Results 51 to 60 of about 1,542,659 (289)

The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice

Journal of Experimental Medicine, 2022
Eosinophils undergo tissue adaptation in the small intestine. Aryl hydrocarbon receptor–deficient eosinophils fail to induce the full intestinal gene expression program, are functionally impaired in extracellular matrix interactions, are more prone to ...
N. Diny, Barbora Schonfeldova, M. Shapiro, M. Winder, Sunita Varsani-Brown, B. Stockinger   +5 more
semanticscholar   +1 more source

Polycyclic Aromatic Hydrocarbons Affect Rheumatoid Arthritis Pathogenesis via Aryl Hydrocarbon Receptor

Frontiers in Immunology, 2022
Rheumatoid arthritis (RA), the most common autoimmune disease, is characterized by symmetrical synovial inflammation of multiple joints with the infiltration of pro-inflammatory immune cells and increased cytokines (CKs) levels.
Xiaoyu Xi, Xiaoyu Xi, Qinbin Ye, Qinbin Ye, Danping Fan, Danping Fan, Xiaoxue Cao, Xiaoxue Cao, Qiong Wang, Qiong Wang, Xing Wang, Xing Wang, Mengxiao Zhang, Yuan Xu, Cheng Xiao, Cheng Xiao   +15 more
doaj   +1 more source

The Aryl Hydrocarbon Receptor and Tumor Immunity

Frontiers in Immunology, 2018
The aryl hydrocarbon receptor (AhR) is an important cytosolic, ligand-dependent transcription factor. Emerging evidence suggests the promoting role of the AhR in the initiation, promotion, progression, invasion, and metastasis of cancer cells. Studies on
Ping Xue, Jinrong Fu, Yufeng Zhou, Yufeng Zhou   +3 more
doaj   +1 more source

Honeybee gut Lactobacillus modulates host learning and memory behaviors via regulating tryptophan metabolism

Nature Communications, 2022
Eusocial honeybee is a versatile model for neurobiological research. Here, the authors established a link between honeybee gut Lactobacillus in bee learning and memory ability via indole derivatives that activate host’s aryl hydrocarbon receptor.
Zijing Zhang, Xiaohuan Mu, Qina Cao, Yao Shi, Xiaosong Hu, Hao Zheng   +5 more
doaj   +1 more source

The aryl hydrocarbon receptor as a target of environmental stressors – Implications for pollution mediated stress and inflammatory responses

Redox Biology, 2020
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) 1A1 and CYP1A2, which are important enzymes in metabolism of xenobiotics ...
C. Vogel, L. V. Van Winkle, C. Esser, T. Haarmann-Stemmann   +3 more
semanticscholar   +1 more source

Aryl hydrocarbon receptor activation by Lactobacillus reuteri tryptophan metabolism alleviates Escherichia coli-induced mastitis in mice

PLoS Pathogens, 2021
The intestinal microbiota has been associated with the occurrence and development of mastitis, which is one of the most serious diseases of lactating women and female animals, but the underlying mechanism has not yet been elucidated.
Cai-Jun Zhao, Xiao-Yu Hu, Li-Juan Bao, Keyi Wu, Lian-Jun Feng, Min Qiu, Haoyang Hao, Yun-He Fu, Nai-Sheng Zhang   +8 more
semanticscholar   +1 more source

Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation [PDF]

, 2019
Summary: B cell lymphoma-6 (BCL6) is highly expressed in germinal center B cells, but how its expression is maintained is still not completely clear. Aryl hydrocarbon receptor interacting protein (AIP) is a co-chaperone of heat shock protein 90. Deletion
Buckley, Christopher, Aksoy, E., Anna Vossenkämper, Capasso, Melanie, Stopka-Farooqui, U., Urszula Stopka-Farooqui, John Gribben, Stopka-Farooqui, Urszula, Parsonage, Gregory, Parsonage, G., Oliver Haworth, Norris, S., Korbonits, Marta, Haworth, O, Haworth, O., Marshall, Jennifer; id_orcid, Gribben, J, Vossenkämper, A., Aksoy, E, Haworth, Oliver, Stopka-Farooqui, U, Parsonage, G, Buckley, CD, Vossenkamper, A, Gregory Parsonage, Clear, A., Capasso, M, Norris, S, Christopher D. Buckley, Xinyu Wan, Buckley, C., Andrew Clear, Gribben, J., Korbonits, M., Clear, Andrew, Gribben, John, Sherine Norris, Barry, Sayka, MacDonald, TT, Norris, Sherine, Jennifer L. Marshall, Thomas T. MacDonald, Marshall, J., Márta Korbonits, Wan, X, Sun, D, Sun, Dijue, Dijue Sun, Sun, D., MacDonald, T., Wan, X., Barry, S., Sayka Barry, Askoy, Ezra, MacDonald, Thomas T., Melania Capasso, Clear, A, Korbonits, M, Barry, S, Marshall, JL, Wan, Xinyu, Ezra Aksoy, Vossenkamper, Anna, Capasso, M.   +63 more
core   +1 more source

Regulation of Intestinal Stem Cell Stemness by the Aryl Hydrocarbon Receptor and Its Ligands

Frontiers in Immunology, 2021
Maintenance of intestinal homeostasis requires the integration of immunological and molecular processes together with environmental, diet, metabolic and microbial cues.
Paul J. Wisniewski, Mitzi Nagarkatti, Prakash S. Nagarkatti   +2 more
doaj   +1 more source

Targeting Aryl Hydrocarbon Receptor Signaling Enhances Type I Interferon-Independent Resistance to Herpes Simplex Virus

Microbiology Spectrum, 2021
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcript factor that plays an important role in regulating immunity and cell differentiation. However, its role in cell-autonomous antiviral resistance has not been fully elucidated.
Jincheng Chen, Juan Liang, Hui Xu, Wenqi Liu, Shuyan Liu, Lian Duan, Fang Li, Zhaoqin Wang, Yingxia Liu, Brian McSharry, Carl G. Feng, Guoliang Zhang   +11 more
doaj   +1 more source

The Aryl Hydrocarbon Receptor (AHR): Peacekeeper of the Skin

International Journal of Molecular Sciences
In the last decade, the aryl hydrocarbon receptor (AHR) has emerged as a critical peacekeeper for the maintenance of healthy skin. The evolutionary conservation of AHR implied physiological functions for this receptor, beyond the detoxification of man ...
H. Dawe, P. Di Meglio
semanticscholar   +1 more source