大腸菌を用いたフォスファカン（コンドロイチン硫酸プロテオグリカン）の融合コア蛋白の発現条件の検討 [PDF]
, 1996 Optimal conditions for expressing a specific region of core protein of phosphacan, a chondroitin sulfate proteoglycan known as receptor type protein tyrosine phosphatase, as fusion protein with glutathione S-transferase (GST) in E.coli were examined. DNA
Ito, Sekiko, Okamoto, Motoi
core +1 more source
Undervalued ubiquitous proteins
4 open, 2019 The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source
Biomolecules, 2020 Glycosaminoglycans (GAGs) are linear, structurally diverse, conformationally complex carbohydrate polymers that may contain up to 200 monosaccharides.
Elizabeth K. Whitmore +3 more
doaj +1 more source
Monoclonal antibodies to rabbit corneal keratan sulfate proteoglycan [PDF]
, 1982 Six mouse hybrid cell lines were isolated which secrete antibodies to rabbit corneal proteoglycan. All six antibodies interacted with the same fraction of the proteoglycan, precipitating approximately 50% of proteoglycan labelled in the protein moiety. A
Funderburgh, James L. +2 more
core +1 more source
An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix. [PDF]
, 1995 Agrin is an extracellular matrix (ECM) protein with a calculated relative molecular mass of more than 200 kD that induces the aggregation of acetylcholine receptors (AChRs) at the neuromuscular junction. This activity has been mapped to its COOH terminus.
Ruegg, M. A. +11 more
core +1 more source
Mutable Collagenous Tissue: A Concept Generator for Biomimetic Materials and Devices
Marine DrugsEchinoderms (starfish, sea-urchins and their close relations) possess a unique type of collagenous tissue that is innervated by the motor nervous system and whose mechanical properties, such as tensile strength and elastic stiffness, can be altered in a ...
M. Daniela Candia Carnevali +3 more
doaj +1 more source
Endocan - a potential diagnostic marker for early onset sepsis in neonates
Journal of Infection in Developing Countries, 2019 Introduction: Neonatal early onset sepsis assessment is based on the history of pregnancy and delivery and nonspecific clinical signs. None of the biomarkers currently in use for clinical practice has adequate prognostic value, so it is not possible to ...
Gabriela Ildiko Zonda +5 more
doaj +1 more source
Soluble proteoglycans and proteoglycan fragments as biomarkers of pathological extracellular matrix remodeling [PDF]
Proteoglycans and their proteolytic fragments diffuse into biological fluids such as plasma, serum, urine, or synovial fluid, where they can be detected by antibodies or mass-spectrometry.
Kemberi, Marsioleda +2 more
core +1 more source
The conserved transmembrane proteoglycan Perdido/Kon-tiki is essential for myofibrillogenesis and sarcomeric structure in Drosophila [PDF]
, 2014 M.B. was funded by a Wellcome Trust Senior Investigator Award to P. Lawrence (WT096645MA).Muscle differentiation requires the assembly of high-order structures called myofibrils, composed of sarcomeres.
Estrada, B +3 more
core +2 more sources
Glycosaminoglycans: Sweet as Sugar Targets for Topical Skin Anti-Aging
Clinical, Cosmetic and Investigational Dermatology, 2021 Siew Tein Wang, Boon Hoe Neo, Richard J Betts L’Oréal Research & Innovation, L’Oréal Singapore, SingaporeCorrespondence: Richard J Betts Email richard.betts@rd.loreal.comAbstract: Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of ...
Wang ST, Neo BH, Betts RJ
doaj