Results 11 to 20 of about 100,368 (249)

Heparan Sulfate Proteoglycans in Tauopathy [PDF]

, 2022
Tauopathies are a class of neurodegenerative diseases, including Alzheimer’s disease, and are characterized by intraneuronal tau inclusion in the brain and the patient’s cognitive decline with obscure pathogenesis.
Lauren Gandy, Fuming Zhang, Zhang, Fuming, Wang, Lianchun, Jian Liu, Wang, Chunyu, Blair, Laura J., Zhu, Yanan, Yanan Zhu, Chunyu Wang, Gandy, Lauren, Robert J. Linhardt, Linhardt, Robert J., Liu, Jian, Laura J. Blair, Lianchun Wang   +15 more
core   +1 more source

Molecular Properties of Water-Unextractable Proteoglycans from Hypsizygus marmoreus and Their in Vitro Immunomodulatory Activities

Molecules, 2011
Four proteoglycans were sequentially extracted from Hypsizygus marmoreus using 0.1 M NaOH (alkali-soluble proteoglycans [F1] and alkali-insoluble proteoglycans [F3]) and 0.1 M HCl (acid-soluble proteoglycans [F2] and acid-insoluble proteoglycans [F4 ...
Hee Mun Chae, Hong Hui Bao, Mehdi Tarbasa, Sang Guan You   +3 more
doaj   +1 more source

Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL

Journal of Lipid Research, 2003
Retention of LDL in the artery intima is mediated by extracellular matrix proteoglycans and plays an important role in the initiation of atherosclerosis.
C. Daniel Meyers, Lisa R. Tannock, Thomas N. Wight, Alan Chait   +3 more
doaj   +1 more source

Roles of Chondroitin Sulfate Proteoglycans as Regulators of Skeletal Development

Frontiers in Cell and Developmental Biology, 2022
The extracellular matrix (ECM) is critically important for most cellular processes including differentiation, morphogenesis, growth, survival and regeneration.
Nancy B. Schwartz, Nancy B. Schwartz, Miriam S. Domowicz   +2 more
doaj   +1 more source

Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges [PDF]

, 2000
Jarchow J, Fritz J, Anselmetti D, et al. Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges. Journal of structural biology.
Fritz, Jürgen, Gerosa, Daniela, Burger, Max M., Calabro, Anthony, Fernandez-Busquets, Xavier, Hascall, Vincent C., Jarchow, Janina, Anselmetti, Dario ; https://orcid.org/, Fernàndez-Busquets X, Jarchow J, Gerosa D, Burger MM, Calabro A, Fritz J, Hascall VC, Anselmetti D   +15 more
core   +1 more source

The effect of proteoglycans inhibited by RNA interference on metastatic characters of human salivary adenoid cystic carcinoma

BMC Cancer, 2009
Background Salivary adenoid cystic carcinoma (SACC) is one of the most common malignancies of salivary gland. Recurrence or/and early metastasis is its biological properties.
Li Hexiang, Wang Xu, Dong Fusheng, Wang Jie, Shi Hong, Hou Yali   +5 more
doaj   +1 more source

Proteoglycan desulfation: a critical step in oncogenesis?

Frontiers in Bioscience-Landmark, 2020
Proteoglycans are essential constituents of tissue- and organ microenvironments, modulating both the structural scaffolds that surround cells as well as signaling cues that determine cellular phenotype.
Vishal Singh, Ramray Bhat
doaj   +1 more source

Regulation of human neural stem cell fate determination by proteoglycans [PDF]

, 2017
This thesis investigated how human neural stem cells are regulated, focusing specifically on heparan sulfate proteoglycans, the key proteins of the extracellular space.
Oikari, Lotta Emilia
core   +1 more source

Effect of glycosaminoglycans on the structure and composition of articular cartilage and bone of broilers

Poultry Science, 2023
: This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet of broilers on the expression of matrix metallopeptidase 9 (MMP-9) and metallopeptidase inhibitor 2 (TIMP-2) genes, the ...
Julyana M.S. Martins, Lindolfo D. dos Santos Neto, Sarah Sgavioli, Itallo C.S. Araújo, Angela A.S. Reis, Rodrigo S. Santos, Eugênio G. de Araújo, Nadja S.M. Leandro, Marcos B. Café   +8 more
doaj   +1 more source

Proteoglycans in the nervous system [PDF]

, 1993
Proteoglycans are ubiquitous cell-surface and secreted glycoproteins that are involved in diverse cellular behaviors. The identities of several nervous system proteoglycans, including many of the major species in the mammalian brain, have recently come ...
Arthur D. Lander, Lander, Arthur D
core   +1 more source