Results 41 to 50 of about 265,373 (265)

Role of chondroitin sulfate in the regulation of neuroimmunoendocrine network interactions in patients with neurological symptoms in the post-covid period

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
The review discusses the prospects for the use of chondroitin sulfate and its derivatives for new indications in patients with and myalgic encephalomyelitis/chronic fatigue syndrome after SARS-CoV-2 infection.
I. V. Sarvilina   +4 more
doaj   +1 more source

Catabolism of chondroitin sulfate

open access: yesCellular and Molecular Biology Letters, 2015
AbstractChondroitin sulfate (CS) is a ubiquitous component of the cell surface and extracellular matrix of animal tissues. CS chains are covalently bound to a core protein to form a proteoglycan, which is involved in various biological events including cell proliferation, migration, and invasion.
openaire   +2 more sources

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu   +13 more
wiley   +1 more source

Role of chondroitin sulfate proteoglycans (CSPGs) in synaptic plasticity and neurotransmission in mammalian spinal cord. [PDF]

open access: yes, 2009
Chronic unilateral hemisection (HX) of the adult rat spinal cord diminishes conduction through intact fibers in the ventrolateral funiculus (VLF) contralateral to HX.
Victor L. Arvanian   +5 more
core  

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Chondroitin sulfate metabolism in the brain [PDF]

open access: yesActa Neurobiologiae Experimentalis, 2020
Over the last twenty years chondroitin sulfate (CS) has become a focus of interest of neuroscience due to its indubitable role in shaping axonal growth, synaptic plasticity and glial scar forming. Various patterns of sulfation give rise to various CS molecules with different properties that are capable of interactions with a plethora of molecules ...
Gręda, Anna, Nowicka, Dorota
openaire   +2 more sources

Extraction of Chondroitin Sulfate from Oncorhynchus and its Analysis [PDF]

open access: yes
In the present study, chondroitin sulfate was extracted from the nasal cartilage of Oncorhynchus mykiss. Chondroitin sulfate derived from Oncorhynchus mykiss had a molecular weight of approximately 150,000. The structural component of chondroitin sulfate,
100000781_ja.html   +4 more
core   +1 more source

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

open access: yesAdvanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner   +10 more
wiley   +1 more source

Chondroitin sulfate alleviates osteoporosis caused by calcium deficiency by regulating lipid metabolism

open access: yesNutrition & Metabolism, 2023
The use of non-drug intervention for calcium deficiency has attracted attention in recent years. Although calcium carbonate is the preferred raw material for calcium supplementation, there are few reports on the mechanism of the combined action of ...
Tianshu Liu   +5 more
doaj   +1 more source

DataSheet1_Enzymatic Production of Chondroitin Oligosaccharides and Its Sulfate Derivatives.docx

open access: yes, 2022
Chondroitin sulfate (CS) has a wide range of physiological functions and clinical applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate derivatives with specific length is always challenging.
Yang Wang (5921)   +7 more
core   +1 more source

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