaining cellular homeostasis in response to environmental stress.
Byoung Chul Park, Jung Ae Kim, Min Yeong Yu, Ho Chul Shin, Sunhong Kim, Sung Ah Kim, Seung-Hyun Jo, Jin Hwa Cho, Jeong Hoon Kim, Sung Goo Park   +9 more
core   +1 more source

Proteomic analysis of the rat ovary following chronic low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) [PDF]

, 2009
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a ubiquitously distributed endocrine-disrupting chemical and reproductive toxicant. In order to elucidate low-dose TCDD-mediated effects on reproductive or endocrine functions, female Sprague-Dawley rats were
Chen, Xi, Chun-mei Zhang, Jing Liu, Ma, X.M., Zhang, C.M., Zhao, L.J., Zhang, Chun-mei, Chen, X., Li-jun Zhao, Sun, M., Ma, Xiao-ming, Coenraads, P.J., Tang, N.J., Liu, J., Tang, Nai-jun, Liu, Jing, Zhao, Li-jun, Xi Chen, Pieter-Jan Coenraads, Ma, S.W., Shi-wei Ma, Min Sun, Coenraads, Pieter-Jan, Xiao-ming Ma, Sun, Min, Ma, Shi-wei, Nai-jun Tang   +26 more
core   +2 more sources

Interaction of the Gut Microbiota and the Enteric Nervous System: Implications in Gastrointestinal Disorders Associated With Autism Spectrum Disorder

Autism Research, Volume 19, Issue 8, August 2026.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, restricted interests, and repetitive behaviors. In addition to these core behavioral symptoms, gastrointestinal (GI) disorders are frequently reported, ranging from severe constipation to diarrhea.
Baptiste Ganachaud, María José Mendoza‐León, Justine Marchix, Alonso Fernandez Tello, Catherine Le Berre Scoul, Ma Cecilia Opazo, Michel Neunlist, Claudia A. Riedel, Martial Caillaud, Hélène Boudin   +9 more
wiley   +1 more source

Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand

, 2007
Carbaryl (1-naphthyl-N-methylcarbamate), a widely used carbamate insecticide, induces cytochrome P450 1A gene expression in mammalian cells. This activity is usually mediated by the interaction of the compound with the aryl hydrocarbon receptor. However,
Boronat, S., Casado, Susana, Navas, José María, Piña, B.   +3 more
core   +1 more source

Antioxidant Functions of the Aryl Hydrocarbon Receptor [PDF]

, 2016
The aryl hydrocarbon receptor (AhR) is a transcription factor belonging to the basic helix-loop-helix/PER-ARNT-SIM family. It is activated by a variety of ligands, such as environmental contaminants like polycyclic aromatic hydrocarbons or dioxins, but ...
Cornelia Dietrich, Dietrich, Cornelia
core   +1 more source

Maternal and infant gut microbiome

iMeta, Volume 5, Issue 4, August 2026.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

ARNT (aryl hydrocarbon receptor nuclear translocator)

, 2004
Review on ARNT (aryl hydrocarbon receptor nuclear translocator), with data on DNA, on the protein encoded, and where the gene is ...
Hankinson, O
core   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source