Results 1 to 10 of about 98,029 (348)
Pathogens that infect mammalian cells via sulfonated glycosaminoglycans [PDF]
Frontiers in Cellular and Infection MicrobiologySulfonated glycosaminoglycans, such as heparan sulfate and dermatan sulfate, form major components of the cell surface and extracellular matrix, and display vital roles in mammalian physiology, including growth and development.
Jessica S. Morris, Paul A. Dawson
doaj +2 more sources
Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING [PDF]
Immunity, 2021 Yukun Guan, Zhengfan Jiang
exaly +2 more sources
Biomolecules, 2021 We analyzed children with urolithiasis with age- and gender-matched healthy children. Calcium (mmol/mmol creatinine) and the calcium/citrate ratio (mol/mmol) are the only variables that differentiate children before puberty from healthy children (ROC ...
Daniel Turudic +4 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2022 The objective of this study was to investigate the effects of exposure to endotoxin on the reproductive performance of humans and animals in pregnancy and delivery period.
Ming-ming Zhang +7 more
doaj +1 more source
Click-Chemistry-Assisted Alteration of Glycosaminoglycans for Biological Applications
SynOpen, 2023 This short review describes the assistance of click chemistry in the chemical modification of glycosaminoglycans. Through an alkyne-azide 1,3-dipolar cycloaddition reaction, the chemically and physiologically stable triazole unit connects ...
Smritilekha Bera, Dhananjoy Mondal
doaj +1 more source
High sensitivity analysis of nanogram quantities of glycosaminoglycans using ToF-SIMS
Communications Chemistry, 2021 Glycosaminoglycans are an important class of carbohydrates, but pose substantial analytical challenges. Here ToF-SIMS combined with multivariate analysis distinguishes six classes of glycosaminoglycans, including distinguishing heparin samples from ...
Andrew L. Hook +4 more
doaj +1 more source
Taiwan Journal of Ophthalmology, 2023 Mucopolysaccharidosis are group of inherited metabolic diseases caused by the absence or malfunctioning of lysosomal enzymes resulting in accumulation of glycosaminoglycans. Over time this accumulation damages cells, tissues, and organs.
Kusumitha Bhakthaganesh +5 more
doaj +1 more source
IR action spectroscopy of glycosaminoglycan oligosaccharides [PDF]
, 2020 Glycosaminoglycans (GAGs) are a physio- and pharmacologically highly relevant class of complex saccharides, possessing a linear sequence and strongly acidic character.
Freyse, Joanna +9 more
core +2 more sources
Modeling extracellular matrix through histo-molecular gradient in NSCLC for clinical decisions
Frontiers in Oncology, 2022 Lung cancer still represents a global health problem, being the main type of tumor responsible for cancer deaths. In this context, the tumor microenvironment, and the extracellular matrix (ECM) pose as extremely relevant.
Camila Machado Baldavira +10 more
doaj +1 more source
Evidence for the role of proteoglycans in cation-mediated gene transfer [PDF]
, 1996 We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated proteoglycans. Treatment of HeLa cells with sodium chlorate, a potent inhibitor of proteoglycan sulfation, reduced luciferase
Baldeschwieler, John D. +1 more
core +1 more source