Results 1 to 10 of about 100,368 (249)
Glycosaminoglycans and Proteoglycans
Pharmaceuticals, 2018 In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan,
Vitor H Pomin, Barbara Mulloy
exaly +4 more sources
Proteoglycans as Mediators of Cancer Tissue Mechanics [PDF]
Frontiers in Cell and Developmental Biology, 2020 Proteoglycans are a diverse group of molecules which are characterized by a central protein backbone that is decorated with a variety of linear sulfated glycosaminoglycan side chains.
Anna Barkovskaya +8 more
doaj +2 more sources
Proteoglycans and Neuronal Migration in the Cerebral Cortex During Development and Disease
Frontiers in Neuroscience, 2015 Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many proteins including growth factors, chemokines, axon guidance molecules,
Nobuaki Maeda
exaly +3 more sources
Pharmaceuticals, 2022 Cisplatin-based chemotherapy has been effectively used to treat oral cancer, but treatment often fails owing to the development of drug resistance. However, the important gene expression alterations associated with these resistances remain unclear.
Hyeong Sim Choi +2 more
doaj +1 more source
Diagnostics, 2022 The aim of this study was the preliminary assessment of a new cationic contrast agent, the CA4+, via the analysis of spatial distribution in cartilage of ex vivo bovine samples, at micrometer and millimeter scale.
Simone Fantoni +11 more
doaj +1 more source
Lumican in Carcinogenesis—Revisited
Biomolecules, 2021 Carcinogenesis is a multifactorial process with the input and interactions of environmental, genetic, and metabolic factors. During cancer development, a significant remodeling of the extracellular matrix (ECM) is evident.
Eirini-Maria Giatagana +4 more
doaj +1 more source
Alterations of Extracellular Matrix Components in the Course of Juvenile Idiopathic Arthritis
Metabolites, 2021 Juvenile idiopathic arthritis (JIA) is the most common group of chronic connective tissue diseases in children that is accompanied by joint structure and function disorders.
Magdalena Wojdas +2 more
doaj +1 more source
JOR Spine, 2022 Introduction Diabetes has long been implicated as a major risk factor for intervertebral disc (IVD) degeneration, interfering with molecular signaling and matrix biochemistry, which ultimately aggravates the progression of the disease.
Marianne Lintz +3 more
doaj +1 more source
Frontiers in Medicine, 2023 BackgroundCalcineurin inhibitors (CNIs) are associated with nephrotoxicity, endothelial cell dysfunction, and thrombotic microangiopathy (TMA). Evolving evidence suggests an important role for complement dysregulation in the pathogenesis of CNI-induced ...
Chia Wei Teoh +25 more
doaj +1 more source
Scoliotic disease: report to the teacher
Хирургия позвоночника, 2020 It is with gratitude that I dedicate my work to the teacher, Ya.L. Tsivyan, who not only provided a subject for research, but also, on his own example of a person devoted to his work, brought up a generation of scholars for whom life and science are ...
Alla M. Zaidman
doaj +1 more source