Results 121 to 130 of about 1,001 (167)
Some of the next articles are maybe not open access.
Diagnosis of arylsulfatase A deficiency
American Journal of Medical Genetics, 1992AbstractMetachromatic leukodystrophy (MLD) is a neurologically devastating autosomal recessive disorder in humans associated with deficient arylsulfatase A activity. However, clinically normal individuals described as being pseudo‐arylsulfatase‐A deficient also demonstrate the same deficiency.
Patricia L. Chang +2 more
openaire +3 more sources
The purification of arylsulfatases A and B
Biochemical Medicine, 1984Abstract Arylsulfatases A and B (arylsulfate sulfohydrolase, EC 3.1.6.1) are isoenzymatical. Both enzymes are located mainly in the liver, though they are widely distributed in mammalian tissues [rabbit liver (1), ox liver (2), human kidney (3), human brain (4), and human liver (5)].
Kazuo Ohuchi +3 more
openaire +3 more sources
Structure of the arylsulfatase A gene
European Journal of Biochemistry, 1990A 14‐kb genomic clone containing the entire gene of human lysosomal arylsulfatase A was isolated. The arylsulfatase A gene is about 3.2 kb long and has eight exons (103–320 nucleotides in size). All intron–exon splice junctions conformed to the GT/AG consensus sequence.
J. Kreysing +2 more
openaire +3 more sources
International Journal of Biological Macromolecules, 2017
A library of Pseudoalteromonas carrageenovora arylsulfatase mutants was constructed by introducing random mutagenesis using error-prone PCR. After screening, one mutant strain was obtained whose arylsulfatase had improved thermal stability. Protein sequence analysis revealed one amino acid substitution of H260L.
Yanbing Zhu +6 more
openaire +3 more sources
A library of Pseudoalteromonas carrageenovora arylsulfatase mutants was constructed by introducing random mutagenesis using error-prone PCR. After screening, one mutant strain was obtained whose arylsulfatase had improved thermal stability. Protein sequence analysis revealed one amino acid substitution of H260L.
Yanbing Zhu +6 more
openaire +3 more sources
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1979
1. Fairly high activities of arylsulfatase are found in the sperm and mature testes of all the sea urchins studied; Strongylocentrotus intermedius, Strongylocentrotus nudus, Hemicentrotus pulcherrimus and Anthocidaris crassispina, whereas the activities in the ovaries and eggs of these animals are low. 2.
Tsuneo Moriya, Motonori Hoshi
openaire +3 more sources
1. Fairly high activities of arylsulfatase are found in the sperm and mature testes of all the sea urchins studied; Strongylocentrotus intermedius, Strongylocentrotus nudus, Hemicentrotus pulcherrimus and Anthocidaris crassispina, whereas the activities in the ovaries and eggs of these animals are low. 2.
Tsuneo Moriya, Motonori Hoshi
openaire +3 more sources
Arylsulfatase of sea urchin sperm
Developmental Biology, 1980Abstract An arylsulfatase is defined as a lysin of sea urchin sperm from the following evidences. (1) The activity is detected in the sperm of all the sea urchins investigated, and the activity is partially liberated from the cells after the acrosome reaction ( Moriya and Hoshi, 1979 ).
Tsuneo Moriya, Motonori Hoshi
openaire +3 more sources
A new electrophoretic variant of arylsulfatase A
Biochemical Medicine and Metabolic Biology, 1988Previous work in this laboratory has identified electrophoretic variant forms of arylsulfatase A in leucocyte plus platelets. During a study to replicate and extend these findings, a new seven-band variant of arylsulfatase A has been identified. Purified platelets gave a clearer, more distinct electrophoretic banding pattern than the leucocyte and ...
Paul Manowitz +5 more
openaire +3 more sources
The determination of arylsulfatases in biological fluids
Clinica Chimica Acta, 1970Abstract A simple, highly sensitive method for the determination of arylsulfatases in serum, urine, saliva and other biological fluids is described. A procedure is given for the preparation of highly purified 4-methylumbelliferone sulfate, the substrate used in this assay.
B.J. Haverback +3 more
openaire +3 more sources
Choroideremia with leukoencephalopathy and arylsulfatase A pseudodeficiency
Journal of the Neurological Sciences, 1996A 33-year-old male patient was admitted to our hospital because of progressive gait disturbance and involuntary movement of the neck. He showed choroideremia, distal motor neuropathy, and leukoencephalopathy on T2-weighted brain magnetic resonance imaging (MRI).
Satoshi Takenaga +6 more
openaire +3 more sources
Studies on the charge isomers of arylsulfatase A
Biochemical Medicine, 1985Human liver arylsulfatase A was resolved into six fractions by narrow pH range preparative isoelectric focusing. Analytical isoelectric focusing revealed that most enzyme fractions were composed of two adjacent charge isomers. Nevertheless, there was considerable enrichment of charge species which allowed a comparative study of selected properties ...
Katherine K. Tsay +9 more
openaire +3 more sources