Results 41 to 50 of about 267,445 (243)
Poultry Science, 2020 : Adult myoblasts, satellite cells, will proliferate, and differentiate into myotubes in vitro. However, changes in environmental and nutritional conditions will result in the satellite cells differentiating into adipocyte-like cells synthesizing lipids.
Sandra G. Velleman, Cynthia S. Coy
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Inhibition of Plasmodium falciparum growth in vitro and adhesion to chondroitin-4-sulfate by the heparan sulfate mimetic PI-88 and other sulfated oligosaccharides [PDF]
, 2006 A panel of sulfated oligosaccharides was tested for antimalarial activity and inhibition of adhesion to the placental malaria receptor chondroitin-4-sulfate (CSA).
Andrews, K.T. +15 more
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Nature Communications, 2021 Lysosomal storage disorders, characterized by altered metabolism of heparan sulfate, cause autistic symptoms followed by dementia in children. Here, the authors show that embryonic dopaminergic neurodevelopmental defects due to altered function of ...
Maria De Risi +19 more
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Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress
Viruses, 2021 Heparan sulfate (HS) and heparan sulfate proteoglycans (HSPGs) are considered important for the entry of many different viruses. Previously, we demonstrated that heparanase (HPSE), the host enzyme responsible for cleaving HS chains, is upregulated by ...
Ghadah A. Karasneh +4 more
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Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling [PDF]
Brazilian Journal of Medical and Biological Research, 2006 The syndecans, heparan sulfate proteoglycans, are abundant molecules associated with the cell surface and extracellular matrix and consist of a protein core to which heparan sulfate chains are covalently attached. Each of the syndecan core proteins has a
C.C. Lopes, C.P. Dietrich, H.B. Nader
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Heparan Sulfate Biosynthesis in Zebrafish [PDF]
Journal of Histochemistry & Cytochemistry, 2020 The biosynthesis of heparan sulfate (HS) proteoglycans occurs in the Golgi compartment of cells and will determine the sulfation pattern of HS chains, which in turn will have a large impact on the biological activity of the proteoglycans. Earlier studies in mice have demonstrated the importance of HS for embryonic development.
Filipek-Górniok B +3 more
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Targeting heparin and heparan sulfate protein interactions [PDF]
, 2017 Heparan sulfate is ubiquitously expressed on the cell surface and in the extracellular matrix of all animal cells. These negatively-charged carbohydrate chains play essential roles in many important cellular functions by interacting with various heparan ...
Jeffrey D. Esko +5 more
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Heparan Sulfate-Dependent Enhancement of Henipavirus Infection
mBio, 2015 Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus. They infect humans as well as numerous mammalian species.
Cyrille Mathieu +9 more
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Scientific Reports, 2022 Recent reports demonstrate that SARS-CoV-2 utilizes cell surface heparan sulfate as an attachment factor to facilitate the initial interaction with host cells.
Yulia Kiyan +6 more
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Heparan Sulfate Biosynthesis [PDF]
Journal of Histochemistry & Cytochemistry, 2012 Nearly all vertebrate cells have been shown to express heparan sulfate proteoglycans (HSPGs) at the cell surface. The HSPGs bind to many secreted signaling proteins, including numerous growth factors, cytokines, and morphogens, to affect their tissue distribution and signaling.
Kreuger J, Kjellén L
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