Results 11 to 20 of about 17,769 (248)

Hair follicle proteoglycans

open access: yesJournal of Investigative Dermatology, 1993
Proteoglycans are polymorphic macromolecules present in all mammalian tissues, including the skin and its appendages. They consist of a core protein to which one or more glycosaminoglycan chains are covalently attached. Broadly, they can be divided into classes based on location and core protein structure.
Couchman, J R
core   +4 more sources

Editorial: Proteoglycans in the Tumor Microenvironment [PDF]

open access: yesFrontiers in Oncology, 2022
Proteoglycans (PGs) are a family of heavily glycosylated proteins consisting of a core protein covalently attached to glycosaminoglycans (GAGs) and present in diverse environments, such as cell membrane surface, extracellular matrix, and intracellular ...
Jlenia Brunetti   +2 more
doaj   +2 more sources

The loss of glycocalyx integrity impairs complement factor H binding and contributes to cyclosporine-induced endothelial cell injury

open access: yesFrontiers in Medicine, 2023
BackgroundCalcineurin inhibitors (CNIs) are associated with nephrotoxicity, endothelial cell dysfunction, and thrombotic microangiopathy (TMA). Evolving evidence suggests an important role for complement dysregulation in the pathogenesis of CNI-induced ...
Chia Wei Teoh   +25 more
doaj   +1 more source

Scoliotic disease: report to the teacher

open access: yesХирургия позвоночника, 2020
It is with gratitude that I dedicate my work to the teacher, Ya.L. Tsivyan, who not only provided a subject for research, but also, on his own example of a person devoted to his work, brought up a generation of scholars for whom life and science are ...
Alla M. Zaidman
doaj   +1 more source

Proteoglycans and Osteolysis [PDF]

open access: yes, 2011
Osteolysis is a complex mechanism resulting from an exacerbated activity of osteoclasts associated or not with a dysregulation of osteoblast metabolism leading to bone loss. This bone defect is not compensated by bone apposition or by apposition of bone matrix with poor mechanical quality.
Baud'Huin, Marc   +6 more
openaire   +4 more sources

Molecular Properties of Water-Unextractable Proteoglycans from Hypsizygus marmoreus and Their in Vitro Immunomodulatory Activities

open access: yesMolecules, 2011
Four proteoglycans were sequentially extracted from Hypsizygus marmoreus using 0.1 M NaOH (alkali-soluble proteoglycans [F1] and alkali-insoluble proteoglycans [F3]) and 0.1 M HCl (acid-soluble proteoglycans [F2] and acid-insoluble proteoglycans [F4 ...
Hee Mun Chae   +3 more
doaj   +1 more source

Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges [PDF]

open access: yes, 2000
Jarchow J, Fritz J, Anselmetti D, et al. Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges. Journal of structural biology.
Fritz, Jürgen   +7 more
core   +1 more source

Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL

open access: yesJournal of Lipid Research, 2003
Retention of LDL in the artery intima is mediated by extracellular matrix proteoglycans and plays an important role in the initiation of atherosclerosis.
C. Daniel Meyers   +3 more
doaj   +1 more source

Roles of Chondroitin Sulfate Proteoglycans as Regulators of Skeletal Development

open access: yesFrontiers in Cell and Developmental Biology, 2022
The extracellular matrix (ECM) is critically important for most cellular processes including differentiation, morphogenesis, growth, survival and regeneration.
Nancy B. Schwartz   +2 more
doaj   +1 more source

Proteoglycans and neuronal migration in the cerebral cortex during development and disease

open access: yesFrontiers in Neuroscience, 2015
Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many proteins including growth factors, chemokines, axon guidance molecules,
Nobuaki eMaeda
doaj   +1 more source

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