Results 61 to 70 of about 82,646 (203)

Metabolism and turnover of cell surface-associated heparan sulfate proteoglycan and chondroitin sulfate proteoglycan in normal and cholesterol-enriched macrophages.

, 1991
Analysis of sulfur-35-labeled proteoglycans indicated that cholesterol-enriched pigeon peritoneal macrophages synthesized 42% more 35S-labeled proteoglycan when compared with control macrophages during a 24-hour incubation.
R T Owens, W D Wagner
core   +1 more source

Heparan sulfate and cell division

Brazilian Journal of Medical and Biological Research, 1999
Heparan sulfate is a component of vertebrate and invertebrate tissues which appears during the cytodifferentiation stage of embryonic development. Its structure varies according to the tissue and species of origin and is modified during neoplastic ...
Porcionatto M.A., Nader H.B., Dietrich C.P.   +2 more
doaj  

The Effects of Proteoglycan and Type II Collagen on T1ρ Relaxation Time of Articular Cartilage

대한영상의학회지, 2015
Purpose To evaluate the effects of proteoglycan and type II collagen within articular cartilage on T1ρ relaxation time of articular cartilage. Materials and Methods This study was exempted by the institutional and animal review boards, and informed ...
Won Seok Choi, Hye Jin Yoo, Sung Hwan Hong, Ja-Young Choi   +3 more
doaj   +1 more source

Neuroendocrine tumors show altered expression of chondroitin sulfate, glypican 1, glypican 5 and syndecan 2 depending on their differentiation grade

Frontiers in Oncology, 2014
Neuroendocrine tumors are found throughout the body and are important as they give rise to distinct clinical syndromes. Glycosaminoglycans, in proteoglycan form or as free chains, play vital roles in every step of tumor progression.
Olivia eGarcía-Suárez, Beatriz eGarcía, Iván eFernández-Vega, Aurora eAstudillo, Aurora eAstudillo, Luis M Quirós, Luis M Quirós   +6 more
doaj   +1 more source

Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy [PDF]

, 2015
Despite the availability of several therapies for rheumatoid arthritis (RA) that target the immune system, a large number of RA patients fail to achieve remission.
Esko, Jeffrey D, Bartok, Beatrix, Michel L. Tremblay, Ru Liu-Bryan, Nunzio Bottini, Cristiano Sacchetti, Stephanie M. Stanford, Arnett, Heather A, Karen M. Doody, Charlotte H. Coles, Cory, Esther, Firestein, Gary S, Mattias N. D. Svensson, David L. Boyle, A. Radu Aricescu, Mitakidis, Nikolaos, Mustelin, Tomas, Corr, Maripat, Stanford, Stephanie M, Tomas Mustelin, Sacchetti, Cristiano, Nikolaos Mitakidis, Doody, Karen M, Coles, Charlotte H, Beatrix Bartok, Bottini, Nunzio, Maripat Corr, Kiosses, William B, Sah, Robert L, Gary S. Firestein, William B. Kiosses, Robert L. Sah, Camille Fos, Heather A. Arnett, Liu-Bryan, Ru, Aricescu, A Radu, Jeffrey D. Esko, Tremblay, Michel L, Fos, Camille, Boyle, David L, Esther Cory, Svensson, Mattias ND   +41 more
core   +1 more source

Altered fibroblast proteoglycan production in COPD [PDF]

, 2010
Background Airway remodeling in COPD includes reorganization of the extracellular matrix. Proteoglycans play a crucial role in this process as regulators of the integrity of the extracellular matrix.
Dahlback, Magnus, Leif T Eriksson, Hallgren Oskar, Eriksson, Leif, Oskar Hallgren, Erjefält Jonas S, Bjermer Leif, Löfdahl, Claes-Göran, Westergren-Thorsson Gunilla, Claes-Göran Löfdahl, Gunilla Westergren-Thorsson, Nihlberg Kristian, Bjermer, Leif, Nihlberg, Kristian, Löfdahl Claes-Göran, Dahlbäck Magnus, Eriksson Leif T, Erjefält, Jonas, Leif Bjermer, Hallgren, Oskar, Jonas S Erjefält, Westergren-Thorsson, Gunilla, Kristian Nihlberg, Magnus Dahlbäck   +23 more
core   +1 more source

Proteoglycans as Therapeutic Targets in Brain Cancer

Frontiers in Oncology, 2020
Proteoglycans (PGs) are heavily glycosylated diverse proteins consisting of a “core protein” covalently attached to glycosaminoglycans (GAGs) and present on the cell surface, extracellular matrix, and intracellular milieu.
Zoya Yan, Shanzhi Wang
doaj   +1 more source

Soluble proteoglycans and proteoglycan fragments as biomarkers of pathological extracellular matrix remodeling

Proteoglycans and their proteolytic fragments diffuse into biological fluids such as plasma, serum, urine, or synovial fluid, where they can be detected by antibodies or mass-spectrometry.
Kemberi, Marsioleda, Minns, Alexander F, Santamaria, Salvatore   +2 more
core   +1 more source

Syndecan-4 Modulates Cell Polarity and Migration by Influencing Centrosome Positioning and Intracellular Calcium Distribution

Frontiers in Cell and Developmental Biology, 2020
Efficient cell migration requires cellular polarization, which is characterized by the formation of leading and trailing edges, appropriate positioning of the nucleus and reorientation of the Golgi apparatus and centrosomes toward the leading edge ...
Daniel Becsky, Kitti Szabo, Szuzina Gyulai-Nagy, Tamas Gajdos, Zsuzsa Bartos, Arpad Balind, Laszlo Dux, Peter Horvath, Miklos Erdelyi, Laszlo Homolya, Aniko Keller-Pinter   +10 more
doaj   +1 more source

Monoclonal antibodies to rabbit corneal keratan sulfate proteoglycan

, 1982
Six mouse hybrid cell lines were isolated which secrete antibodies to rabbit corneal proteoglycan. All six antibodies interacted with the same fraction of the proteoglycan, precipitating approximately 50% of proteoglycan labelled in the protein moiety. A
Funderburgh, James L., Chandler, John W., Stenzel-Johnson, Paule R.   +2 more
core   +1 more source