Results 1 to 10 of about 18,322 (221)

Research and Application of Chondroitin Sulfate/Dermatan Sulfate-Degrading Enzymes [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
Chondroitin sulfate (CS) and dermatan sulfate (DS) are widely distributed on the cell surface and in the extracellular matrix in the form of proteoglycan, where they participate in various biological processes.
Wenshuang Wang   +3 more
doaj   +5 more sources

Data on cloning, expression and biochemical characteristics of a chondroitin sulfate/dermatan sulfate 4-O-endosulfatase [PDF]

open access: yesData in Brief, 2023
The data shown in this article are related to the published paper entitled “A novel 4-O-endosulfatase with high potential for the structure-function studies of chondroitin sulfate/dermatan sulfate” in Carbohydrate Polymers.
Lin Wei   +9 more
doaj   +2 more sources

Effect of epithelial debridement on human cornea proteoglycans [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2001
Corneal transparency is attributed to the regular spacing and diameter of collagen fibrils, and proteoglycans may play a role in fibrillogenesis and matrix assembly. Corneal scar tissue is opaque and this opacity is explained by decreased ultrastructural
E.S. Soriano   +3 more
doaj   +2 more sources

Preparation and purification of Flavobacterium heparinum chondroitinases AC and B by hydrophobic interaction chromatography [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Flavobacterium heparinum is a soil bacterium that produces several mucopolysaccharidases such as heparinase, heparitinases I and II, and chondroitinases AC, B, C and ABC. The purpose of the present study was to optimize the preparation of F.
J.A.K. Aguiar, Y.M. Michelacci
doaj   +2 more sources

Dermatan Sulfate: Structure, Biosynthesis, and Biological Roles [PDF]

open access: yesBiomolecules
Dermatan sulfate (DS) is a remarkably versatile glycosaminoglycan that plays critical roles across a wide array of biological processes. Its unique structure, characterized by repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and Iduronic
Congcong Chen   +7 more
doaj   +2 more sources

Sequencing the Dermatan Sulfate Chain of Decorin. [PDF]

open access: yesJ Am Chem Soc, 2017
Glycomics represents one of the last frontiers and most challenging in omic analysis. Glycosylation occurs in the endoplasmic reticulum and the Golgi organelle and its control is neither well-understood nor predictable based on proteomic or genomic analysis.
Yu Y   +8 more
europepmc   +4 more sources

Delineation of musculocontractural Ehlers–Danlos Syndrome caused by dermatan sulfate epimerase deficiency [PDF]

open access: yesMolecular Genetics & Genomic Medicine, 2020
Background Musculocontractural Ehlers–Danlos Syndrome (mcEDS) is a rare connective tissue disorder caused by biallelic loss‐of‐function variants in CHST14 (mcEDS‐CHST14) or DSE (mcEDS‐DSE), both of which result in defective dermatan sulfate biosynthesis.
Charlotte K. Lautrup   +12 more
doaj   +2 more sources

Comparative Study of Two Chondroitin Sulfate/Dermatan Sulfate 4-O-Sulfatases With High Identity [PDF]

open access: yesFrontiers in Microbiology, 2019
Chondroitin sulfate/dermatan sulfate (CS/DS) sulfatases are potential tools for structural and functional studies of CD/DS chains. In our previous study, a CS/DS 4-O-endosulfatase (endoVB4SF) was identified from a marine bacterium (Wang et al., 2015 ...
Shumin Wang   +6 more
doaj   +2 more sources

Influence of Propolis-Containing Nonwoven PLGA Dressings on Dermatan and Chondroitin Sulfate Dynamics During Burn-Wound Healing [PDF]

open access: yesPharmaceuticals
Background/Objectives: Burn wounds are complex injuries associated with extensive inflammation, extracellular matrix (ECM) damage, and a high risk of impaired tissue remodeling and scarring.
Kinga Orlińska   +11 more
doaj   +2 more sources

Optimization of High-pressure Enzymatic Hydrolysis for Extraction of Dermatan Sulfate and Analysis of Its Antioxidant Activity

open access: yesShipin gongye ke-ji, 2022
Taking permeate liquid in the process of extracting heparin from porcine intestinal mucosa as raw material, the extraction process of dermatan sulfate was optimized to explore the antioxidant capacity of dermatan sulfate.
Yubao WANG   +9 more
doaj   +1 more source

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