Results 31 to 40 of about 84,285 (265)

Undervalued ubiquitous proteins

4 open, 2019
The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Efficient Construction of Atomic-Resolution Models of Non-Sulfated Chondroitin Glycosaminoglycan Using Molecular Dynamics Data

Biomolecules, 2020
Glycosaminoglycans (GAGs) are linear, structurally diverse, conformationally complex carbohydrate polymers that may contain up to 200 monosaccharides.
Elizabeth K. Whitmore, Gabriel Vesenka, Hanna Sihler, Olgun Guvench   +3 more
doaj   +1 more source

HSPG2 (heparan sulfate proteoglycan 2) [PDF]

, 2009
Review on HSPG2 (heparan sulfate proteoglycan 2), with data on DNA, on the protein encoded, and where the gene is ...
Farach-Carson, MC, Grindel, B, B Grindel, MC Farach-Carson   +3 more
core   +1 more source

Mutable Collagenous Tissue: A Concept Generator for Biomimetic Materials and Devices

Marine Drugs
Echinoderms (starfish, sea-urchins and their close relations) possess a unique type of collagenous tissue that is innervated by the motor nervous system and whose mechanical properties, such as tensile strength and elastic stiffness, can be altered in a ...
M. Daniela Candia Carnevali, Michela Sugni, Francesco Bonasoro, Iain C. Wilkie   +3 more
doaj   +1 more source

Endocan - a potential diagnostic marker for early onset sepsis in neonates

Journal of Infection in Developing Countries, 2019
Introduction: Neonatal early onset sepsis assessment is based on the history of pregnancy and delivery and nonspecific clinical signs. None of the biomarkers currently in use for clinical practice has adequate prognostic value, so it is not possible to ...
Gabriela Ildiko Zonda, Radu Zonda, Andrei Tudor Cernomaz, Luminita Paduraru, Andreea Luciana Avasiloaiei, Bogdan Dragos Grigoriu   +5 more
doaj   +1 more source

Glycosaminoglycans: Sweet as Sugar Targets for Topical Skin Anti-Aging

Clinical, Cosmetic and Investigational Dermatology, 2021
Siew Tein Wang, Boon Hoe Neo, Richard J Betts L’Oréal Research & Innovation, L’Oréal Singapore, SingaporeCorrespondence: Richard J Betts Email richard.betts@rd.loreal.comAbstract: Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of ...
Wang ST, Neo BH, Betts RJ
doaj  

Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease

Biomedicines, 2023
Circulating biomarkers reflecting cardiac inflammation are needed to improve the diagnostics and guide the treatment of heart failure patients. The cardiac production and shedding of the transmembrane proteoglycan syndecan-4 is upregulated by innate ...
Mari E. Strand, Maarten Vanhaverbeke, Michiel T. H. M. Henkens, Maurits A. Sikking, Karoline B. Rypdal, Bjørn Braathen, Vibeke M. Almaas, Theis Tønnessen, Geir Christensen, Stephane Heymans, Ida G. Lunde   +10 more
doaj   +1 more source

The Role of Decorin and Biglycan Signaling in Tumorigenesis

Frontiers in Oncology, 2021
The complex and adaptive nature of malignant neoplasm constitute a major challenge for the development of effective anti-oncogenic therapies. Emerging evidence has uncovered the pivotal functions exerted by the small leucine-rich proteoglycans, decorin ...
Valentina Diehl, Lisa Sophie Huber, Jonel Trebicka, Malgorzata Wygrecka, Renato V. Iozzo, Liliana Schaefer   +5 more
doaj   +1 more source

Chondroitin sulfate proteoglycan and heparan sulfate proteoglycan production by cultured pigeon peritoneal macrophages

, 1992
Proteoglycan production was examined in cultures of thioglycollate-elicited peritoneal macrophages obtained from White Carneau and Show Racer pigeons.
William D Wagner, Rick T Owens
core   +1 more source

Interaction with proteoglycans enhances the sterol efflux produced by endogenous expression of macrophage apoE

Journal of Lipid Research, 2001
Endogenous expression of apolipoprotein (apo)E in macrophages facilitates cholesterol efflux in the presence and absence of extracellular sterol acceptors. A proteoglycan-associated pool of apoE has also been described.
Chen-Yi Lin, Zhi Hua Huang, Theodore Mazzone   +2 more
doaj   +1 more source