Results 41 to 50 of about 82,646 (203)

Cytokines and proteoglycans [PDF]

open access: yesExperientia, 1993
Cytokines play an important regulatory role in the metabolism of proteoglycans. Proteoglycans are found in plasma membranes, but predominantly in the extra-cellular matrix. In the latter they are quantitatively and qualitatively essential components. Especially in a tissue like cartilage without any blood vessels, the cells are dependent on cytokines ...
openaire   +2 more sources

Undervalued ubiquitous proteins

open access: yes4 open, 2019
The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Efficient Construction of Atomic-Resolution Models of Non-Sulfated Chondroitin Glycosaminoglycan Using Molecular Dynamics Data

open access: yesBiomolecules, 2020
Glycosaminoglycans (GAGs) are linear, structurally diverse, conformationally complex carbohydrate polymers that may contain up to 200 monosaccharides.
Elizabeth K. Whitmore   +3 more
doaj   +1 more source

An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix. [PDF]

open access: yes, 1995
Agrin is an extracellular matrix (ECM) protein with a calculated relative molecular mass of more than 200 kD that induces the aggregation of acetylcholine receptors (AChRs) at the neuromuscular junction. This activity has been mapped to its COOH terminus.
Ruegg, M. A.   +11 more
core   +1 more source

Mutable Collagenous Tissue: A Concept Generator for Biomimetic Materials and Devices

open access: yesMarine Drugs
Echinoderms (starfish, sea-urchins and their close relations) possess a unique type of collagenous tissue that is innervated by the motor nervous system and whose mechanical properties, such as tensile strength and elastic stiffness, can be altered in a ...
M. Daniela Candia Carnevali   +3 more
doaj   +1 more source

Endocan - a potential diagnostic marker for early onset sepsis in neonates

open access: yesJournal of Infection in Developing Countries, 2019
Introduction: Neonatal early onset sepsis assessment is based on the history of pregnancy and delivery and nonspecific clinical signs. None of the biomarkers currently in use for clinical practice has adequate prognostic value, so it is not possible to ...
Gabriela Ildiko Zonda   +5 more
doaj   +1 more source

大腸菌を用いたフォスファカン(コンドロイチン硫酸プロテオグリカン)の融合コア蛋白の発現条件の検討 [PDF]

open access: yes, 1996
Optimal conditions for expressing a specific region of core protein of phosphacan, a chondroitin sulfate proteoglycan known as receptor type protein tyrosine phosphatase, as fusion protein with glutathione S-transferase (GST) in E.coli were examined. DNA
Ito, Sekiko, Okamoto, Motoi
core   +1 more source

Glycosaminoglycans: Sweet as Sugar Targets for Topical Skin Anti-Aging

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Siew Tein Wang, Boon Hoe Neo, Richard J Betts L’Oréal Research & Innovation, L’Oréal Singapore, SingaporeCorrespondence: Richard J Betts Email richard.betts@rd.loreal.comAbstract: Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of ...
Wang ST, Neo BH, Betts RJ
doaj  

Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease

open access: yesBiomedicines, 2023
Circulating biomarkers reflecting cardiac inflammation are needed to improve the diagnostics and guide the treatment of heart failure patients. The cardiac production and shedding of the transmembrane proteoglycan syndecan-4 is upregulated by innate ...
Mari E. Strand   +10 more
doaj   +1 more source

Carbohydrate-carbohydrate interaction provides adhesion force and specificity for cellular recognition and adhesion [PDF]

open access: yes, 2004
Carbohydrates at the cell surface have been proposed as mediators in cell-cell recognition events involved in embryogenesis, metastasis, and other proliferation processes by calcium-dependent carbohydrate to carbohydrate interactions.
Bucior, Iwona
core   +1 more source

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