Results 1 to 10 of about 66,446 (259)
The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions [PDF]
International Journal of Molecular Sciences, 2021 The aryl-hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates numerous cellular responses. Originally investigated in toxicology because of its ability to bind environmental contaminants, AhR has attracted enormous attention in the field of immunology in the last 20 years.
Ursula Grohmann +2 more
exaly +3 more sources
Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs) [PDF]
International Journal of Molecular Sciences, 2020 The aryl hydrocarbon receptor (AhR) was first identified as the intracellular protein that bound and mediated the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and dioxin-like compounds (DLCs). Subsequent studies show that the AhR plays an important role in maintaining cellular homeostasis and in pathophysiology, and there is ...
Arul Jayaraman +2 more
exaly +3 more sources
« Le Lac » de Lamartine : quels usages pour quels enjeux lorsque l’extrait se substitue à l’œuvre ?
Repères, 2021 This article examines the uses and objectives – prescribed by the institution and recommended by textbooks over the past four decades, but also questioned by teachers on their dedicated websites – of Lamartine’s poem “The Lake” during lessons in the ...
Sylviane Ahr
doaj +1 more source
Clinical and Experimental Obstetrics & Gynecology, 2023 Objectives: Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disease characterized by thrombocytopenia. This review will examine the Notch-aromatic hydrocarbon receptor (AhR)-interleukin-22 (IL-22) signaling pathway regulatory mechanisms ...
Qian-qian Fan, Rong-xia He
doaj +1 more source
Gut Microbes, 2022 Alterations in brain/gut/microbiota axis are linked to Irritable Bowel Syndrome (IBS) physiopathology. Upon gastrointestinal infection, chronic abdominal pain and anxio-depressive comorbidities may persist despite pathogen clearance leading to Post ...
Maëva Meynier +21 more
doaj +1 more source
Annals of Tropical Research, 2017 Irrigation for vegetables grown under protected cropping is very important for optimum production. Likewise, choosing an efficient method of irrigation can save water and labour.
Jessie C. Rom +7 more
doaj +1 more source
Annals of Tropical Research, 2017 Tomato is one of the most profitable crops in the Philippines and is extensively cultivated throughout the world. However, its production faces different pest and disease problems, particularly bacterial wilt which greatly reduces yield.
Ana Linda G. Gorme +6 more
doaj +1 more source
Kynurenine: an oncometabolite in colon cancer
Cell Stress, 2020 Tryptophan is one of the eight essential amino acids that must be obtained from the diet. Interestingly, tryptophan is the least abundant amino acid in most proteins, a large portion of cellular tryptophan is converted into metabolites of the serotonin ...
Niranjan Venkateswaran +1 more
doaj +1 more source
Вавиловский журнал генетики и селекции, 2015 Ortho-aminoazotoluene (OAT) is a potent hepatocarcinogen for most strains of mice. It has previously been shown that OAT application activates the aryl hydrocarbon receptor (Ahr) and the constitutive androstane receptor (Car) in the mouse liver.
N. V. Baginskaya +5 more
doaj +1 more source
Exploring the impact of endogenous AHR ligand, 6-formylindole [3,2-b]carbazole (FICZ) on the microbiota-gut-brain axis in chronic stress-induced depression in rats [PDF]
Trends in Pharmaceutical SciencesAryl hydrocarbon receptor (AHR) is a nuclear receptor that mediates responses to environmental stimuli. The microbiome, influenced by factors such as nutrition, antibiotics, stress, and infection, plays a crucial role in mood, cognition, and mental ...
Najmeh Ekhtiyardar +6 more
doaj +1 more source