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Cell surface heparan sulfate proteoglycans and lipoprotein metabolism
Cellular and Molecular Life Sciences, 1999Markku Salmivirta
exaly
Heparan Sulfate Proteoglycans in Tauopathy [PDF]
Tauopathies are a class of neurodegenerative diseases, including Alzheimer’s disease, and are characterized by intraneuronal tau inclusion in the brain and the patient’s cognitive decline with obscure pathogenesis.
Chunyu Wang +2 more
exaly +8 more sources
Heparan Sulfate Proteoglycans in Human Colorectal Cancer [PDF]
Colorectal cancer is the third most common cancer worldwide, accounting for more than 610,000 mortalities every year. Prognosis of patients is highly dependent on the disease stage at diagnosis.
Carolina Meloni Vicente +7 more
doaj +3 more sources
Heparan sulfate proteoglycans and cancer [PDF]
Heparan sulfate proteoglycans (HSPGs) are widely distributed in mammalian tissues and involved in a number of processes related to malignancy. They are composed of a core protein to which chains of the glycosaminoglycan, heparan sulfate (HS), are attached.
Blackhall, F. H.; id_orcid 0000-0001-8716-3395 +3 more
openaire +3 more sources
A Genome-Wide CRISPR/Cas9-Based Screen Identifies Heparan Sulfate Proteoglycans as Ligands of Killer-Cell Immunoglobulin-Like Receptors [PDF]
While human leukocyte antigen (HLA) and HLA-like proteins comprise an overwhelming majority of known ligands for NK-cell receptors, the interactions of NK-cell receptors with non-conventional ligands, particularly carbohydrate antigens, is less well ...
Klara Klein +16 more
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Heparan sulfate proteoglycans are highly glycosylated proteins in which heparan sulfate, a glycosaminoglycan sugar chain, is an acidic sugar chain consisting of a repeating disaccharide structure of glucuronic acid and N-acetylglucosamine is locally ...
Yasunari Matsuzaka, Ryu Yashiro
doaj +2 more sources
Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression [PDF]
Heparan sulfate (HS) are complex unbranched carbohydrate chains that are heavily modified by sulfate and exist either conjugated to proteins or as free, unconjugated chains. Proteins with covalently bound Heparan sulfate chains are termed Heparan Sulfate
Arvindhan Nagarajan +3 more
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White adipose tissues are major endocrine organs that release factors, termed adipokines, which affect other major organ systems. The development and functions of adipose tissues depend largely upon the glycosaminoglycan heparan sulfate.
J. Michael Sorrell, Arnold I. Caplan
doaj +2 more sources
Heparan Sulfate Proteoglycans: Key Mediators of Stem Cell Function [PDF]
Heparan sulfate proteoglycans (HSPGs) are an evolutionarily ancient subclass of glycoproteins with exquisite structural complexity. They are ubiquitously expressed across tissues and have been found to exert a multitude of effects on cell behavior and ...
Maanasa Ravikumar +6 more
doaj +2 more sources

