Results 21 to 30 of about 60,454 (182)
Glycosaminoglycans (GAGs) are important constituents of human glycome. They are negatively charged unbranched polysaccharides that are usually covalently attached to proteins, forming glycan-protein conjugates, called proteoglycans. Glycosaminoglycans play critical roles in numerous biological processes throughout individual development and are also ...
Yuefan, Song +2 more
+7 more sources
Glycosaminoglycans, protein aggregation and neurodegeneration.
International audienceA number of neurodegenerative diseases, as Parkinson, prion, and Alzheimer's diseases, has been directly associated with altered conformations of certain peptides or proteins that assemble to form highly organized aggregates, also ...
Papy-Garcia, Dulce +6 more
core +8 more sources
We analyzed children with urolithiasis with age- and gender-matched healthy children. Calcium (mmol/mmol creatinine) and the calcium/citrate ratio (mol/mmol) are the only variables that differentiate children before puberty from healthy children (ROC ...
Daniel Turudic +4 more
doaj +1 more source
The objective of this study was to investigate the effects of exposure to endotoxin on the reproductive performance of humans and animals in pregnancy and delivery period.
Ming-ming Zhang +7 more
doaj +1 more source
High sensitivity analysis of nanogram quantities of glycosaminoglycans using ToF-SIMS
Glycosaminoglycans are an important class of carbohydrates, but pose substantial analytical challenges. Here ToF-SIMS combined with multivariate analysis distinguishes six classes of glycosaminoglycans, including distinguishing heparin samples from ...
Andrew L. Hook +4 more
doaj +1 more source
Glycosaminoglycans in biomedicine [PDF]
AbstractGlycosaminoglycans (GAGs) compose one of four classes of mammalian biopolymers, and are arguably the most complex. The research areas of glycobiology, glycopolymers, and the use of GAGs within tissue engineering and regenerative medicine have grown exponentially during the past decade.
Rebecca A, Scott, Alyssa, Panitch
openaire +2 more sources
Production and HPLC-Based Disaccharide Analysis of Xyloside-Primed Glycosaminoglycans
Although glycosaminoglycans (GAGs) are known to be involved in a variety of physiological and pathological processes, knowledge about their expression by cells or tissues, the GAGome, is limited.
Persson, Andrea +11 more
core +1 more source
Mucopolysaccharidosis are group of inherited metabolic diseases caused by the absence or malfunctioning of lysosomal enzymes resulting in accumulation of glycosaminoglycans. Over time this accumulation damages cells, tissues, and organs.
Kusumitha Bhakthaganesh +5 more
doaj +1 more source
Glycosaminoglycans and infection [PDF]
Glycosaminoglycans (GAGs) are complex linear polysaccharides expressed in intracellular compartments, at the cell surface, and in the extracellular environment where they interact with various molecules to regulate many cellular processes implicated in health and disease. Subversion of GAGs is a pathogenic strategy shared by a wide variety of microbial
Rafael S, Aquino, Pyong Woo, Park
openaire +2 more sources
Glycosaminoglycans and the peritoneaum [PDF]
SUMMARY: The introduction of peritoneal dialysis (PD) over two decades ago has allowed us to manipulate the peritoneal membrane to perform as a continuous dialysing organ. to maximize the efficacy of solute transport and waste removal, conventional PD fluids require unphysiological concentrations of glucose to provide the osmotic drive, lactate to ...
Yung, S, Chan, TM
openaire +3 more sources

