Results 201 to 210 of about 33,261 (251)

Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes. [PDF]

J Clin Invest
Cros A, Rigamonti A, de Juan A, Coillard A, Rieux-Laucat M, Tabtim-On D, Papillon E, Goudot C, Cepika AM, Banchereau R, Pascual V, Burbage M, Becher B, Segura E.   +13 more
europepmc   +1 more source

Dendritic cell-targeted liposomes for cancer immunotherapy via inhibition of aryl hydrocarbon receptor. [PDF]

J Nanobiotechnology
Zhang CG, Yeh CY, Hsu SY, Prakash M, Abarientos AB, Chiang-Hsieh HM, Lin YY, Ortiz CLD, Yang LW, Liang PH, Wu HC, Lee YL.   +11 more
europepmc   +1 more source

The Aryl Hydrocarbon Receptor in Neurotoxicity: An Intermediator Between Dioxins and Neurons in the Brain. [PDF]

Toxics
Kimura E.
europepmc   +1 more source

The aryl hydrocarbon receptor system [PDF]

Drug Metabolism and Drug Interactions, 2012
Abstract The aryl hydrocarbon receptor (AhR) recognizes a large number of xenobiotics, such as polyaromatic hydrocarbons (PAHs) and dioxins, and it activates several metabolic and detoxification pathways. Recent evidence suggests that this receptor also has important endogenous functions subsequent to activation by natural dietary ...
Robert Barouki, Martine Aggerbeck, Xavier Coumoul   +2 more
exaly   +3 more sources

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Aryl hydrocarbon receptor and colitis

Seminars in Immunopathology, 2013
The aryl hydrocarbon receptor (AhR), a transcription factor activated by a large variety of natural and synthetic ligands, has recently become the object of great interest among researchers since it represents an important link between environment and immune-mediated pathologies.
MONTELEONE, IVAN, PALLONE, FRANCESCO, MONTELEONE, GIOVANNI   +2 more
openaire   +3 more sources

The aryl hydrocarbon receptor in immunity

Trends in Immunology, 2009
Low-molecular-weight chemicals or xenobiotics might contribute to the increasing prevalence of allergies and autoimmunity. Certain chemicals can alter immune responses via their action on the cytosolic transcription factor aryl hydrocarbon receptor (AhR).
Charlotte, Esser, Agneta, Rannug, Brigitta, Stockinger   +2 more
openaire   +2 more sources

Sorafenib is an antagonist of the aryl hydrocarbon receptor

Toxicology, 2022
Sorafenib is an orally administered inhibitor of several tyrosine protein kinases. Treatment with sorafenib induces autophagy, which may suppress the growth of hepatocellular carcinoma (HCC) and other cancers. Aryl hydrocarbon receptor (AhR) is activated by xenbiotics and is involved in detoxification, but also plays other physiological roles.
Kuo-Liang Wei, Guan-Lun Gao, Yu-Ting Chou, Chih-Yi Lin, Shan-Chun Chen, Yi-Ling Chen, Hui Qin Choi, Chi-Chia Cheng, Jyan-Gwo Joseph Su   +8 more
openaire   +2 more sources

The aryl hydrocarbon receptor and light

Biological Chemistry, 2006
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been intensively studied with respect to the toxicity of xenobiotics. However, its function in response to light has never been summarized. Here, we provide an overview of AhR activation by light with a focus on the role of tryptophan in light-induced AhR activation.
Agneta, Rannug, Ellen, Fritsche
openaire   +2 more sources

The Aryl Hydrocarbon Receptor in Asthma: Friend or Foe? [PDF]

International Journal of Molecular Sciences, 2020
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has emerged as an important player in asthma control. AhR is responsive to environmental molecules and endogenous or dietary metabolites and regulates innate and adaptive immune responses.
Patricia De Nadai, Odile Poulain-Godefroy, Anne Tsicopoulos   +2 more
exaly   +5 more sources