Results 31 to 40 of about 41,050 (163)
Poultry Science, 2020 : Adult myoblasts, satellite cells, will proliferate, and differentiate into myotubes in vitro. However, changes in environmental and nutritional conditions will result in the satellite cells differentiating into adipocyte-like cells synthesizing lipids.
Sandra G. Velleman, Cynthia S. Coy
doaj +1 more source
Nature Communications, 2021 Lysosomal storage disorders, characterized by altered metabolism of heparan sulfate, cause autistic symptoms followed by dementia in children. Here, the authors show that embryonic dopaminergic neurodevelopmental defects due to altered function of ...
Maria De Risi +19 more
doaj +1 more source
Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress
Viruses, 2021 Heparan sulfate (HS) and heparan sulfate proteoglycans (HSPGs) are considered important for the entry of many different viruses. Previously, we demonstrated that heparanase (HPSE), the host enzyme responsible for cleaving HS chains, is upregulated by ...
Ghadah A. Karasneh +4 more
doaj +1 more source
Heparin and Heparan Sulfate Biosynthesis [PDF]
IUBMB Life, 2002 AbstractHeparan sulfate is one of the most informationally rich biopolymers in Nature. Its simple sugar backbone is variously modified to different degrees depending on the cellular conditions. Thus, it matures to have an enormously complicated structure, which most likely exhibits a considerable number of unique overlapping sequences with peculiar ...
Kazuyuki, Sugahara, Hiroshi, Kitagawa
openaire +2 more sources
Scientific Reports, 2022 Recent reports demonstrate that SARS-CoV-2 utilizes cell surface heparan sulfate as an attachment factor to facilitate the initial interaction with host cells.
Yulia Kiyan +6 more
doaj +1 more source
Heparan sulfate proteoglycans at a glance [PDF]
Journal of Cell Science, 2007 Proteoglycans are abundant components of the cell surface and extracellular matrix that mediate critical interactions between cells and their environment. They play a variety of biological roles in normal tissues and in response to injury and disease.
Catherine A, Kirkpatrick +1 more
openaire +2 more sources
Heparan Sulfate Biosynthesis in Zebrafish [PDF]
Journal of Histochemistry & Cytochemistry, 2020 The biosynthesis of heparan sulfate (HS) proteoglycans occurs in the Golgi compartment of cells and will determine the sulfation pattern of HS chains, which in turn will have a large impact on the biological activity of the proteoglycans. Earlier studies in mice have demonstrated the importance of HS for embryonic development.
Filipek-Górniok B +3 more
openaire +3 more sources
Heparan Sulfate-Dependent Enhancement of Henipavirus Infection
mBio, 2015 Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus. They infect humans as well as numerous mammalian species.
Cyrille Mathieu +9 more
doaj +1 more source
Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling [PDF]
Brazilian Journal of Medical and Biological Research, 2006 The syndecans, heparan sulfate proteoglycans, are abundant molecules associated with the cell surface and extracellular matrix and consist of a protein core to which heparan sulfate chains are covalently attached. Each of the syndecan core proteins has a
C.C. Lopes, C.P. Dietrich, H.B. Nader
doaj +1 more source
Endothelial Heparan Sulfate in Angiogenesis [PDF]
, 2010 Heparan sulfate (HS) is a linear polysaccharide composed of 50-200 glucosamine and uronic acid (glucuronic acid or iduronic acid) disaccharide repeats with epimerization and various sulfation modifications. HS is covalently attached to core proteins to form HS-proteoglycans.
Mark M, Fuster, Lianchun, Wang
openaire +2 more sources