Results 1 to 10 of about 76,553 (211)

Cell Density-Dependent Suppression of Perlecan and Biglycan Expression by Gold Nanocluster in Vascular Endothelial Cells [PDF]

Cells
Proteoglycans are macromolecules consisting of a core protein and one or more glycosaminoglycan side chains. Proteoglycans synthesized by vascular endothelial cells modulate various functions such as anticoagulant activity and vascular permeability.
Takato Hara, Misato Saeki, Misaki Shirai, Yuichi Negishi, Chika Yamamoto, Toshiyuki Kaji   +5 more
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Testing if Micro-CT Is Capable of Quantitating the Extent of Proteoglycan-Aggrecan Induced Axial Spondyloarthritis in Mice

Frontiers in Immunology, 2021
ObjectiveInjections of proteoglycan aggrecan (PGA) have been reported to induce axial spondyloarthritis (ax-SpA) in BALB/c mice. It is considered to be a model for radiographic ax-SpA.
Qing Han, Qing Han, ZhaoHui Zheng, ZhaoHui Zheng, Qiang Liang, Qiang Liang, Kui Zhang, Kui Zhang, FengFan Yang, FengFan Yang, XiangHui Fu, XiangHui Fu, Xing Luo, Xing Luo, Jin Ding, Jin Ding, Ronghua Xie, Ronghua Xie, WenXiao Zhu, WenXiao Zhu, Ping Zhu, Ping Zhu   +21 more
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An Overview of in vivo Functions of Chondroitin Sulfate and Dermatan Sulfate Revealed by Their Deficient Mice

Frontiers in Cell and Developmental Biology, 2021
Chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS) are covalently attached to specific core proteins to form proteoglycans in their biosynthetic pathways.
Shuji Mizumoto, Shuhei Yamada
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Centennial Review: Trace mineral research with an emphasis on manganeseDedicated to Dr. Roland M. Leach, Jr.

Poultry Science, 2021
: A century of publications in the Poultry Science journal is celebrated with Centennial papers. It is relevant, therefore, to explore trace mineral (TM) research with an emphasis on manganese and selected aspects of skeletal development.
Michael S. Lilburn
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Chondroitin Sulfate as a Potential Modulator of the Stem Cell Niche in Cornea

Frontiers in Cell and Developmental Biology, 2021
Chondroitin sulfate (CS) is an important component of the extracellular matrix in multiple biological tissues. In cornea, the CS glycosaminoglycan (GAG) exists in hybrid form, whereby some of the repeating disaccharides are dermatan sulfate (DS).
Sean Ashworth, Sean Ashworth, Jodie Harrington, Jodie Harrington, Greg M. Hammond, Kiranjit K. Bains, Elena Koudouna, Anthony J. Hayes, James R. Ralphs, Justyn W. Regini, Robert D. Young, Ryuhei Hayashi, Ryuhei Hayashi, Kohji Nishida, Clare E. Hughes, Andrew J. Quantock   +15 more
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The Genes Encoding Small Leucine-Rich Proteoglycans Undergo Differential Expression Alterations in Colorectal Cancer, Depending on Tumor Location

Cells, 2021
Small leucine-rich proteoglycans (SLRPs) regulate different processes and undergo significant alterations in various diseases. Colon carcinomas (CCs) are heterogeneous pathologies with important clinical and molecular differences depending on their ...
Maria Pilar Solis-Hernandez, Carla Martín, Beatriz García, Natalia Pérez-López, Yolanda García-Mesa, Sara González-Fernández, Olivia García-Suárez, Jesús Merayo, Iván Fernández-Vega, Luis M. Quirós   +9 more
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Interplay between Cell-Surface Receptors and Extracellular Matrix in Skin

Biomolecules, 2020
Skin consists of the epidermis and dermis, which are connected by a specialized basement membrane—the epidermal basement membrane. Both the epidermal basement membrane and the underlying interstitial extracellular matrix (ECM) created by dermal ...
Svenja Kleiser, Alexander Nyström
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Chondroitin Sulfates Control Invasiveness of the Basal-Like Breast Cancer Cell Line MDA-MB-231 Through ROR1

Frontiers in Oncology, 2022
Extracellular and cell surface chondroitin sulfates (CSs) regulate cancer cell properties, including proliferation and invasion. Thus, it is necessary to understand the mechanisms underlying their roles in cancer.
Satomi Nadanaka, Jun-ichi Tamura, Hiroshi Kitagawa   +2 more
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Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts

Biomolecules, 2020
Fibrosis is a fundamental feature of systemic sclerosis (SSc) and is characterized by excessive accumulation of extracellular matrix components like proteoglycans (PG) or collagens in skin and internal organs.
Thanh-Diep Ly, Ricarda Plümers, Bastian Fischer, Vanessa Schmidt, Doris Hendig, Joachim Kuhn, Cornelius Knabbe, Isabel Faust   +7 more
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Syndecan receptors: pericellular regulators in development and inflammatory disease [PDF]

Open Biology, 2021
The syndecans are the major family of transmembrane proteoglycans, usually bearing multiple heparan sulfate chains. They are present on virtually all nucleated cells of vertebrates and are also present in invertebrates, indicative of a long evolutionary ...
Sandeep Gopal, Samantha Arokiasamy, Csilla Pataki, James R. Whiteford, John R. Couchman   +4 more
doaj   +1 more source