Results 21 to 30 of about 61,693 (251)

Heparan Sulfate, Mucopolysaccharidosis IIIB and Sulfur Metabolism Disorders

Antioxidants, 2022
Mucopolysaccharidosis, type IIIB (MPS IIIB) is a rare disease caused by mutations in the N-alpha-acetylglucosaminidase (NAGLU) gene resulting in decreased or absent enzyme activity.
Marta Kaczor-Kamińska, Kamil Kamiński, Maria Wróbel   +2 more
doaj   +1 more source

Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle

Clinics, 2010
OBJECTIVE: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle. DESIGN: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI ...
Jairo Jose Matozinho Cubas, Ricardo Santos Simões, Ricardo Martins Oliveira-Filho, Manuel Jesus Simões, Edmund C Baracat, José Maria Soares-Jr   +5 more
doaj   +1 more source

Diagnosis of Mucopolysaccharidoses and Mucolipidosis by Assaying Multiplex Enzymes and Glycosaminoglycans

Diagnostics, 2021
Mucopolysaccharidoses (MPS) and mucolipidosis (ML II/III) are a group of lysosomal storage disorders (LSDs) that occur due to a dysfunction of the lysosomal hydrolases responsible for the catabolism of glycosaminoglycans (GAGs).
Nivethitha Arunkumar, Dung Chi Vu, Shaukat Khan, Hironori Kobayashi, Thi Bich Ngoc Can, Tsubasa Oguni, Jun Watanabe, Misa Tanaka, Seiji Yamaguchi, Takeshi Taketani, Yasuhiko Ago, Hidenori Ohnishi, Sampurna Saikia, José V. Álvarez, Shunji Tomatsu   +14 more
doaj   +1 more source

Melittin-Related Peptides Interfere with Sandfly Fever Naples Virus Infection by Interacting with Heparan Sulphate

Microorganisms, 2023
Emerging viruses pose an important global public health challenge, and early action is needed to control their spread. The Bunyaviridae family contains a great number of arboviruses which are potentially pathogenic for humans.
Annalisa Chianese, Carla Zannella, Francesca Palma, Laura Di Clemente, Alessandra Monti, Nunzianna Doti, Anna De Filippis, Massimiliano Galdiero   +7 more
doaj   +1 more source

Production and HPLC-Based Disaccharide Analysis of Xyloside-Primed Glycosaminoglycans

, 2021
Although glycosaminoglycans (GAGs) are known to be involved in a variety of physiological and pathological processes, knowledge about their expression by cells or tissues, the GAGome, is limited.
Persson, Andrea, Katrin Mani, Persson, Andrea,, Ellervik, U., Mani, Katrin, Emil Tykesson, Ellervik, Ulf, Andrea Persson, Ulf Ellervik, Tykesson, Emil, Tykesson, E., Mani, K., Ellervik, Ulf,, Mani, Katrin,, Tykesson, Emil,, Lund University.   +15 more
core   +1 more source

ROLE OF GLYCOSAMINOGLYCANS IN DIABETIC NEPHROPATHY [PDF]

, 1992
A number of abnormalities of glycosaminoglycan metabolism have been reported in diabetes mellitus. These include anomalous synthesis, catabolism and sulphation.
Baggio B., Gambaro G., GAMBARO G, BAGGIO, BRUNO   +3 more
core   +1 more source

THE EXCHANGE OF CONNECTIVE TISSUE BIOPOLYMERS IN THE LIVER OF ALLOXAN DIABETIC RATS

Бюллетень сибирской медицины, 2013
Aim. Study of the exchange of liver and blood plasma biopolymers of alloxan diabetic rats.Materials and Methods. Diabetes mellitus was modeled in rats by single subcutaneous injection of alloxan tetrahydrate (170 mg per100 gbody weight).
S. V. Lomaeva, I. F. Gette, T. S. Bulavintseva, S. E. Perevedentseva, I. G. Danilova   +4 more
doaj   +1 more source

Natural Presentation of Glycosaminoglycans in Synthetic Matrices for 3D Angiogenesis Models

Frontiers in Cell and Developmental Biology, 2021
Glycosaminoglycans (GAGs) are long, linear polysaccharides that occur in the extracellular matrix of higher organisms and are either covalently attached to protein cores, as proteoglycans or in free form.
Cornelia Zapp, Cornelia Zapp, Patricia Mundinger, Patricia Mundinger, Heike Boehm, Heike Boehm   +5 more
doaj   +1 more source

Functionality of surface-coupled oxidised glycosaminoglycans towards fibroblast adhesion [PDF]

, 2015
Glycosaminoglycans are able to bind many growth factors and adhesive proteins, which affect cell activities such as adhesion, migration, growth and differentiation.
Yang, Y., Mäder, Karsten, Groth, T., Pashkuleva, I., Köwitsch, A., Ma, Ning, Reis, R. L.   +6 more
core   +1 more source

Sulfated Glycoaminoglycans and Proteoglycan Syndecan-4 Are Involved in Membrane Fixation of LL-37 and Its Pro-Migratory Effect in Breast Cancer Cells

Biomolecules, 2019
Initially characterized by its antimicrobial activities, LL-37 has also been shown to significantly contribute to tumor development. On breast cancer cell lines, LL-37 increases intracellular calcium via the TRPV2 channel and their migration via the ...
Chahrazed Habes, Günther Weber, Caroline Goupille   +2 more
doaj   +1 more source