Results 181 to 190 of about 33,160 (231)

Aryl hydrocarbon receptor in club cells drives Th17-mediated lung injury following inhalation exposure to environmentally persistent free radicals. [PDF]

Redox Biol
Pathak R, Kumar A, Ferrier A, Burk D, Cormier SA.   +4 more
europepmc   +1 more source

Dendritic cell-targeted liposomes for cancer immunotherapy via inhibition of aryl hydrocarbon receptor. [PDF]

J Nanobiotechnology
Zhang CG, Yeh CY, Hsu SY, Prakash M, Abarientos AB, Chiang-Hsieh HM, Lin YY, Ortiz CLD, Yang LW, Liang PH, Wu HC, Lee YL.   +11 more
europepmc   +1 more source

Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes. [PDF]

J Clin Invest
Cros A, Rigamonti A, de Juan A, Coillard A, Rieux-Laucat M, Tabtim-On D, Papillon E, Goudot C, Cepika AM, Banchereau R, Pascual V, Burbage M, Becher B, Segura E.   +13 more
europepmc   +1 more source

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Aryl hydrocarbon receptor and colitis

Seminars in Immunopathology, 2013
The aryl hydrocarbon receptor (AhR), a transcription factor activated by a large variety of natural and synthetic ligands, has recently become the object of great interest among researchers since it represents an important link between environment and immune-mediated pathologies.
MONTELEONE, IVAN, PALLONE, FRANCESCO, MONTELEONE, GIOVANNI   +2 more
openaire   +3 more sources

Sorafenib is an antagonist of the aryl hydrocarbon receptor

Toxicology, 2022
Sorafenib is an orally administered inhibitor of several tyrosine protein kinases. Treatment with sorafenib induces autophagy, which may suppress the growth of hepatocellular carcinoma (HCC) and other cancers. Aryl hydrocarbon receptor (AhR) is activated by xenbiotics and is involved in detoxification, but also plays other physiological roles.
Kuo-Liang Wei, Guan-Lun Gao, Yu-Ting Chou, Chih-Yi Lin, Shan-Chun Chen, Yi-Ling Chen, Hui Qin Choi, Chi-Chia Cheng, Jyan-Gwo Joseph Su   +8 more
openaire   +2 more sources

The aryl hydrocarbon receptor in immunity

Trends in Immunology, 2009
Low-molecular-weight chemicals or xenobiotics might contribute to the increasing prevalence of allergies and autoimmunity. Certain chemicals can alter immune responses via their action on the cytosolic transcription factor aryl hydrocarbon receptor (AhR).
Charlotte, Esser, Agneta, Rannug, Brigitta, Stockinger   +2 more
openaire   +2 more sources

The aryl hydrocarbon receptor and light

Biological Chemistry, 2006
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been intensively studied with respect to the toxicity of xenobiotics. However, its function in response to light has never been summarized. Here, we provide an overview of AhR activation by light with a focus on the role of tryptophan in light-induced AhR activation.
Agneta, Rannug, Ellen, Fritsche
openaire   +2 more sources

Nucleocytoplasmic Shuttling of the Aryl Hydrocarbon Receptor

Journal of Biochemistry, 2000
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that acts in concert with the AhR nuclear translocator (ARNT), and alters gene expression in response to environmental contaminants such as 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD).
T, Ikuta, T, Tachibana, J, Watanabe, M, Yoshida, Y, Yoneda, K, Kawajiri   +5 more
openaire   +2 more sources