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Frontiers in Endocrinology, 2021 Diabetic osteoporosis (DOP) belongs to secondary osteoporosis caused by diabetes; it has the characteristics of high morbidity and high disability. In the present study, we constructed a type 1 diabetic rat model and administered chondroitin sulfate (200
Shan Shan Qi +17 more
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Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill [PDF]
Frontiers in Aging, 2021 Discovering compounds that promote health during aging (“geroprotectors”) is key to the retardation of age-related pathologies and the prevention of chronic age-related diseases. In in-silico and model organisms’ lifespan screens, chondroitin sulfate has
Collin Y. Ewald
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Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. [PDF]
PLoS ONE, 2014 The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control ...
Robert D Prinz +3 more
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Data in Brief, 2023 The data shown in this article are related to the published paper entitled “A novel 4-O-endosulfatase with high potential for the structure-function studies of chondroitin sulfate/dermatan sulfate” in Carbohydrate Polymers.
Lin Wei +9 more
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Semi-synthesis of chondroitin sulfate-E from chondroitin sulfate-A [PDF]
Carbohydrate Polymers, 2012 Carbohydrate Polymers, 87, 822-829Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Fuming Zhang +13 more
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Discrepancies in Composition and Biological Effects of Different Formulations of Chondroitin Sulfate
Molecules, 2015 Osteoarthritis is a common, progressive joint disease, and treatments generally aim for symptomatic improvement. However, SYmptomatic Slow-Acting Drugs in Osteoarthritis (SYSADOAs) not only reduce joint pain, but slow structural disease progression.
Johanne Martel-Pelletier +4 more
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Carbohydrate Polymers, 2020 Chondroitin sulfates (CS) account for more than 80% of glycosaminoglycans of articular cartilage, which imparts its physiological functions. We quantified the absolute concentration of the CS components of the full thickness cartilages from the knees of ...
Tzung-Sheng Lin +2 more
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Structural basis for human chondroitin sulfate chain polymerization [PDF]
Nature CommunicationsChondroitin sulfates are complex polysaccharide chains that regulate various biological processes at the cell surface and within the extracellular matrix.
Poushalee Dutta +11 more
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Holothurian Fucosylated Chondroitin Sulfate [PDF]
Marine Drugs, 2014 Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within ...
V. Pomin
semanticscholar +4 more sources
Chondroitin sulfate and joint disease
Osteoarthritis and Cartilage, 1998 SummaryChondroitin sulfate is an important and major component of articular cartilage, where it occurs as part of the large proteoglycan, aggrecan. In the early stages of joint disease, both in animal models and in man, there are change in chondroitin ...
Hardingham, Tim
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