Results 51 to 60 of about 82,646 (203)

The Role of Decorin and Biglycan Signaling in Tumorigenesis

open access: yesFrontiers in Oncology, 2021
The complex and adaptive nature of malignant neoplasm constitute a major challenge for the development of effective anti-oncogenic therapies. Emerging evidence has uncovered the pivotal functions exerted by the small leucine-rich proteoglycans, decorin ...
Valentina Diehl   +5 more
doaj   +1 more source

Can proteoglycan change in articular cartilage be detected by ultrasound evaluation? [PDF]

open access: yes, 2013
This paper assesses the capacity of high-frequency ultrasonic waves for detecting changes in the proteoglycan (PG) content of articular cartilage. 50 cartilage-on-bone samples were exposed to ultrasonic waves via an ultrasound transducer at a frequency ...
Singh, Sanjleena   +3 more
core   +1 more source

Chondroitin sulfate proteoglycan and heparan sulfate proteoglycan production by cultured pigeon peritoneal macrophages

open access: yes, 1992
Proteoglycan production was examined in cultures of thioglycollate-elicited peritoneal macrophages obtained from White Carneau and Show Racer pigeons.
William D Wagner, Rick T Owens
core   +1 more source

HSPG2 (heparan sulfate proteoglycan 2) [PDF]

open access: yes, 2009
Review on HSPG2 (heparan sulfate proteoglycan 2), with data on DNA, on the protein encoded, and where the gene is ...
Farach-Carson, MC   +3 more
core   +1 more source

Interaction with proteoglycans enhances the sterol efflux produced by endogenous expression of macrophage apoE

open access: yesJournal of Lipid Research, 2001
Endogenous expression of apolipoprotein (apo)E in macrophages facilitates cholesterol efflux in the presence and absence of extracellular sterol acceptors. A proteoglycan-associated pool of apoE has also been described.
Chen-Yi Lin   +2 more
doaj   +1 more source

Regulation of Macrophage and Dendritic Cell Function by Chondroitin Sulfate in Innate to Antigen-Specific Adaptive Immunity

open access: yesFrontiers in Immunology, 2020
Chondroitin sulfate (CS), a type of glycosaminoglycan (GAG), is a linear acidic polysaccharide comprised of repeating disaccharides, modified with sulfate groups at various positions. Except for hyaluronan (HA), GAGs are covalently bound to core proteins,
Sonoko Hatano, Hideto Watanabe
doaj   +1 more source

Glycosylation of dentin matrix protein 1 is a novel key element for astrocyte maturation and BBB integrity

open access: yesProtein & Cell, 2017
The blood-brain barrier (BBB) is a tight boundary formed between endothelial cells and astrocytes, which separates and protects brain from most pathogens as well as neural toxins in circulation.
Bo Jing   +12 more
doaj   +1 more source

Tissue-specific expression of carbohydrate sulfotransferases drives keratan sulfate biosynthesis in the notochord and otic vesicles of Xenopus embryos

open access: yesFrontiers in Cell and Developmental Biology, 2023
Keratan sulfate (KS) is a glycosaminoglycan that is enriched in vertebrate cornea, cartilage, and brain. During embryonic development, highly sulfated KS (HSKS) is first detected in the developing notochord and then in otic vesicles; therefore, HSKS has ...
Yuuri Yasuoka, Yuuri Yasuoka
doaj   +1 more source

A Reinterpretation of Evidence for the Endothelial Glycocalyx Filtration Structure

open access: yesFrontiers in Cell and Developmental Biology, 2021
The endothelial glycocalyx (eGlx) is thought to be the primary macromolecular filter for fluid flux out of the vasculature. This filter maintains the higher protein concentration within the vessel lumen relative to the tissue.
Kenton P. Arkill
doaj   +1 more source

Application of Proteoglycan from Oreochromis niloticus Cartilage in Silk fibroin/gelatin Scaffold for In vitro Wound Treatment

open access: yesJournal of Health Science and Medical Research (JHSMR), 2015
Objective: To prepare silk fibroin/gelatin scaffold containing epidermal growth factor-like proteoglycan extracted from Oreochromis niloticus cartilage and characterize physical, chemical and biological properties of prepared scaffolds.
Panya Weerawatkapong, Pornanong Aramwit
doaj  

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