Results 1 to 10 of about 232,697 (206)

Data on cloning, expression and biochemical characteristics of a chondroitin sulfate/dermatan sulfate 4-O-endosulfatase [PDF]

open access: yesData in Brief, 2023
The data shown in this article are related to the published paper entitled “A novel 4-O-endosulfatase with high potential for the structure-function studies of chondroitin sulfate/dermatan sulfate” in Carbohydrate Polymers.
Lin Wei   +9 more
doaj   +3 more sources

Dermatan Sulfate: Structure, Biosynthesis, and Biological Roles [PDF]

open access: yesBiomolecules
Dermatan sulfate (DS) is a remarkably versatile glycosaminoglycan that plays critical roles across a wide array of biological processes. Its unique structure, characterized by repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and Iduronic
Congcong Chen   +7 more
doaj   +2 more sources

Carbohydrate sulfotransferase 14 gene deletion induces dermatan sulfate deficiency and affects collagen structure and bowel contraction. [PDF]

open access: yesPLoS ONE
Dermatan sulfate (DS) is a type of glycosaminoglycan present in the extracellular matrix, and which is related to tissue strength, structure, and healing. Dermatan 4-O-sulfotransferase 1 (D4ST1) is an enzyme that catalyzes the transfer of a sulfate group
Fumiko Ono   +9 more
doaj   +2 more sources

Research and Application of Chondroitin Sulfate/Dermatan Sulfate-Degrading Enzymes [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
Chondroitin sulfate (CS) and dermatan sulfate (DS) are widely distributed on the cell surface and in the extracellular matrix in the form of proteoglycan, where they participate in various biological processes.
Wenshuang Wang   +3 more
doaj   +2 more sources

Delineation of musculocontractural Ehlers–Danlos Syndrome caused by dermatan sulfate epimerase deficiency [PDF]

open access: yesMolecular Genetics & Genomic Medicine, 2020
Background Musculocontractural Ehlers–Danlos Syndrome (mcEDS) is a rare connective tissue disorder caused by biallelic loss‐of‐function variants in CHST14 (mcEDS‐CHST14) or DSE (mcEDS‐DSE), both of which result in defective dermatan sulfate biosynthesis.
Charlotte K. Lautrup   +12 more
doaj   +2 more sources

Comparative Study of Two Chondroitin Sulfate/Dermatan Sulfate 4-O-Sulfatases With High Identity [PDF]

open access: yesFrontiers in Microbiology, 2019
Chondroitin sulfate/dermatan sulfate (CS/DS) sulfatases are potential tools for structural and functional studies of CD/DS chains. In our previous study, a CS/DS 4-O-endosulfatase (endoVB4SF) was identified from a marine bacterium (Wang et al., 2015 ...
Shumin Wang   +6 more
doaj   +2 more sources

Bioactive Glycosaminoglycans from Caranx crysos: A Structure–Function Study of Selective Anticoagulant Activity [PDF]

open access: yesMarine Drugs
Glycosaminoglycans (GAGs) are the carbohydrate portion of proteoglycans (PGS), a family of complex biomacromolecules ubiquitously found in the extracellular matrix and on cell surfaces that play critical roles in a plethora of physiological and ...
Ranim Kroumi   +9 more
doaj   +2 more sources

Optimization of High-pressure Enzymatic Hydrolysis for Extraction of Dermatan Sulfate and Analysis of Its Antioxidant Activity

open access: yesShipin gongye ke-ji, 2022
Taking permeate liquid in the process of extracting heparin from porcine intestinal mucosa as raw material, the extraction process of dermatan sulfate was optimized to explore the antioxidant capacity of dermatan sulfate.
Yubao WANG   +9 more
doaj   +1 more source

Novel Insight Into Glycosaminoglycan Biosynthesis Based on Gene Expression Profiles

open access: yesFrontiers in Cell and Developmental Biology, 2021
Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate, except for hyaluronan that is a free polysaccharide, are covalently attached to core proteins to form proteoglycans.
Yi-Fan Huang   +2 more
doaj   +1 more source

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