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Proteoglycan form and function: A comprehensive nomenclature of proteoglycans
Matrix Biology, 2015 We provide a comprehensive classification of the proteoglycan gene families and respective protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular location, overall gene/protein homology, and the utilization of ...
Renato V Iozzo, Liliana Schaefer
exaly +5 more sources
Molecular BioSystems, 2012 Proteoglycans (PGs) are among the most structurally complex biomacromolecules in nature. They are present in all animal cells and frequently exert their critical biological functions through interactions with protein ligands and receptors.
Lingyun Li, Mellisa Ly, R. Linhardt
semanticscholar +3 more sources
Cell Density-Dependent Suppression of Perlecan and Biglycan Expression by Gold Nanocluster in Vascular Endothelial Cells [PDF]
CellsProteoglycans are macromolecules consisting of a core protein and one or more glycosaminoglycan side chains. Proteoglycans synthesized by vascular endothelial cells modulate various functions such as anticoagulant activity and vascular permeability.
Takato Hara +5 more
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Frontiers in Immunology, 2021 ObjectiveInjections of proteoglycan aggrecan (PGA) have been reported to induce axial spondyloarthritis (ax-SpA) in BALB/c mice. It is considered to be a model for radiographic ax-SpA.
Qing Han +21 more
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Frontiers in Cell and Developmental Biology, 2021 Chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS) are covalently attached to specific core proteins to form proteoglycans in their biosynthetic pathways.
Shuji Mizumoto, Shuhei Yamada
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Poultry Science, 2021 : A century of publications in the Poultry Science journal is celebrated with Centennial papers. It is relevant, therefore, to explore trace mineral (TM) research with an emphasis on manganese and selected aspects of skeletal development.
Michael S. Lilburn
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Chondroitin Sulfate as a Potential Modulator of the Stem Cell Niche in Cornea
Frontiers in Cell and Developmental Biology, 2021 Chondroitin sulfate (CS) is an important component of the extracellular matrix in multiple biological tissues. In cornea, the CS glycosaminoglycan (GAG) exists in hybrid form, whereby some of the repeating disaccharides are dermatan sulfate (DS).
Sean Ashworth +15 more
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Seminars in Cell & Developmental Biology, 2001 The predominant proteoglycan present in cartilage is the large chondroitin sulfate proteoglycan 'aggrecan'. Following its secretion, aggrecan self-assembles into a supramolecular structure with as many as 50 monomers bound to a filament of hyaluronan.
C B, Knudson, W, Knudson
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Cells, 2021 Small leucine-rich proteoglycans (SLRPs) regulate different processes and undergo significant alterations in various diseases. Colon carcinomas (CCs) are heterogeneous pathologies with important clinical and molecular differences depending on their ...
Maria Pilar Solis-Hernandez +9 more
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Intracellular proteoglycans [PDF]
Biochemical Journal, 2004 Proteoglycans (PGs) are proteins with glycosaminoglycan chains, are ubiquitously expressed and have a wide range of functions. PGs in the extracellular matrix and on the cell surface have been the subject of extensive structural and functional studies.
Svein Olav, Kolset +2 more
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