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Demystifying Heparan Sulfate–Protein Interactions [PDF]
Annual Review of Biochemistry, 2014 Numerous proteins, including cytokines and chemokines, enzymes and enzyme inhibitors, extracellular matrix proteins, and membrane receptors, bind heparin.
Jeffrey Esko, Ding Xu
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Tinkering with heparan sulfate sulfation to steer development
Trends in Cell Biology, 2007Heparan sulfate (HS) proteoglycans, at the cell surface and extracellular matrix, facilitate ligand-receptor interactions crucial to many physiological processes. The distinct sulfation patterns of HS sugar chains presented by their protein core are key to HS proteoglycan activity. Tight regulation of several Golgi complex enzyme families is crucial to
Gorsi, Bushra, Stringer, Sally E.
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Heparan Sulfate Proteoglycans in Amyloidosis
2010Amyloidosis is a generic term for a group of diseases characterized by deposits in different organ systems of insoluble materials composed mainly of distinct fibrillar proteins named amyloid. Besides amyloid, heparan sulfate proteoglycan (HSPG), is commonly found in most amyloid deposits, suggesting that HS/HSPG may be functionally involved in the ...
Xiao, Zhang, Jin-Ping, Li
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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Cell, 2020Kevin Corbett +2 more
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Structure of Heparan Sulfate and Dermatan Sulfate
Annals of the New York Academy of Sciences, 1989openaire +2 more sources
Heparan sulfate proteoglycans as targets for cancer therapy: a review
Cancer Biology and Therapy, 2020Jessica Onyeisi +2 more
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Cell surface heparan sulfate and its roles in assisting viral infections
Medicinal Research Reviews, 2002exaly