Results 61 to 70 of about 41,050 (163)

Coxsackievirus A16 utilizes cell surface heparan sulfate glycosaminoglycans as its attachment receptor

Emerging Microbes and Infections, 2017
Coxsackievirus A16 (CVA16) is one of the major pathogens responsible for hand, foot and mouth disease, which affects more than two million children in the Asian-Pacific region annually.
Xueyang Zhang, Jinping Shi, Xiaohua Ye, Zhiqiang Ku, Chao Zhang, Qingwei Liu, Zhong Huang   +6 more
doaj   +1 more source

Fibroblast EXT1-levels influence tumor cell proliferation and migration in composite spheroids.

PLoS ONE, 2012
BackgroundStromal fibroblasts are important determinants of tumor cell behavior. They act to condition the tumor microenvironment, influence tumor growth, support tumor angiogenesis and affect tumor metastasis. Heparan sulfate proteoglycans, present both
Cecilia Österholm, Ning Lu, Åsa Lidén, Tine V Karlsen, Donald Gullberg, Rolf K Reed, Marion Kusche-Gullberg   +6 more
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Introduction to the Molecules Special Edition Entitled ‘Heparan Sulfate and Heparin: Challenges and Controversies’: Some Outstanding Questions in Heparan Sulfate and Heparin Research

Molecules, 2019
The scope of this article is to provide a brief general introduction to heparan sulfate (HS) and heparin, and attempt to identify some of the central challenges regarding research into the chemistry and biology of glycosaminoglycans (GAGs), some of which
Edwin A Yates, John T Gallagher, Marco Guerrini   +2 more
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The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition

International Journal of Biological Sciences, 2011
Six genes involved in the heparan sulfate and heparin metabolism pathway, DSEL (dermatan sulfate epimerase-like), EXTL1 (exostoses (multiple)-like 1), HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), HS6ST3 (heparan sulfate 6-O-sulfotransferase 3), NDST3
Zhihua Jiang, Jennifer J. Michal, Xiao-Lin Wu, Zengxiang Pan, Michael D. MacNeil
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Comparison of the Effects of Sevoflurane and Desflurane on Endothelial Glycocalyx in Patients Undergoing Laparoscopic Hysterectomy: A Randomized, Double-Blind Trial

Turkish Journal of Anaesthesiology and Reanimation
Objective: Various enzymes, reactive oxygen species, inflammatory conditions, and major surgeries cause endothelial glycocalyx breakdown. Inhalation of anaesthetic agents may have protective effects on the endothelium.
Kemal Tolga Saraçoğlu, Tahsin Şimşek, Hande Gürbüz, Fatih Doğu Geyik, Ebru Kale, Kürşad Nuri Baydili, Raghad Giuma M. Kordi, Ahmet Kale, Ayten Saraçoğlu   +8 more
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Heparan sulfate: Antithrombotic or not? [PDF]

Journal of Clinical Investigation, 2003
openaire   +2 more sources

The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer

Breast Cancer Research
Background Breast cancer, one of the most common forms of cancer, is associated with the highest cancer-related mortality among women worldwide. In comparison to other types of breast cancer, patients diagnosed with the triple-negative breast cancer ...
Jasmine M. Manouchehri, Jharna Datta, Lynn M. Marcho, Jesse J. Reardon, Daniel Stover, Robert Wesolowski, Uma Borate, Ting-Yuan David Cheng, Patrick M. Schnell, Bhuvaneswari Ramaswamy, Gina M. Sizemore, Mark P. Rubinstein, Mathew A. Cherian   +12 more
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Regulated Diversity of Heparan Sulfate [PDF]

Journal of Biological Chemistry, 1998
U, Lindahl, M, Kusche-Gullberg, L, Kjellén   +2 more
openaire   +2 more sources

Molecular diversity of heparan sulfate [PDF]

Journal of Clinical Investigation, 2001
J D, Esko, U, Lindahl
openaire   +2 more sources

Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors

Brazilian Journal of Medical and Biological Research, 2003
Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be ...
Gozzo A.J., Nunes V.A., Nader H.B., Dietrich C.P., Carmona A.K., Sampaio M.U., Sampaio C.A.M., Araújo M.S.   +7 more
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