Production and HPLC-Based Disaccharide Analysis of Xyloside-Primed Glycosaminoglycans
, 2021 Although glycosaminoglycans (GAGs) are known to be involved in a variety of physiological and pathological processes, knowledge about their expression by cells or tissues, the GAGome, is limited.
Persson, Andrea +11 more
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Chlorination and oxidation of heparin and hyaluronan by hypochlorous acid and hypochlorite anions: effect of sulfate groups on reaction pathways and kinetics. [PDF]
, 2013 Hypochlorous acid (HOCl), produced in inflammatory conditions by the enzyme myeloperoxidase, and its anion hypochlorite (OCl(-)) exist in vivo at almost equal concentrations.
Parsons, BJ +4 more
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Glycosaminoglycans in Tissue Engineering: A Review [PDF]
, 2020 Glycosaminoglycans are native components of the extracellular matrix that drive cell behavior and control the microenvironment surrounding cells, making them promising therapeutic targets for a myriad of diseases.
Sodhi, Harkanwalpreet +3 more
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Horizontal gene transfer contributed to the evolution of extracellular surface structures [PDF]
, 2012 The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium.
Böttger, Angelika +13 more
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ROLE OF GLYCOSAMINOGLYCANS IN DIABETIC NEPHROPATHY [PDF]
, 1992 A number of abnormalities of glycosaminoglycan metabolism have been reported in diabetes mellitus. These include anomalous synthesis, catabolism and sulphation.
Baggio B. +3 more
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Reaction of superoxide radicals with glycosaminoglycan chloramides: a kinetic study.
, 2013 Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, perhaps through the binding of myeloperoxidase directly to the glycosaminoglycans.
Parsons, BJ +7 more
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Applications of Glycosaminoglycans in the Medical, Veterinary, Pharmaceutical, and Cosmetic Fields
, 2017 Glycosaminoglycans (GAGs) are complex polysaccharides ubiquitously present in the extracellular matrix of mammalian tissues, where they constitute the gelatinous material responsible of maintaining the cells together, in an intimate association with a ...
Kovensky, Jose Eduardo +5 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Fractionation Of Glycosaminoglycans From Psoriatic Skin
, 1970 Skin samples from 3 patients with active psoriasis, one with seborrheic dermatitis and 9 normal controls were subjected to qualitative and quantitative analysis of glycosaminoglycans.
Fleischmajer, Raul, Blumenkrantz, Nelly
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Click-Chemistry-Assisted Alteration of Glycosaminoglycans for Biological Applications
, 2023 This short review describes the assistance of click chemistry in the chemical modification of glycosaminoglycans. Through an alkyne-azide 1,3-dipolar cycloaddition reaction, the chemically and physiologically stable triazole unit connects ...
Dhananjoy Mondal, Smritilekha Bera
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