Results 1 to 10 of about 3,139 (183)
Matching the Diversity of Sulfated Biomolecules: Creation of a Classification Database for Sulfatases Reflecting Their Substrate Specificity [PDF]
PLoS ONE, 2016 Sulfatases cleave sulfate groups from various molecules and constitute a biologically and industrially important group of enzymes. However, the number of sulfatases whose substrate has been characterized is limited in comparison to the huge diversity of ...
Tristan Barbeyron +2 more
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Fucoidan Sulfatases from Marine Bacterium Wenyingzhuangia fucanilytica CZ1127T
Biomolecules, 2018 Fucoidans belong to a structurally heterogeneous class of sulfated polysaccharides isolated from brown algae. They have a wide spectrum of biological activities.
Artem S Silchenko +2 more
exaly +3 more sources
Identification of Multiple Sulfatase Deficiency (MSD) in newborn screening: A case study [PDF]
Molecular Genetics and Metabolism ReportsA patient with multiple sulfatase deficiency (MSD) was identified through a lysosomal storage disorder enzyme analysis panel, based on a characteristic pattern of reduced activities across multiple sulfatases.
Taraka R. Donti +2 more
doaj +2 more sources
Bone marrow transplantation reverses metabolic alterations in multiple sulfatase deficiency: a case series [PDF]
Communications MedicineBackground Multiple sulfatase deficiency (MSD) is an exceptionally rare neurodegenerative disorder due to the absence or deficiency of 17 known cellular sulfatases.
Nishitha R. Pillai +12 more
doaj +2 more sources
Frontiers in Plant Science, 2015 Many algae are rich sources of sulfated polysaccharides with biological activities. The physicochemical/rheological properties and biological activities of sulfated polysaccharides are affected by the pattern and number of sulfate moieties.
Chai-Ling Ho, Ho Chai-Ling
exaly +3 more sources
Bone marrow transplantation increases sulfatase activity in somatic tissues in a multiple sulfatase deficiency mouse model [PDF]
Communications MedicineBackground Multiple Sulfatase Deficiency (MSD) is an ultra-rare autosomal recessive disorder characterized by deficient enzymatic activity of all known sulfatases. MSD patients frequently carry two loss of function mutations in the SUMF1 gene, encoding a
Maximiliano Presa +10 more
doaj +2 more sources
Sulfatases: Critical Enzymes for Algal Polysaccharide Processing
Frontiers in Plant Science, 2022 Microbial sulfatases are important biocatalysts in the marine environment where they play a key role in the catabolic biotransformation of abundant sulphated algal polysaccharides. The sulphate esters decorating algal polysaccharides, such as carrageenan,
Andrew G. Hettle +2 more
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The Role of Sulfation in Nematode Development and Phenotypic Plasticity
Frontiers in Molecular Biosciences, 2022 Sulfation is poorly understood in most invertebrates and a potential role of sulfation in the regulation of developmental and physiological processes of these organisms remains unclear. Also, animal model system approaches did not identify many sulfation-
Catia Igreja, Ralf J. Sommer
doaj +1 more source
Frontiers in Microbiology, 2022 Chondroitin sulfate (CS)/dermatan sulfate (DS) is a kind of sulfated polyanionic, linear polysaccharide belonging to glycosaminoglycan. CS/DS sulfatases, which specifically hydrolyze sulfate groups from CS/DS oligo-/polysaccharides, are potential tools ...
Lin Wei +10 more
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Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship [PDF]
Human Molecular Genetics, 2005 Sulfatases catalyze the hydrolysis of sulfate ester bonds from a wide variety of substrates. Several human inherited diseases are caused by the deficiency of individual sulfatases, while in patients with multiple sulfatase deficiency mutations in the Sulfatase Modifying Factor 1 (SUMF1) gene cause a defect in the post-translational modification of a ...
SARDIELLO M. +3 more
openaire +4 more sources