Frontiers in Endocrinology, 2021 Diabetic osteoporosis (DOP) belongs to secondary osteoporosis caused by diabetes; it has the characteristics of high morbidity and high disability. In the present study, we constructed a type 1 diabetic rat model and administered chondroitin sulfate (200
Shan Shan Qi +17 more
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Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. [PDF]
PLoS ONE, 2014 The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control ...
Robert D Prinz +3 more
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Discrepancies in Composition and Biological Effects of Different Formulations of Chondroitin Sulfate
Molecules, 2015 Osteoarthritis is a common, progressive joint disease, and treatments generally aim for symptomatic improvement. However, SYmptomatic Slow-Acting Drugs in Osteoarthritis (SYSADOAs) not only reduce joint pain, but slow structural disease progression.
Johanne Martel-Pelletier +4 more
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Holothurian Fucosylated Chondroitin Sulfate [PDF]
Marine Drugs, 2014 Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within ...
V. Pomin
semanticscholar +4 more sources
Review on Quality Safety Standards and Critical Control Points of Chondroitin Sulfate Sodium
Shipin gongye ke-ji, 2022 Chondroitin sulfate sodium is an acidic mucopolysaccharide extracted from animal cartilage, and has been widely used in the world as anti-osteoarthritis and health food. It is difficult to control the quality and safety of chondroitin sulfate sodium, due
Lin ZHAO +7 more
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A Review of Chondroitin Sulfate’s Preparation, Properties, Functions, and Applications
Molecules, 2023 Chondroitin sulfate (CS) is a natural macromolecule polysaccharide that is extensively distributed in a wide variety of organisms. CS is of great interest to researchers due to its many in vitro and in vivo functions. CS production derives from a diverse
Qingshan Shen +4 more
semanticscholar +1 more source
Preparation, Characterization and in Vitro Bioactivity of Chondroitin Sulfate Chelated Zinc
Shipin gongye ke-ji, 2022 In this paper, the preparation process condition of chondroitin sulfate chelated zinc was optimized by orthogonal test. Chondroitin sulfate and zinc sulfate were selected as the raw materials, chelating rate of zinc as evaluation index, the effects of pH,
Ran GAO +3 more
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Enzymatic Production of Chondroitin Oligosaccharides and Its Sulfate Derivatives
Frontiers in Bioengineering and Biotechnology, 2022 Chondroitin sulfate (CS) has a wide range of physiological functions and clinical applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate derivatives with specific length is always challenging.
Weijiao Zhang +16 more
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Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill
Frontiers in Aging, 2021 Discovering compounds that promote health during aging (“geroprotectors”) is key to the retardation of age-related pathologies and the prevention of chronic age-related diseases. In in-silico and model organisms’ lifespan screens, chondroitin sulfate has
Collin Y. Ewald
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Optimization of Enzyme Assisted Extraction of Chondroitin Sulfate from Bohadschia argus by Response Surface Methodology [PDF]
E3S Web of Conferences, 2021 Chondroitin sulfate is currently one of the bioactive compounds obtained from different natural materials with high benefit in human medical treatment and pharmaceutical. However, the natural concentration of chondroitin sulfate in high cost raw material
Ruensodsai Thanagorn +5 more
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