Individual Smad2 linker region phosphorylation sites determine the expression of proteoglycan and glycosaminoglycan synthesizing genes [PDF]
, 2019 Growth factors such as thrombin and transforming growth factor (TGF)-β facilitate glycosaminoglycan (GAG) chain hyperelongation on proteoglycans, a phenomenon that increases lipoprotein binding in the vessel wall and the development of atherosclerosis ...
Kamato, Danielle +7 more
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A Systematic Review of Extracellular Matrix-Related Alterations in Parkinson’s Disease
Brain SciencesThe role of the extracellular matrix (ECM) in Parkinson’s disease (PD) is not well understood, even though it is critical for neuronal structure and signaling.
Mary Ann Chapman, Barbara A. Sorg
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Divergent and co-localization of the two small proteoglycans decorin and proteoglycan-100 in human skeletal tissues and tumors. [PDF]
, 1993 The core protein of a recently described small proteoglycan, proteoglycan-100, was localized in fetal human tissues by indirect immunocytochemistry and compared with the localization of known members of the small proteoglycan family.
H Kresse, E Vollmer, K Schwarz, A Bosse
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Binding of von Willebrand factor to the small proteoglycan decorin [PDF]
, 2004 The small proteoglycan decorin plays an important role in the organisation of the extracellular matrix by binding to several components, including collagen and fibronectin.
Torti, Mauro +11 more
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Biomimetic strategies for the deputization of proteoglycan functions
Frontiers in Cell and Developmental BiologyProteoglycans (PGs), which have glycosaminoglycan chains attached to their protein cores, are essential for maintaining the morphology and function of healthy body tissues.
Ibrahim F. Rehan +5 more
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Proteoglycan-4: A Dynamic Regulator of Parathyroid Hormone Biologic Actions. [PDF]
, 2011 Intermittent parathyroid hormone (PTH) (1-34) is the only anabolic agent currently approved for the treatment of osteoporosis in the U.S. PTH (1-34) is under clinical investigations as a local bone regenerative therapy and as a potential stem cell ...
Novince, Chad M.
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Proteoglycan fragments in knee joint fluid after exercise [PDF]
, 1993 The concentration of cartilage proteoglycan fragments in knee joint fluid was measured before and after one event of physical exercise in 33 healthy athletes.
Dahlberg, L., Lohmander, L. S., Roos, H.
core
Journal of Investigative Dermatology, 1993 Proteoglycans are polymorphic macromolecules present in all mammalian tissues, including the skin and its appendages. They consist of a core protein to which one or more glycosaminoglycan chains are covalently attached. Broadly, they can be divided into classes based on location and core protein structure.
openaire +2 more sources
Distribution of proteoglycans antigenically related to corneal keratan sulfate proteoglycan [PDF]
, 1987 Three antibodies reacting with corneal keratan sulfate proteoglycan were used to detect antigenically related molecules in 11 bovine and 13 embryonic chick tissues. Two monoclonal antibodies recognized sulfated epitopes on the keratan sulfate chain and a
Caterson, B +2 more
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