Results 11 to 20 of about 33,160 (231)
The Aryl Hydrocarbon Receptor and Tumor Immunity [PDF]
Frontiers in Immunology, 2018 The aryl hydrocarbon receptor (AhR) is an important cytosolic, ligand-dependent transcription factor. Emerging evidence suggests the promoting role of the AhR in the initiation, promotion, progression, invasion, and metastasis of cancer cells. Studies on
Ping Xue +3 more
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Antioxidant Functions of the Aryl Hydrocarbon Receptor [PDF]
Stem Cells International, 2016 The aryl hydrocarbon receptor (AhR) is a transcription factor belonging to the basic helix-loop-helix/PER-ARNT-SIM family. It is activated by a variety of ligands, such as environmental contaminants like polycyclic aromatic hydrocarbons or dioxins, but ...
Cornelia Dietrich
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NEW TRENDS IN ARYL HYDROCARBON RECEPTOR BIOLOGY [PDF]
Frontiers in Cell and Developmental Biology, 2016 Traditionally considered as a critical intermediate in the toxic and carcinogenic response to dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD), the Aryl hydrocarbon/Dioxin receptor (AhR) has proven to be also an important regulator of cell physiology ...
Pedro M. Fernández-Salguero +1 more
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Aryl Hydrocarbon Receptor and Stem Cells
Stem Cells International, 2017 Thomas A. Gasiewicz +2 more
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The aryl hydrocarbon receptor in liver inflammation [PDF]
Seminars in Immunopathology, 2021 AbstractThe aryl hydrocarbon receptor (AHR) is a ubiquitously expressed ligand-activated transcription factor with multifaceted physiological functions. In the immune system, AHR has been unequivocally identified as a key regulatory factor that can integrate environmental, dietary, or microbial signals into innate and adaptive immune responses ...
Antonella Carambia, Fenja Amrei Schuran
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The aryl hydrocarbon receptor system [PDF]
dmdi, 2012 Abstract The aryl hydrocarbon receptor (AhR) recognizes a large number of xenobiotics, such as polyaromatic hydrocarbons (PAHs) and dioxins, and it activates several metabolic and detoxification pathways. Recent evidence suggests that this receptor also has important endogenous functions subsequent to activation by natural dietary ...
Barouki, Robert +3 more
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Aryl Hydrocarbon Receptor Mechanisms Affecting Chronic Kidney Disease
Frontiers in Pharmacology, 2022 The aryl hydrocarbon receptor (AHR) is a basic helix-loop-helix transcription factor that binds diverse endogenous and xenobiotic ligands, which regulate AHR stability, transcriptional activity, and cell signaling.
Colleen S. Curran, Jeffrey B. Kopp
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Potential role of PM2.5 in melanogenesis
Environment International, 2019 Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals.
Fen Peng +4 more
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Aryl Hydrocarbon Receptor: From Homeostasis to Tumor Progression
Frontiers in Cell and Developmental Biology, 2022 Transcription factor aryl hydrocarbon receptor (AHR) has emerged as one of the main regulators involved both in different homeostatic cell functions and tumor progression.
Claudia Rejano-Gordillo +5 more
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Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. [PDF]
PLoS ONE, 2013 The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates many of the biological and toxicological actions of structurally diverse chemicals.
Qin Hu +10 more
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