Results 1 to 10 of about 71,730 (270)

Neuroactive chondroitin sulfate glycomimetics [PDF]

Journal of the American Chemical Society, 2008
We report the generation of chondroitin sulfate (CS) glycomimetics with tunable chemical and biological properties. Our approach greatly simplifies the synthesis of complex glycosaminoglycans, providing synthetically accessible, bioactive structures of ...
Gama, Cristal I., Hsieh-Wilson, Linda C., Matson, John B., Rawat, Manish   +3 more
core   +6 more sources

Review on Quality Safety Standards and Critical Control Points of Chondroitin Sulfate Sodium

Shipin gongye ke-ji, 2022
Chondroitin sulfate sodium is an acidic mucopolysaccharide extracted from animal cartilage, and has been widely used in the world as anti-osteoarthritis and health food. It is difficult to control the quality and safety of chondroitin sulfate sodium, due
Lin ZHAO, Yu JIANG, Tao LAN, Qi WU, Mengyan ZHANG, Xiuwen YIN, Hongyu LIU, Zhenyu YUN   +7 more
doaj   +1 more source

Preparation, Characterization and in Vitro Bioactivity of Chondroitin Sulfate Chelated Zinc

Shipin gongye ke-ji, 2022
In this paper, the preparation process condition of chondroitin sulfate chelated zinc was optimized by orthogonal test. Chondroitin sulfate and zinc sulfate were selected as the raw materials, chelating rate of zinc as evaluation index, the effects of pH,
Ran GAO, Yun SU, Junde CHEN, Meihua ZHENG   +3 more
doaj   +1 more source

Chondroitin Sulfate Alleviates Diabetic Osteoporosis and Repairs Bone Microstructure via Anti-Oxidation, Anti-Inflammation, and Regulating Bone Metabolism

Frontiers in Endocrinology, 2021
Diabetic osteoporosis (DOP) belongs to secondary osteoporosis caused by diabetes; it has the characteristics of high morbidity and high disability. In the present study, we constructed a type 1 diabetic rat model and administered chondroitin sulfate (200
Shan Shan Qi, Shan Shan Qi, Shan Shan Qi, Meng Li Shao, Meng Li Shao, Ze Sun, Ze Sun, Si Min Chen, Ying Jun Hu, Xin Sheng Li, Xin Sheng Li, De Jing Chen, De Jing Chen, Hong Xing Zheng, Hong Xing Zheng, Hong Xing Zheng, Tian Li Yue, Tian Li Yue   +17 more
doaj   +1 more source

Enzymatic Production of Chondroitin Oligosaccharides and Its Sulfate Derivatives

Frontiers in Bioengineering and Biotechnology, 2022
Chondroitin sulfate (CS) has a wide range of physiological functions and clinical applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate derivatives with specific length is always challenging.
Weijiao Zhang, Weijiao Zhang, Weijiao Zhang, Ruirui Xu, Ruirui Xu, Xuerong Jin, Xuerong Jin, Yang Wang, Yang Wang, Litao Hu, Litao Hu, Tianmeng Zhang, Tianmeng Zhang, Guocheng Du, Guocheng Du, Zhen Kang, Zhen Kang   +16 more
doaj   +1 more source

Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill

Frontiers in Aging, 2021
Discovering compounds that promote health during aging (“geroprotectors”) is key to the retardation of age-related pathologies and the prevention of chronic age-related diseases. In in-silico and model organisms’ lifespan screens, chondroitin sulfate has
Collin Y. Ewald
doaj   +1 more source

Optimization of Enzyme Assisted Extraction of Chondroitin Sulfate from Bohadschia argus by Response Surface Methodology [PDF]

E3S Web of Conferences, 2021
Chondroitin sulfate is currently one of the bioactive compounds obtained from different natural materials with high benefit in human medical treatment and pharmaceutical. However, the natural concentration of chondroitin sulfate in high cost raw material
Ruensodsai Thanagorn, Panakkal Elizabeth Jayex, Teerapornnarong Prawpan, Rodiahwati Wawat, Sriariyanun Malinee, Rattanaporn Kittipong   +5 more
doaj   +1 more source

Glycogenes in Oncofetal Chondroitin Sulfate Biosynthesis are Differently Expressed and Correlated With Immune Response in Placenta and Colorectal Cancer

Frontiers in Cell and Developmental Biology, 2021
Oncofetal chondroitin sulfate expression plays an important role in the development of tumors and the pathogenesis of malaria in pregnancy. However, the biosynthesis and functions of these chondroitin sulfates, particularly the tissue-specific regulation
Zi-Yi Wu, Yong-Qiao He, Tong-Min Wang, Da-Wei Yang, Dan-Hua Li, Chang-Mi Deng, Lian-Jing Cao, Jiang-Bo Zhang, Wen-Qiong Xue, Wei-Hua Jia, Wei-Hua Jia   +10 more
doaj   +1 more source

Increased Cerebral Serum Amyloid A2 and Parameters of Oxidation in Arylsulfatase B (N-Acetylgalactosamine-4-Sulfatase)-Null Mice

Journal of Alzheimer's Disease Reports, 2023
Background: Chondroitin sulfate and chondroitin sulfate proteoglycans have been associated with Alzheimer’s disease (AD), and the impact of modified chondroitin sulfates is being investigated in several animal and cell-based models of AD.
Sumit Bhattacharyya, Joanne K. Tobacman
doaj   +1 more source

Comparison of Intravesical Hyaluronic Acid, Chondroitin Sulfate, and Combination of Hyaluronic Acid-Chondroitin Sulfate Therapies in Animal Model of Interstitial Cystitis [PDF]

International Neurourology Journal, 2021
Purpose Three intravesical treatment agents were compared in an interstitial cystitis rat model: chondroitin sulfate, hyaluronic acid, and combined hyaluronic acid-chondroitin sulfate.
Yavuz Onur Danacioglu, Bulent Erol, Seyma Ozkanli, Asif Yildirim, Ramazan Gokhan Atis, Mesrur Selcuk Silay, Turhan Caskurlu   +6 more
doaj   +1 more source