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Aryl Hydrocarbon Receptor in Health and Disease [PDF]

MedComm
The aryl hydrocarbon receptor (AhR) functions as a ligand‐dependent transcription factor, serving as a pivotal environmental sensor that significantly influences both physiological and pathological processes.
Haonan Li, Yufeng Fan, Jizheng Liu, Shumin Dong, Bin Wen, Yunfei Zhang, Xiaocui Wang, Xuemei Duan, Ying Hu, Ze Yan, Huifeng Shang, Yukai Jing   +11 more
doaj   +4 more sources

Roles of aryl hydrocarbon receptors in diesel exhaust inhalation-induced cardiopulmonary toxicities during initiation of pulmonary respiration in chicken

环境与职业医学, 2023
BackgroundDue to the limited availability of established research models, very few studies addressed the health effects and underlying mechanisms following exposure to diesel exhaust during the initiation of pulmonary respiration.
Hao NI, Jing JI, Yajie GUO, Shuping ZHONG, Qixiao JIANG   +4 more
doaj   +1 more source

Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway

Biochemistry and Biophysics Reports, 2022
Indigo naturalis, a herbal medicine purified from indigo-containing plants, such as Strobilanthes cusia, Isatis tinctoria, and Polygonum tinctorium, has been reported to be useful in the treatment of ulcerative colitis by activating the aryl hydrocarbon ...
Taka Asari, Hidezumi Kikuchi, Shogo Kawaguchi, Hirotake Sakuraba, Shukuko Yoshida, Yui Akemoto, Takato Maeda, Ota Shinji, Yasuhisa Murai, Naoki Higuchi, Kentaro Hoshi, Yukari Fukutoku, Hiroto Hiraga, Kenroh Sasaki, Shinsaku Fukuda   +14 more
doaj   +1 more source

Vitiligo patients show significant up-regulation of aryl hydrocarbon receptor transcription factor [PDF]

Anais Brasileiros de Dermatologia, 2018
: IL-22 has been implicated in the pathogenesis of vitiligo. However, the role of aryl hydrocarbon receptor transcription factor that acts as a master regulator of IL-22-producing Th22 cells is not fully understood.
Farinaze Behfarjam, Zohreh Jadali
doaj   +1 more source

The role of immune homeostasis in patients with new coronavirus infection (COVID-19) in the development of invasive pulmonary aspergillosis

Журнал инфектологии, 2023
Recently, more attention has been paid to the role of indolamine-2,3-dioxygenase and aryl hydrocarbon receptor in maintaining a balance between immune reactivity and tolerance in various infectious diseases.
A. E. Taraskina, E. V. Frolova, O. V. Shadrivova, O. V. Sekretareva, N. V. Vasilyeva   +4 more
doaj   +1 more source

Aryl hydrocarbon receptor overexpression in miniaturized follicles in female pattern hair loss [PDF]

Anais Brasileiros de Dermatologia, 2017
The etiopathogenesis of female pattern hair loss is still poorly understood. In addition to genetic and hormonal elements, environmental factors could be involved.
Paulo Müller Ramos, Gabrielli Brianezi, Ana Carolina Pereira Martins, Márcia Guimarães da Silva, Mariângela Esther Alencar Marques, Hélio Amante Miot   +5 more
doaj   +2 more sources

Altered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs. [PDF]

PLoS ONE, 2013
The aryl hydrocarbon receptor (AHR) mediates biological responses to toxic chemicals. An unexpected role for AHR in vascularization was suggested when mice lacking AHR displayed impaired closure of the ductus venosus after birth, as did knockout mice for
Frank G van Steenbeek, Bart Spee, Louis C Penning, Anne Kummeling, Ingrid H M van Gils, Guy C M Grinwis, Dik Van Leenen, Frank C P Holstege, Manon Vos-Loohuis, Jan Rothuizen, Peter A J Leegwater   +10 more
doaj   +1 more source

The key player in the pathogenesis of environmental influence of systemic lupus erythematosus: Aryl hydrocarbon receptor

Frontiers in Immunology, 2022
The aryl hydrocarbon receptor was previously known as an environmental receptor that modulates the cellular response to external environmental changes. In essence, the aryl hydrocarbon receptor is a cytoplasmic receptor and transcription factor that is ...
Jingwen Wu, Tianyi Pang, Ziyuan Lin, Ming Zhao, Hui Jin   +4 more
doaj   +1 more source

MIR-320a/b inhibits cell viability and cell cycle progression by targeting aryl hydrocarbon receptor nuclear translocator-like in acute promyelocyte leukaemia

Polish Journal of Pathology, 2022
Acute promyelocyte leukaemia (APL) is a subgroup of acute myeloid leukaemia. Dysregulation of clock genes has been revealed to be involved in APL progression. Herein, the mechanism of clock gene aryl hydrocarbon receptor nuclear translocator- like (ARNTL)
Dan Hu, Zhenji Shen, Lin Yuan
doaj   +1 more source

Increased Expression of Aryl Hydrocarbon Receptor in Peripheral Blood Mononuclear Cells of Patients with Autoimmune Hepatitis

Middle East Journal of Digestive Diseases, 2018
BACKGROUND Previous studies have indicated an elevated level of serum Interleukin (IL)-22 in patients with autoimmune hepatitis (AIH). However, there are no experimental data on the master transcription factor (aryl hydrocarbon receptor) that plays an ...
Farinaz Behfarjam, Zohreh Jadali
doaj   +1 more source