The complex biology of aryl hydrocarbon receptor activation in cancer and beyond
Biochemical Pharmacology, 2023 Graphical abstract The complex biology of AHR activation in cancer and beyond. Graphical abstract depicts the contributing factors to AHR's context specificity. Created with BioRender.com (agreement number: HI25TPR0Z5)
C. Opitz +3 more
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eLife, 2020 Systemic metabolic reprogramming induced by infection exerts profound, pathogen-specific effects on infection outcome. Here, we detail the host immune and metabolic response during sickness and recovery in a mouse model of malaria.
Michelle M Lissner +7 more
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Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor. [PDF]
PLoS ONE, 2014 Azole antifungal ketoconazole (KET) was demonstrated to activate aryl hydrocarbon receptor (AhR). Since clinically used KET is a racemic mixture of two cis-enantiomers (2R,4S)-(+)-KET and (2S,4R)-(-)-KET, we examined the effects of KET enantiomers on AhR
Aneta Novotna +8 more
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Nature Medicine, 2016 Astrocytes have important roles in the central nervous system (CNS) during health and disease. Through genome-wide analyses we detected a transcriptional response to type I interferons (IFN-Is) in astrocytes during experimental CNS autoimmunity and also ...
Veit Rothhammer +21 more
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OSSERVAZIONI SULL’ATTIVAZIONE DEL RECETTORE ARILICO (AHR) IN CORRELAZIONE ALLA CONTAMINAZIONE AMBIENTALE DA METALLI PESANTI IN TUMORI SPONTANEI DI CANI DELLA REGIONE CAMPANIA. Correlation between Aryl hydrocarbon Receptor (AhR ) expression and environmental heavy metals contamination in canine tumors. [PDF]
, 2010 Osservazioni sull’attivazione del recettore arilico (Ahr) in correlazione alla contaminazione ambientale da metalli pesanti in tumori spontanei di cani della regione Campania.
Trapani, Francesca
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The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis
Cell Reports, 2018 Summary: Zebrafish have a high capacity to replace lost neurons after brain injury. New neurons involved in repair are generated by a specific set of glial cells, known as ependymoglial cells.
Rossella Di Giaimo +17 more
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Aryl hydrocarbon receptor: The master regulator of immune responses in allergic diseases
Frontiers in Immunology, 2022 The aryl hydrocarbon receptor (AhR) is a widely studied ligand-activated cytosolic transcriptional factor that has been associated with the initiation and progression of various diseases, including autoimmune diseases, cancers, metabolic syndromes, and ...
Farooq Riaz, Fan Pan, P. Wei
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AIP (aryl hydrocarbon receptor interacting protein) [PDF]
, 2013 Review on AIP (aryl hydrocarbon receptor interacting protein), with data on DNA, on the protein encoded, and where the gene is ...
Korbonits, M, Barry, S
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NEW TRENDS IN ARYL HYDROCARBON RECEPTOR BIOLOGY
Frontiers in Cell and Developmental Biology, 2016 Traditionally considered as a critical intermediate in the toxic and carcinogenic response to dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD), the Aryl hydrocarbon/Dioxin receptor (AhR) has proven to be also an important regulator of cell physiology ...
Pedro M. Fernández-Salguero +1 more
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Regulation of the immune response by the aryl hydrocarbon receptor
Immunity, 2018 The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is activated by small molecules provided by the diet, microorganisms, metabolism and pollutants.
Cristina Gutiérrez-Vázquez +1 more
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