Results 221 to 230 of about 33,261 (251)

Dexlansoprazole is an aryl hydrocarbon receptor agonist

Food and Chemical Toxicology
Dexlansoprazole, a proton pump inhibitor, is commonly used to treat gastro-esophageal reflux disease and erosive esophagitis. The activated aryl hydrocarbon receptor (AhR) functions as a transcription factor by binding to the aryl hydrocarbon response element (AHRE) of its target genes, with cytochrome P450 (CYP) 1A1 being the most well-known target ...
Kuo-Liang Wei, Shan-Chun Chen, Chih-Yi Lin, Yu-Ting Chou, Wei-Tin Kuo, Teik-Wei Chuah, Jyan-Gwo Joseph Su   +6 more
openaire   +2 more sources

Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocators in human adenoid tissue

Auris Nasus Larynx, 2011
The aim of this study was to determine whether aryl hydrocarbon receptor (AhR) and AhR nuclear translocators (ARNTs) are expressed in human adenoid tissue.Paraffin-embedded human adenoid tissue specimens were obtained from eight children with adenoid hypertrophy.
Kazuhiko, Kubo, Mio, Sakaki, Mitsuru, Ohashi, Shizuo, Komune   +3 more
openaire   +2 more sources

Identification of functional aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator in murine splenocytes

Biochemical Pharmacology, 1996
The objective of the present studies was to determine whether the aryl hydrocarbon receptor (AhR) and AhR nuclear translocator (ARNT) protein are present and functional in B6C3F1 (C57BL/6 x C3H) mouse splenocytes. Northern analysis of poly(A) RNA isolated from splenocytes revealed transcripts of approximately 6.6 kb which hybridized to the AhR ...
C E, Williams, R B, Crawford, M P, Holsapple, N E, Kaminski   +3 more
openaire   +2 more sources

Interaction of 7-Alkoxycoumarins with the Aryl Hydrocarbon Receptor

Journal of Natural Products, 2017
The aryl hydrocarbon receptor (AhR) is a transcription factor activated by a vast array of natural and synthetic ligands. It plays a pivotal role in numerous physiological and pathological responses, such as cell proliferation and differentiation, induction of xenobiotic metabolizing enzymes, response to environmental toxins, and several others.
GARGARO, MARCO, EPIFANO, Francesco, FIORITO, SERENA, Taddeo, Vito Alessandro, GENOVESE, SALVATORE, PIRRO, Matteo, TURCO, ANTONELLA, PUCCETTI, Paolo, Schmidt Weber, Carsten B., FALLARINO, Francesca   +9 more
openaire   +4 more sources

Aryl hydrocarbon receptors: diversity and evolution

Chemico-Biological Interactions, 2002
Animals have evolved inducible enzymatic defenses to facilitate the biotransformation and elimination of toxic compounds encountered in the environment. The sensory component of this system consists of soluble receptors that regulate the expression of certain isoforms of cytochrome P450, other enzymes, and transporters in response to environmental ...
openaire   +2 more sources

Clozapine and the aryl hydrocarbon receptor

Journal of Psychopharmacology, 2022
openaire   +2 more sources

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

Immunity, 2022
Steven Gallinger, David Brooks, René Quevedo   +2 more
exaly  

Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor

Cell Host and Microbe, 2021
Peter Elias, Thomas Sutter, Aayushi Uberoi   +2 more
exaly  

The aryl hydrocarbon receptor and the gut–brain axis

Cellular and Molecular Immunology, 2021
FRANCISCO Quintana, João Vitor Mahler, Andreia Barroso   +2 more
exaly  

Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor

Proceedings of the National Academy of Sciences of the United States of America, 2021
Katherine Martin, Sven Pettersson, Elaine Holmes   +2 more
exaly