Results 51 to 60 of about 84,285 (265)

Intra-individual comparison of human ankle and knee chondrocytes in vitro: relevance for talar cartilage repair [PDF]

, 2009
OBJECTIVE: As compared to knee chondrocytes (KC), talar chondrocytes (TC) have superior synthetic activity and increased resistance to catabolic stimuli. We investigated whether these properties are maintained after TC are isolated and expanded in vitro.
Bonacina, E, Martin, I, Jakob, M, Frueh, J. A., Barbero, A, Bonacina, E., Jakob, M., Heberer, M, Frueh, JA, Wirz, D., Vonwil, D., Barbero, A., Dickinson, S., Martin, I., Candrian, C., Heberer, M., Vonwil, D, Dickinson, SC, Candrian, C, Wirz, D, Vonwil D, Dickinson S, Frueh JA, Martin I, Bonacina E, Jakob M, Heberer M, Barbero A, Wirz D, Candrian C   +29 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Heparan sulfate and cell division

Brazilian Journal of Medical and Biological Research, 1999
Heparan sulfate is a component of vertebrate and invertebrate tissues which appears during the cytodifferentiation stage of embryonic development. Its structure varies according to the tissue and species of origin and is modified during neoplastic ...
Porcionatto M.A., Nader H.B., Dietrich C.P.   +2 more
doaj  

The Effects of Proteoglycan and Type II Collagen on T1ρ Relaxation Time of Articular Cartilage

대한영상의학회지, 2015
Purpose To evaluate the effects of proteoglycan and type II collagen within articular cartilage on T1ρ relaxation time of articular cartilage. Materials and Methods This study was exempted by the institutional and animal review boards, and informed ...
Won Seok Choi, Hye Jin Yoo, Sung Hwan Hong, Ja-Young Choi   +3 more
doaj   +1 more source

Gene expression of proteoglycan core proteins in DM and GAGs treated groups related to control.

, 2014
Gene expression of: agrin, the major GBM proteoglycan; perlecan and collagen XVIII, predominantly mesangial proteoglycans; decorin, a small rich-leucine proteoglycan and glypican-1, a cell suface associated proteoglycan.
André L. Barreira (626480), Carolina Venturotti (626479), Roberto J. C. Fonseca (626482), Rodrigo S. Fortunato (626483), Paulo A. S. Mourão (222876), Gabriela Guimarães (626481), Christina M. Takiya (351905), Conrado L. R. Gomes (626477), Alvimar G. Delgado (626484), Maurilo Leite Jr (335476), Cristina L. Leão (626478)   +10 more
core   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Divergent and co-localization of the two small proteoglycans decorin and proteoglycan-100 in human skeletal tissues and tumors.

, 1993
The core protein of a recently described small proteoglycan, proteoglycan-100, was localized in fetal human tissues by indirect immunocytochemistry and compared with the localization of known members of the small proteoglycan family.
H Kresse, E Vollmer, K Schwarz, A Bosse
core   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Proteoglycan fragments in rabbit joint fluid correlated to arthrosis stage

, 1993
Proteoglycan fragment concentrations in joint fluid of rabbit knees with various degrees of secondary arthrosis after meniscal resection, meniscal substitution, and anterior cruciate ligament transection, were related to the gross appearance of the ...
Lohmander, L. Stefan, Björnsson, Sven, Gillquist, Jan, Messner, Karola   +3 more
core   +1 more source

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

Advanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner, Lennard Spauwen, James L. Martin Robinson, Ángela García Grech, Isabelle Martinier, Sara Grasselli, Aylin Kara Özenler, Matthias Ryma, Jürgen Groll, Mylène de Ruijter, Jos Malda   +10 more
wiley   +1 more source