Results 71 to 80 of about 76,553 (211)

Syndecan-4 Modulates Cell Polarity and Migration by Influencing Centrosome Positioning and Intracellular Calcium Distribution

Frontiers in Cell and Developmental Biology, 2020
Efficient cell migration requires cellular polarization, which is characterized by the formation of leading and trailing edges, appropriate positioning of the nucleus and reorientation of the Golgi apparatus and centrosomes toward the leading edge ...
Daniel Becsky, Kitti Szabo, Szuzina Gyulai-Nagy, Tamas Gajdos, Zsuzsa Bartos, Arpad Balind, Laszlo Dux, Peter Horvath, Miklos Erdelyi, Laszlo Homolya, Aniko Keller-Pinter   +10 more
doaj   +1 more source

Decorin proteoglycan inhibitor of fibrinogen blood clotting [PDF]

, 2004
The present invention provides compositions and methods of inhibiting fibrin(ogen) clot formation by utilizing decorin proteoglycan as an anticoagulating and antithrombotic agent.
H??k, Magnus, Dugan, Tracey A., H����k, Magnus, Höök, Magnus   +3 more
core  

Expression of transcription factors KLF2 and KLF4 is induced by the mammalian Golgi stress response

Cell Structure and Function
The Golgi stress response is a homeostatic mechanism that augments Golgi function when Golgi function becomes insufficient (Golgi stress). Glycosylation of the core proteins of proteoglycans is one of the important functions of the Golgi.
Kanae Sasaki, Reishi Tanaka, Iona Miyake, Miyu Sakamoto, Ryuya Tanaka, Azusa Tanaka, Misaki Terami, Ryota Komori, Mai Taniguchi, Sadao Wakabayashi, Hajime Tajima Sakurai, Hiderou Yoshida   +11 more
doaj   +1 more source

Structure-Activity Relationships of Bioengineered Heparin/Heparan Sulfates Produced in Different Bioreactors

Molecules, 2017
Heparin and heparan sulfate are structurally-related carbohydrates with therapeutic applications in anticoagulation, drug delivery, and regenerative medicine.
Ha Na Kim, John M. Whitelock, Megan S. Lord   +2 more
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Glucocorticoid regulation of proteoglycan synthesis in mesangial cells [PDF]

, 2002
Glucocorticoid regulation of proteoglycan synthesis in mesangial cells.BackgroundProteoglycans are integral components of the mesangial matrix and glomerular permeability barrier.
Mifune, Mizuo, Nakaya, Hideaki, Kuroda, Mari, Shimizu-Hirota, Ryoko, Hayashi, Matsuhiko, Saruta, Takao, Sasamura, Hiroyuki, Kobayashi, Emi   +7 more
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Structural Variation of Chondroitin Sulfate Chains Contributes to the Molecular Heterogeneity of Perineuronal Nets

Frontiers in Integrative Neuroscience, 2018
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain ...
Shinji Miyata, Satomi Nadanaka, Michihiro Igarashi, Hiroshi Kitagawa   +3 more
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Cholinergic vesicle specific proteoglycan: Stability in isolated vesicles and in synaptosomes during induced transmitter release. [PDF]

, 1988
Exposure of synaptosomes isolated from the electric organ of Torpedo marmorata to conditions that promote the release of acetylcholine does not cause the co-release of a vesicle specific proteoglycan.
Kuhn, D., Volknandt, W., Stadler, H., Zimmermann, H.   +3 more
core   +1 more source

Degradation of Cartilage Proteoglycan by Human Leukocyte Granule Neutral Proteases-A Model of Joint Injury II. DEGRADATION OF ISOLATED BOVINE NASAL CARTILAGE PROTEOGLYCAN [PDF]

, 2020
A B S T R A C T Extracts of human peripheral blood polymorphonuclear leukocyte granules, and two purified proteases derived from such extracts, an elastase and a chymotrypsin-like enzyme, degrade isolated bovine nasal cartilage proteoglycan at neutral pH.

core  

Immunopurification and characterization of a neuronal heparan sulfate proteoglycan [PDF]

, 1985
We have identified a unique heparan sulfate (HeS) proteoglycan synthesized by the neuronal-like cell line PC12. The proteoglycan, purified with monoclonal antibodies from medium conditioned by PC12 cells, has an apparent molecular weight of 350,000, and ...
RJ Greenspan, Greenspan, RJ, WD Matthew, AD Lander, Reichardt, LF, Matthew, WD, LF Reichardt, Lander, AD   +7 more
core   +1 more source

Quantitative magnetic resonance imaging of articular cartilage in osteoarthritis [PDF]

European Cells & Materials, 2007
Magnetic resonance imaging of articular cartilage has recently been recognized as a tool for the characterization of cartilage morphology, biochemistry and function.
G Blumenkrantz, S Majumdar
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