Results 1 to 10 of about 82,646 (203)

The Effect of Geranium Leaf Essential oil Pelargonium graveolens on the Expression of MMPs, IL-1β, NO, and PGE2 in Collagenase-induced Arthritis in Rabbits [PDF]

Armaghane Danesh Bimonthly Journal
Background & aim: Chronic diseases, including osteoarthritis, are often debilitating due to their progressive course and affect the quality of life of the elderly.
H Maghsoudi, F Jola, GH Bakhshi Khanegi
doaj  

The Proteoglycans Biglycan and Decorin Protect Cardiac Cells against Irradiation-Induced Cell Death by Inhibiting Apoptosis

Cells
Radiation-induced heart disease (RIHD), a common side effect of chest irradiation, is a primary cause of mortality among patients surviving thoracic cancer. Thus, the development of novel, clinically applicable cardioprotective agents which can alleviate
Renáta Gáspár, Petra Diószegi, Dóra Nógrádi-Halmi, Barbara Erdélyi-Furka, Zoltán Varga, Zsuzsanna Kahán, Tamás Csont   +6 more
doaj   +1 more source

Endosomal signalling via exosome surface TGFβ-1

Journal of Extracellular Vesicles, 2019
Extracellular vesicles such as exosomes convey biological messages between cells, either by surface-to-surface interaction or by shuttling of bioactive molecules to a recipient cell’s cytoplasm.
Ganesh Vilas Shelke, Yanan Yin, Su Chul Jang, Cecilia Lässer, Stefan Wennmalm, Hans Jürgen Hoffmann, Li Li, Yong Song Gho, Jonas Andreas Nilsson, Jan Lötvall   +9 more
doaj   +1 more source

A Systematic Review of Extracellular Matrix-Related Alterations in Parkinson’s Disease

Brain Sciences
The role of the extracellular matrix (ECM) in Parkinson’s disease (PD) is not well understood, even though it is critical for neuronal structure and signaling.
Mary Ann Chapman, Barbara A. Sorg
doaj   +1 more source

Biomimetic strategies for the deputization of proteoglycan functions

Frontiers in Cell and Developmental Biology
Proteoglycans (PGs), which have glycosaminoglycan chains attached to their protein cores, are essential for maintaining the morphology and function of healthy body tissues.
Ibrahim F. Rehan, Ibrahim F. Rehan, Asmaa Elnagar, František Zigo, Ahmed Sayed-Ahmed, Shuhei Yamada   +5 more
doaj   +1 more source

Role of proteoglycan synthesis genes in osteosarcoma stem cells

Frontiers in Oncology
Osteosarcoma stem cells (OSCs) contribute to the pathogenesis of osteosarcoma (OS), which is the most common malignant primary bone tumor. The significance and underlying mechanisms of action of proteoglycans (PGs) and glycosaminoglycans (GAGs) in OSC ...
Ryoma Osumi, Kengo Sugihara, Makoto Yoshimoto, Kazuya Tokumura, Yuki Tanaka, Eiichi Hinoi, Eiichi Hinoi, Eiichi Hinoi   +7 more
doaj   +1 more source

Strength in Weakness: The Mutable Collagenous Tissue of Echinoderms

Encyclopedia
Mutable collagenous tissue (MCT) is a type of connective tissue that is characterized by its capacity to undergo rapid, nervously mediated changes in mechanical properties.
Iain C. Wilkie, M. Daniela Candia Carnevali   +1 more
doaj   +1 more source

Extracellular matrix remodeling therapeutic strategies to tackle central nervous system diseases

Neural Regeneration Research
Neurodegenerative diseases are a global burden due to the increased life expectancy. Neuroinflammation is not only a result of neurodegeneration but a key player in the initiation and onset of it.
Daniel A. Domingo-Lopez, Maria Rosa Aguilar de Armas, Sergio Martin-Saldaña   +2 more
doaj   +1 more source

Proteoglycans in Prostate Cancer Progression and Therapy Resistance

Medicina
The extracellular matrix (ECM) is a complex noncellular network of (macro-)molecules that surrounds and supports diverse cells in tissues and organs.
Ivana Samaržija
doaj   +1 more source

Editorial: Roles of Chondroitin Sulfate and Dermatan Sulfate as Regulators for Cell and Tissue Development

Frontiers in Cell and Developmental Biology, 2022
Shuji Mizumoto, Jessica C. F. Kwok, Jessica C. F. Kwok, John M. Whitelock, Fuchuan Li, Roberto Perris   +5 more
doaj   +1 more source