Results 31 to 40 of about 98,913 (262)

Nonulcerated Necrobiosis Lipoidica Successfully Treated with Tapinarof: A Case Report

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Samantha J Palomares, Aaron S Farberg Bare Dermatology, Dallas, TX, USACorrespondence: Aaron S Farberg, Tel +1 847 721 2725, Email aaron.farberg@gmail.comAbstract: Necrobiosis lipoidica (NL) is a chronic granulomatous disorder of the skin which usually ...
Palomares SJ, Farberg AS
doaj  

Design and production of stable variants of the structured domains of the transcription factor AhR (Aryl hydrocarbon Receptor)

open access: yes, 2022
reservedIl recettore AhR (“Aryl hydrocarbon Receptor”), appartenente alla superfamiglia di fattori di trascrizione bHLH-PAS, è in grado di mediare, attraverso differenti meccanismi molecolari, una risposta specifica a diversi fattori ambientali o ...
DAMUZZO, MANUELE
core  

NcoA2-Dependent Inhibition of HIF-1 alpha Activation Is Regulated via AhR

open access: yes, 2017
High endogenous levels of aryl hydrocarbon receptor (AhR) contribute to hypoxia signaling pathway inhibition following exposure to the potent AhR ligand benzo[a]pyrene (B[a]P) and could alter cellular homeostasis and disease condition.
康照洲   +1 more
core   +1 more source

Dynamics of REL, RELA and IRF1 transcription factor expression in U937 macrophages after dioxin exposure

open access: yesВавиловский журнал генетики и селекции, 2017
The aryl hydrocarbon receptor (AhR), a ligand- activated transcription factor, participates in a wide range of critical cellular events in response to endogenous signals or xenobiotic chemicals. 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD) is one of the
E. V. Kashina   +5 more
doaj   +1 more source

piRNA-associated proteins and retrotransposons are differentially expressed in murine testis and ovary of aryl hydrocarbon receptor deficient mice [PDF]

open access: yesOpen Biology, 2016
Previous studies suggested that the aryl hydrocarbon receptor (AhR) contributes to mice reproduction and fertility. However, the mechanisms involved remain mostly unknown.
Eva M. Rico-Leo   +16 more
doaj   +1 more source

Proton Pump Inhibitors Increase the Risk of Autoimmune Diseases: A Nationwide Cohort Study

open access: yesFrontiers in Immunology, 2021
BackgroundPrevious study revealed proton pump inhibitors (PPIs) have an effect on gut microbiota. Alteration of the microbiome causes changes of the host immune system and then induces the development of autoimmune diseases (ADs).
Sheng-Hong Lin   +19 more
doaj   +1 more source

Endogenous regulation of the Akt pathway by the aryl hydrocarbon receptor (AhR) in lung fibroblasts

open access: yesScientific Reports, 2021
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor known to mediate toxic responses to dioxin. However, the role of the AhR in the regulation of cellular physiology has only recently been appreciated, including its ability to ...
Fangyi Shi   +5 more
doaj   +1 more source

More than Meets the Eye: The Aryl Hydrocarbon Receptor is an Environmental Sensor, Physiological Regulator and a Therapeutic Target in Ocular Disease

open access: yesFrontiers in Toxicology, 2022
The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor originally identified as an environmental sensor of xenobiotic chemicals.
Christine L. Hammond   +5 more
doaj   +1 more source

Cancer-promoting and Inhibiting Effects of Dietary Compounds: Role of the Aryl Hydrocarbon Receptor (AhR) [PDF]

open access: yes
Polyaromatic hydrocarbons, heterocyclic aromatic amines and dioxin-like compounds are environmental carcinogens shown to initiate cancer in a number of tissue types including prostate and breast.

core   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

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