Results 81 to 90 of about 117,764 (297)

The mechanical and material properties of elderly human articular cartilage subject to impact and slow loading [PDF]

, 2013
Copyright © 2013 IPEM. Published by Elsevier Ltd.
Aspden, Aspden, Aspden, Aspden, Athanasiou, Athanasiou, Barker, Brown, Burgin, Burgin, Demarteau, Eberhardt, Edelsten, Finlay, Finlay, Froimson, Hukins, Ignat’eva, Jeffrey, Jeffrey, Kempson, Kempson, Kim, L. Edelsten, L.V. Burgin, Lewis, Little, Maroudas, Martin, Milentijevic, Milentijevic, Natoli, Nissi, Odgaard, Oloyede, Pedersen, Plumb, Pytel, R.M. Aspden, Radin, Radin, Shepherd, Shepherd, Stone, Stronge, Thomas, Treppo, Venn, Verteramo, Woessner, Zhu   +50 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Structure-Activity Relationships of Bioengineered Heparin/Heparan Sulfates Produced in Different Bioreactors

Molecules, 2017
Heparin and heparan sulfate are structurally-related carbohydrates with therapeutic applications in anticoagulation, drug delivery, and regenerative medicine.
Ha Na Kim, John M. Whitelock, Megan S. Lord   +2 more
doaj   +1 more source

Mast Cell Proteoglycans [PDF]

Journal of Histochemistry & Cytochemistry, 2012
Mast cells are versatile effector cells of the immune system, contributing to both innate and adaptive immunity toward pathogens but also having profound detrimental activities in the context of inflammatory disease. A hallmark morphological feature of mast cells is their large content of cytoplasmic secretory granules, filled with numerous secretory ...
Elin, Rönnberg, Fabio R, Melo, Gunnar, Pejler   +2 more
openaire   +2 more sources

Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. [PDF]

, 2018
The extracellular matrix is a master regulator of tissue homeostasis in health and disease. Here we examined how the small, leucine-rich, extracellular matrix proteoglycan decorin regulates cardiomyocyte metabolism during fasting in vivo.
Gubbiotti, Maria A., Hoek, Jan B., Iozzo, Renato V., Rodeck, Ulrich, Seifert, Erin L.   +4 more
core   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Structural Variation of Chondroitin Sulfate Chains Contributes to the Molecular Heterogeneity of Perineuronal Nets

Frontiers in Integrative Neuroscience, 2018
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain ...
Shinji Miyata, Satomi Nadanaka, Michihiro Igarashi, Hiroshi Kitagawa   +3 more
doaj   +1 more source

The time-dependent localization of Ki 67 antigen-positive cells in human skin wounds [PDF]

, 1993
A total of 77 human skin wounds with a post-infliction interval between 3 h and 7 months were investigated and the proliferation marker antigen Ki 67 was visualized in paraffin sections using a specific monoclonal antibody (MIB).
A. Nerlich, DC Brown, E Ralfkiaer, EA Hell, H Cottier, J Gerdes, J Gerdes, J-P Ortonne, J. T�bel, J. Wilske, JL Cordell, M Oehmichen, M Oehmichen, P Betz, P Betz, P Betz, P Block, P. Betz, R Ross, R. Penning, RMM McMinn, RV Vito De, W. Eisenmengen   +22 more
core   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Expression of transcription factors KLF2 and KLF4 is induced by the mammalian Golgi stress response

Cell Structure and Function
The Golgi stress response is a homeostatic mechanism that augments Golgi function when Golgi function becomes insufficient (Golgi stress). Glycosylation of the core proteins of proteoglycans is one of the important functions of the Golgi.
Kanae Sasaki, Reishi Tanaka, Iona Miyake, Miyu Sakamoto, Ryuya Tanaka, Azusa Tanaka, Misaki Terami, Ryota Komori, Mai Taniguchi, Sadao Wakabayashi, Hajime Tajima Sakurai, Hiderou Yoshida   +11 more
doaj   +1 more source