Results 21 to 30 of about 17,769 (248)

The podocyte and the proteoglycan [PDF]

open access: yesAmerican Journal of Physiology-Renal Physiology, 2016
proteoglycans (PGs) consist of a core protein and linear sugar side chains [glycosaminoglycans (GAGs)] attached to the core protein, e.g., agrin, perlecan, glypican, and syndecan. GAGs comprise repeating duplex sugar units made of an aminosugar (e.g., N -acetylglucosamine or N -acetylgalactosamine)
openaire   +2 more sources

The effect of proteoglycans inhibited by RNA interference on metastatic characters of human salivary adenoid cystic carcinoma

open access: yesBMC Cancer, 2009
Background Salivary adenoid cystic carcinoma (SACC) is one of the most common malignancies of salivary gland. Recurrence or/and early metastasis is its biological properties.
Li Hexiang   +5 more
doaj   +1 more source

Proteoglycan desulfation: a critical step in oncogenesis?

open access: yesFrontiers in Bioscience-Landmark, 2020
Proteoglycans are essential constituents of tissue- and organ microenvironments, modulating both the structural scaffolds that surround cells as well as signaling cues that determine cellular phenotype.
Vishal Singh, Ramray Bhat
doaj   +1 more source

Regulation of human neural stem cell fate determination by proteoglycans [PDF]

open access: yes, 2017
This thesis investigated how human neural stem cells are regulated, focusing specifically on heparan sulfate proteoglycans, the key proteins of the extracellular space.
Oikari, Lotta Emilia
core   +1 more source

Effect of glycosaminoglycans on the structure and composition of articular cartilage and bone of broilers

open access: yesPoultry Science, 2023
: This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet of broilers on the expression of matrix metallopeptidase 9 (MMP-9) and metallopeptidase inhibitor 2 (TIMP-2) genes, the ...
Julyana M.S. Martins   +8 more
doaj   +1 more source

Carbohydrate–carbohydrate interaction provides adhesion force and specificity for cellular recognition [PDF]

open access: yes, 2004
© 2004 Bucior et al. This article is distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. The definitive version was published in Journal of Cell Biology 165 (2004): 529-537, doi:10.1083/jcb ...
Bucior, Iwona   +11 more
core   +1 more source

Nondestructive fluorescence lifetime imaging and time-resolved fluorescence spectroscopy detect cartilage matrix depletion and correlate with mechanical properties [PDF]

open access: yesEuropean Cells & Materials, 2018
Tissue engineers utilize a battery of expensive, time-consuming and destructive techniques to assess the composition and function of engineered tissues.
AK Haudenschild   +6 more
doaj   +1 more source

Proteoglycans and catabolic products of proteoglycans present in ligament [PDF]

open access: yesBiochemical Journal, 2005
The aim of the present study was to characterize the proteoglycans and catabolic products of proteoglycans present in the tensile region of ligament and explant cultures of this tissue, and to compare these with those observed in the tensile region of tendon. Approx.
Ilic, Mirna Z.   +4 more
openaire   +2 more sources

Cytokines and proteoglycans [PDF]

open access: yesExperientia, 1993
Cytokines play an important regulatory role in the metabolism of proteoglycans. Proteoglycans are found in plasma membranes, but predominantly in the extra-cellular matrix. In the latter they are quantitatively and qualitatively essential components. Especially in a tissue like cartilage without any blood vessels, the cells are dependent on cytokines ...
openaire   +2 more sources

Extracellular proteoglycans: A multiscale computational study [PDF]

open access: yes, 2023
The extracellular matrix (ECM) plays an important role in cell migration and proliferation, and hence in the progression of malignant tumors. Healthy brain is one of the softest tissues, but in cancer, the stiffness of the brain ECM can increase by one ...
Van, Erik   +4 more
core   +1 more source

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